scholarly journals F2-05-03: SLEEP MEDICATION USE AND RISK OF DEMENTIA IN A BIRACIAL COHORT OF OLDER ADULTS

2019 ◽  
Vol 15 ◽  
pp. P523-P524
Author(s):  
Yue Leng ◽  
Katie L. Stone ◽  
Kristine Yaffe
2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 197-197
Author(s):  
Alexandra Wennberg ◽  
Loretta Anderson

Abstract Difficulty with sleep and falls are prevalent among older adults. Sleep medication use is associated with falls in older adults, but little is known about its impact in older adults with dementia. We used data from the 2011 National Health and Aging Trends Study to assess the association of low- versus high- frequency sleep medication use with falls in older adults with self-reported dementia. In our fully adjusted model, among those with dementia, high-frequency sleep medication users were more likely to fall than low-frequency sleep medication users (OR=3.86, 95% CI: 1.31, 11.37). Among those without dementia, high-frequency sleep medication users were more likely to fall than low-frequency sleep medication users (OR=1.40, 95% CI: 1.11, 1.77). Reducing sleep medication use in older adults with and without dementia may help reduce the risk of falls and fall-related outcomes in older adults.


2019 ◽  
Vol 34 (7) ◽  
pp. 449-455
Author(s):  
Jonathan H. Watanabe ◽  
Diane L. Chau

OBJECTIVE: To quantify relationship between anxiety and depression symptoms with every-night sleep medication use in the United States. DESIGN: A case-control analysis to measure association between subjects with anxiety and depression symptoms and sleep medication use. SETTING AND PATIENTS: Older adults (N = 7,590) from the National Health and Aging Trends Study. MAIN OUTCOME MEASURE: Sleep medication use every night. RESULTS: Presence of the four anxiety and depression symptoms was associated with nightly sleep medication use. Those who reported "felt down, depressed, or hopeless" almost every day had an odds ratio (OR) of 3.50 (95% confidence interval [CI] 2.28-5.37) compared with those who did not. Those who reported "little interest or pleasure in doing things" almost every day had an OR of 1.86 (95% CI 1.32-2.61) compared with those with symptoms less often. Those who reported "felt nervous, anxious, or on edge" more than half the days had an OR of 3.43 (95% CI 2.68-4.37) compared with those who experienced the symptom less frequently. Those who reported "unable to stop or control worrying" more than half the days had an OR of 2.91 (95% CI 2.25-3.77) compared with those who did not. CONCLUSION: Older adults with anxiety and depression are more likely to use sleep medications every night. Efforts must be undertaken to reduce anxiety and depression to mitigate excess consumption of sedatives.


2020 ◽  
Author(s):  
Rebecca Robbins ◽  
Ralph J. DiClemente ◽  
Andrea B. Troxel ◽  
Girardin Jean-Louis ◽  
Mark Butler ◽  
...  

2019 ◽  
Vol 15 ◽  
pp. P1195-P1196 ◽  
Author(s):  
Yue Leng ◽  
Katie L. Stone ◽  
Kristine Yaffe

2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Yaena Min ◽  
Pramit A. Nadpara ◽  
Patricia W. Slattum

Background. Very few studies have assessed the impact of poor sleep and sleep medication use on the risk of falls among community-dwelling older adults. The objective of this study was to evaluate the association between sleep problems, sleep medication use, and falls in community-dwelling older adults.Methods. The study population comprised a nationally representative sample of noninstitutionalized older adults participating in the 2010 Health and Retirement Study. Proportion of adults reporting sleep problems, sleep medication use, and fall was calculated. Multiple logistic regression models were constructed to examine the impact of sleep problems and sleep medication use on the risk of falls after controlling for covariates.Results. Among 9,843 community-dwelling older adults, 35.8% had reported a fall and 40.8% had reported sleep problems in the past two years. Sleep medication use was reported by 20.9% of the participants. Older adults who do have sleep problems and take sleep medications had a significant high risk of falls, compared to older adults who do not have sleep problems and do not take sleep medications. The other two groups also had significantly greater risk for falls.Conclusion. Sleep problems added to sleep medication use increase the risk of falls. Further prospective studies are needed to confirm these observed findings.


Drugs & Aging ◽  
2012 ◽  
Vol 29 (7) ◽  
pp. 565-576 ◽  
Author(s):  
Anna Zisberg ◽  
Efrat Shadmi ◽  
Gary Sinoff ◽  
Nurit Gur-Yaish ◽  
Einav Srulovici ◽  
...  

2019 ◽  
Vol 66 (3) ◽  
pp. 23-32
Author(s):  
Kathy Nguyen ◽  
Jonathan Watanabe

Background Falls are the leading cause of unintentional fatal and nonfatal injuries in seniors. Sleep medications are associated with adverse events risk in older adults. The objective of this study is to quantify the relationship between different levels of sleep medication use with falls and fall-related worries in United States adults aged 65 years and older using a nationally representative sample. Methods Using the 2011 National Health and Aging Trends Study, survey-weighted multiple logistic regression was used to determine the association between participants who reported sleep medication use and the outcomes: falls in the last month, falls in the last year, multiple falls in the last year, fall-related worries, and limitation of activities due to fall-related worries. Results In adjusted analyses, older adults who used sleep medications every night compared to non-users of sleep medications were at increased odds of falls in the last year with an odds ratio (OR) of 1.51 (95% confidence limit [CL] 1.27, 1.78) and of multiple falls with an OR = 1.67 (95% CL 1.35, 2.06). For those who used sleep medications less than every night compared to non-users, there were no statistically significant increased odds of fall outcomes. Older adults who used sleep medication most nights (5–6 nights per week) and every night compared to non-users had increased odds of having fall-related worries with an OR = 1.61 (95% CL 1.06, 2.45) and an OR = 1.32 (95% CL 1.11, 1.58), respectively. Conclusion Older adults who use sleep medication every night are at greater odds of experiencing falls and having fall-related worries. Increased involvement by pharmacists in the community setting and pharmacist-led comprehensive medication reviews are efforts that may reduce sleep medication use and result in fewer falls in older adults.


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