scholarly journals P3-560: THE ROLES OF ANXIETY AND FAMILY HISTORY OF DEMENTIA IN INFLUENCING SUBJECTIVE COGNITIVE DECLINE IN MIDDLE-AGED ADULTS FROM THE HEALTHY BRAIN PROJECT

2019 ◽  
Vol 15 ◽  
pp. P1189-P1190
Author(s):  
Lisa Bransby ◽  
Yen Ying Ying Lim ◽  
Nawaf Yassi ◽  
Rachel F. Buckley ◽  
2019 ◽  
Vol 15 ◽  
pp. P1539-P1539
Author(s):  
Eider M. Arenaza-Urquijo ◽  
Gemma Salvadó ◽  
Carolina Minguillón ◽  
Marta Crous-Bou ◽  
Gonzalo Sánchez-Benavides ◽  
...  

2015 ◽  
Vol 11 (7S_Part_2) ◽  
pp. P73-P73
Author(s):  
Mara ten Kate ◽  
Ernesto Sanz-Arigita ◽  
Betty M. Tijms ◽  
Alle Meije Wink ◽  
Montserrat Clerigue ◽  
...  

2013 ◽  
Vol 25 (6) ◽  
pp. 944-959 ◽  
Author(s):  
Megan L. Zuelsdorff ◽  
Corinne D. Engelman ◽  
Elliot M. Friedman ◽  
Rebecca L. Koscik ◽  
Erin M. Jonaitis ◽  
...  

2015 ◽  
Vol 11 (7S_Part_12) ◽  
pp. P573-P574
Author(s):  
Christopher R. Nicholas ◽  
N. Maritza Dowling ◽  
Lindsay R. Clark ◽  
Annie M. Racine ◽  
Rebecca L. Koscik ◽  
...  

2017 ◽  
Vol 23 (8) ◽  
pp. 617-626 ◽  
Author(s):  
Christopher R. Nicholas ◽  
N. Maritza Dowling ◽  
Annie M. Racine ◽  
Lindsay R. Clark ◽  
Sara E. Berman ◽  
...  

AbstractObjectives: The purpose of this study was to investigate the longitudinal trajectory of self- and informant-subjective cognitive complaints (SCC), and to determine if SCC predict longitudinal changes in objective measures (OM) of cognitive function. Methods: The study included healthy and cognitively normal late middle-aged adults enriched with a family history of AD who were evaluated at up to three visits over a 4-year period. At each visit (Visit 1–3), self- and informant-SCC and OM were evaluated. Linear mixed models were used to determine if the longitudinal rate of change of self- and informant-SCC were associated with demographic variables, depressive symptoms, family history (FH), and apolipoprotein epsilon 4 (APOE4) status. The same modeling approach was used to examine the effect of Visit 1 SCC on longitudinal cognitive change after controlling for the same variables. Results: At Visit 1, more self-SCC were associated with fewer years of education and more depressive symptoms. SCC were also associated with poorer performance on cognitive measures, such that more self-SCC at Visit 1 were associated with poorer performance on memory and executive functioning measures at Visit 1, while more informant-SCC were associated with faster rate of longitudinal decline on a measure of episodic learning and memory. FH and APOE4 status were not associated with SCC. Discussion: Self- and informant-SCC showed an association with OM, albeit over different time frames in our late middle-aged sample. Additional longitudinal follow-up will likely assist in further clarifying these relationships as our sample ages and more pronounced cognitive changes eventually emerge. (JINS, 2017, 23, 617–626)


2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S815-S816
Author(s):  
Christopher A Taylor ◽  
Erin D Bouldin ◽  
Lisa C McGuire

Abstract While adults aged 65 years and older are most at risk for chronic conditions, studies show that middle-aged adults aged 45–64 years also have growing numbers of comorbid chronic diseases. Regardless of age, managing chronic conditions requires decision-making abilities to manage treatments effectively. Symptoms of memory loss and confusion may impair a person’s ability to manage their health. This study examined chronic conditions in persons with subjective cognitive decline (SCD), defined as the self-reported experience of increased memory problems or confusion. Behavioral Risk Factor Surveillance System data from 2015–2017 were used to define SCD and disease status for eight chronic conditions (heart disease, stroke, cancer, arthritis, asthma, depression, diabetes, and chronic obstructive pulmonary disease) for adults 45–64 years from 49 states, District of Columbia, and Puerto Rico that collected data on cognitive decline. Among adults aged 45–64 years, 10.8% reported SCD. Among those with SCD, 77.4% had at least one chronic disease compared to 47.1% of those without SCD. Those with SCD had a higher prevalence for all eight conditions compared to those similarly-aged without SCD. Adults with at least one chronic condition were more likely to discuss their symptoms of SCD with a health care professional (54.2%) compared to those with no chronic conditions (30.3%). Poor management of chronic conditions can result in increased health care costs and might worsen existing symptoms of confusion and memory problems. Self-care interventions for chronic disease management should consider the importance of an individual’s cognitive status, including SCD.


Sign in / Sign up

Export Citation Format

Share Document