P3-178: Association between depressive symptoms, cognitive decline, and white matter integrity in cognitively normal adults with a family history of Alzheimer's disease

2012 ◽  
Vol 8 (4S_Part_14) ◽  
pp. P515-P516
Author(s):  
Grace Lee ◽  
Katie Smith ◽  
Lori Holleran ◽  
Ahra Ko ◽  
George Bartzokis ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Depressive Symptoms ◽  
White Matter ◽  
Family History ◽  
Cognitive Decline ◽  
White Matter Integrity ◽  
Cognitively Normal ◽  
History Of ◽  
Normal Adults

scholarly journals White matter integrity is associated with cerebrospinal fluid markers of Alzheimer's disease in normal adults

2014 ◽  
Vol 35 (10) ◽  
pp. 2263-2271 ◽  
Author(s):  
Brian T. Gold ◽  
Zude Zhu ◽  
Christopher A. Brown ◽  
Anders H. Andersen ◽  
Mary Jo LaDu ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cerebrospinal Fluid ◽  
White Matter ◽  
White Matter Integrity ◽  
Normal Adults

P1-438: NEUROPSYCHIATRIC BURDEN IS RELATED TO INCREASED AMYLOID BUT NOT TAU DEPOSITION IN LATE-MIDDLE- AGED COGNITIVELY NORMAL INDIVIDUALS WITH A FAMILY HISTORY OF ALZHEIMER'S DISEASE

2006 ◽  
Vol 14 (7S_Part_8) ◽  
pp. P478-P479
Author(s):  
Alexa Pichet Binette ◽  
Etienne Vachon-Presseau ◽  
Julie Gonneaud ◽  
Natalie L. Marchant ◽  
Pierre Bellec ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Family History ◽  
Middle Aged ◽  
Cognitively Normal ◽  
Normal Individuals ◽  
History Of

scholarly journals White matter is altered with parental family history of Alzheimer's disease

2010 ◽  
Vol 6 (5) ◽  
pp. 394-403 ◽  
Author(s):  
Barbara B. Bendlin ◽  
Michele L. Ries ◽  
Elisa Canu ◽  
Aparna Sodhi ◽  
Mariana Lazar ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
White Matter ◽  
Family History ◽  
History Of ◽  
Parental Family

Mnemonics Usage and Cognitive Decline in Age-Associated Memory Impairment

1997 ◽  
Vol 9 (1) ◽  
pp. 47-56 ◽  
Author(s):  
Gary W. Small ◽  
Asenath La Rue ◽  
Scott Komo ◽  
Andrea Kaplan
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Family History ◽  
Cognitive Decline ◽  
Memory Impairment ◽  
Memory Function ◽  
Subjective Memory ◽  
Memory Measure ◽  
History Of

To determine predictors of cognitive deterioration, the authors performed baseline and 1- to 5-year follow-up (mean ± SD = 2.5 ± 1.2 years) neuropsychological assessments on 36 persons (mean age ± SD = 62.1 ± 8.0; range = 50 to 81 years) with age-associated memory impairment. Subjects were recruited from a larger group of volunteers, had minimal medical comorbidity, and 25 of them had a family history of Alzheimer's disease. Baseline age and a subjective memory measure indicating reported frequency of mnemonics usage were significant decline predictors. Subjects reporting more frequent mnemonics use at baseline were more likely to show objective cognitive decline at follow-up. Baseline full-scale IQ, educational level, and family history of Alzheimer's disease failed to predict decline. These findings suggest that although age is the strongest decline predictor in some people with age-associated memory impairment, self-perception of memory function may also predict subsequent cognitive loss.

P3-100: HETEROGENEITY OF CEREBROSPINAL FLUID BIOMARKER LEVELS IN COGNITIVELY NORMAL INDIVIDUALS WITH A FAMILY HISTORY OF ALZHEIMER'S DISEASE

2014 ◽  
Vol 10 ◽  
pp. P664-P664
Author(s):  
N.M. Dowling ◽  
Sterling Johnson ◽  
Henrik Zetterberg ◽  
Barbara B. Bendlin ◽  
Carey Elizabeth Gleason ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cerebrospinal Fluid ◽  
Family History ◽  
Cognitively Normal ◽  
Normal Individuals ◽  
History Of ◽  
Fluid Biomarker

scholarly journals White matter microstructure in late middle-age: Effects of apolipoprotein E4 and parental family history of Alzheimer's disease

2014 ◽  
Vol 4 ◽  
pp. 730-742 ◽  
Author(s):  
Nagesh Adluru ◽  
Daniel J. Destiche ◽  
Sharon Yuan-Fu Lu ◽  
Samuel T. Doran ◽  
Alex C. Birdsill ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
White Matter ◽  
Family History ◽  
Middle Age ◽  
Age Effects ◽  
Apolipoprotein E4 ◽  
White Matter Microstructure ◽  
History Of ◽  
Parental Family
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