P4-238: O-GlcNAcylation increases the targeting of beta-amyloid precursor protein to plasma membrane

2012 ◽  
Vol 8 (4S_Part_19) ◽  
pp. P718-P718
Author(s):  
Yoon Sun Chung ◽  
Sungkwon Chung
Keyword(s):  
Plasma Membrane ◽  
Amyloid Precursor Protein ◽  
Beta Amyloid ◽  
Precursor Protein

scholarly journals The protease inhibitory properties of the Alzheimer's beta-amyloid precursor protein.

1990 ◽  
Vol 265 (16) ◽  
pp. 8983-8985 ◽  
Author(s):  
S Sinha ◽  
H F Dovey ◽  
P Seubert ◽  
P J Ward ◽  
R W Blacher ◽  
...  
Keyword(s):  
Amyloid Precursor Protein ◽  
Beta Amyloid ◽  
Precursor Protein

scholarly journals Secretion of beta-amyloid precursor protein involves multiple cleavage sites.

1994 ◽  
Vol 269 (1) ◽  
pp. 627-632
Author(s):  
Z. Zhong ◽  
J. Higaki ◽  
K. Murakami ◽  
Y. Wang ◽  
R. Catalano ◽  
...  
Keyword(s):  
Amyloid Precursor Protein ◽  
Beta Amyloid ◽  
Precursor Protein ◽  
Cleavage Sites

Understanding the structural requirements of cyclic sulfone hydroxyethylamines as hBACE1 inhibitors against Aβ plaques in Alzheimer's disease: a predictive QSAR approach

RSC Advances ◽  
2016 ◽  
Vol 6 (34) ◽  
pp. 28171-28186 ◽  
Author(s):  
Pravin Ambure ◽  
Kunal Roy
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Amyloid Precursor Protein ◽  
Beta Amyloid ◽  
Precursor Protein ◽  
Structural Requirements ◽  
Amyloid Aβ

Beta (β)-site amyloid precursor protein cleaving enzyme 1 (BACE1) is one of the most important targets in Alzheimer's disease (AD), which is responsible for production and accumulation of beta amyloid (Aβ).

Interleukin-1 stimulates the beta-amyloid precursor protein promoter

1990 ◽  
Vol 10 (4) ◽  
pp. 485-495 ◽  
Author(s):  
Robert J. Donnelly ◽  
Arnold J. Friedhoff ◽  
Bernard Beer ◽  
Arthur J. Blume ◽  
Michael P. Vitek
Keyword(s):  
Amyloid Precursor Protein ◽  
Interleukin 1 ◽  
Beta Amyloid ◽  
Precursor Protein
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