Preoperative Body Composition Measures as a Predictor of Postoperative Patient-Reported Outcomes

2017 ◽  
Vol 225 (4) ◽  
pp. S88
Author(s):  
Mohamed O. Mohamed ◽  
Naoki Takahashi ◽  
Christopher Welle ◽  
Michael Moynagh ◽  
Juliane Bingener
2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Kaoru Toguchi ◽  
Arata Nakajima ◽  
Yorikazu Akatsu ◽  
Masato Sonobe ◽  
Manabu Yamada ◽  
...  

Abstract Background Total knee arthroplasty (TKA) is the major surgical treatment for end-stage osteoarthritis (OA). Despite its effectiveness, there are about 20% of patients who are dissatisfied with the outcome. Predicting the surgical outcome preoperatively could be beneficial in order to guide clinical decisions. Methods One-hundred and ten knees of 110 consecutive patients who underwent TKAs for varus knees resulting from OA were included in this study. Preoperative varus deformities were evaluated by femorotibial angle (FTA), medial proximal tibial angle (MPTA) and lateral distal femoral angle (LDFA), and classified as a severe varus (SV) or a mild varus (MV) group. The osteophyte score (OS), which we developed originally, was also calculated based on the size of the osteophytes and classified as groups with more or less osteophytes. We compared preoperative and 1-year postoperative range of motion, the Knee Society Score, and Japanese Knee injury Osteoarthritis Outcome Score (KOOS) between SV and MV groups (varus defined by FTA, MPTA, or LDFA), in each group with more or less osteophytes. Results When varus deformities were defined by FTA, regardless of OS, postoperative KOOS subscales and/or the improvement rates were significantly higher in the SV group than in the MV group. When varus defined by MPTA, regardless of OS, there were no significant differences in postoperative KOOS subscales between groups. However, when varus defined by LDFA, scores for pain, activities of daily living (ADL), and quality of life (QOL) on postoperative KOOS and/or the improvement rates were significantly higher in the SV group than in the MV group only in patients with less osteophytes. No significant differences were found between groups in patients with more osteophytes. Conclusions We classified OA types by radiographic measurements of femur and tibia in combination with OS. Postoperative patient-reported outcomes were better in patients with SV knees but were poor in patients with knees with MV deformity and less osteophytes.


2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Joseph A. Weiner ◽  
Joseph E. Snavely ◽  
Daniel J. Johnson ◽  
Wellington K. Hsu ◽  
Alpesh A. Patel

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Shawyon Baygani, BS ◽  
Kristin Zieles,BS ◽  
Andrew Jea, MD, MHA

Background and Hypothesis: Chiari malformation type I (CM-I) is a common pediatric disorder in which the cerebellar tonsils herniate the foramen magnum with associated spinal symptoms. The purpose of this study is to determine if the preoperative Pediatric Quality of Life Inventory (PedsQL) score is predictive of intermediate-term PedsQL outcomes following Chiari decompression surgery. The utility of preoperative patient-reported outcomes (PROs) to postoperative PROs has been previously demonstrated in adult spine surgery. However, to our knowledge, there is currently no widely accepted tool to predict short-, intermediate-, or long-term outcomes after pediatric Chiari decompression surgery. Project Methods: A prospectively maintained database was retrospectively reviewed. Patients who underwent first-time decompression for symptomatic Chiari malformation were identified and grouped by their preoperative PedsQL scores: mild disability (score 80–100), moderate disability (score 60–80); and severe disability (score < 60). PedsQL outcomes were collected at 6-week, 3-month, and 6-month follow-up. Preoperative PedsQL subgroups were tested for an association with demographic, perioperative characteristics, and improvements between groups by one-way ANOVA, chi-square, or Wilcoxon signed rank test, where appropriate. Results: The postoperative patient- and parent-reported PedsQL values were significantly different between all three groups at 6-weeks, 3-months, and 6-months after surgery (p < 0.05), except at the 6-month timepoint for parent-reported outcomes (p = 0.111). Patients with higher preoperative disability demonstrated statistically significant greater improvements (compared to preoperative score) in parent-reported PedsQL at all timepoints after surgery, except at the 6-month parent-reported outcomes (p = 0.133). Conclusion: Patients with worse preoperative disability, as assessed by PedsQL, experienced lower absolute PedsQL scores at all timepoints after surgery but had greater improvement in short- and intermediate-term PROs. We conclude that PedsQL is an efficient and accurate tool that can quickly assess patient disability in the preoperative period and predict both short-term and long-term surgical outcomes.


2020 ◽  
Author(s):  
Jinhui Ma ◽  
Yan Yan ◽  
Weiguo Wang ◽  
Bailiang Wang ◽  
Debo Yue ◽  
...  

Abstract Bakground This meta-analysis was designed to compare postoperative patient-reported outcomes and reoperation rates following unicompartmental knee arthroplasty (UKA) between patients with full-thickness cartilage loss (FTCL) and partial-thickness cartilage loss (PTCL).Methods Multiple databases, including PubMed, Embase, Cochrane Library, and CNKI, were searched to identify studies comparing the Oxford Knee Score (OKS), American Knee Society (AKS) score, and reoperation rates between patients with FTCL and PTCL following UKA. Mean differences were calculated for continuous outcomes, and odds ratios were calculated for binary outcomes.Results A total of 613 UKAs (233 PTCL and 380 FTCL) from five retrospective cohort studies were included. Three studies compared OKSs after ≥2 years of follow-up. The mean difference in postoperative OKSs was significantly higher by 2.92 in the FTCL patients than in the PTCL patients (95% confidence interval [CI] −5.29 to −0.55; P = 0.02). The improvement in the OKS was significantly higher by 2.69 in the FTCL patients than in the PTCL patients (95 % CI −4.79 to −0.60; P = 0.01). AKS-knee and AKS-function scores were assessed in two studies at a mean follow-up time of >3.9 years. The mean difference in AKS-knee scores was similar between the groups (95%CI −9.14 to −3.34; P = 0.36), whereas the pooled mean difference in AKS-function scores was 5.63 higher in the FTCL group (95%CI −9.27 to −1.98; P = 0.002). All studies presented data on reoperation rates and showed that they were statistically higher in patients who underwent UKA with PTCL (OR 2.24, 95%CI 1.15–4.38, P = 0.02).Conclusions Compared with PTCL, FTCL achieved superior postoperative patient-reported outcomes and lower reoperation rates following UKA.


Cancer ◽  
2016 ◽  
Vol 122 (8) ◽  
pp. 1185-1200 ◽  
Author(s):  
Lauren C. Capozzi ◽  
Margaret L. McNeely ◽  
Harold Y. Lau ◽  
Raylene A. Reimer ◽  
Janine Giese-Davis ◽  
...  

2021 ◽  
Vol 21 (9) ◽  
pp. S163
Author(s):  
Braden McKnight ◽  
Zoë Fresquez ◽  
Paul O. Mgbam ◽  
Trevor Grieco ◽  
John A. Hipp ◽  
...  

Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2629
Author(s):  
Jie Lee ◽  
Tze-Chien Chen ◽  
Ya-Ting Jan ◽  
Chi-Jung Li ◽  
Yu-Jen Chen ◽  
...  

Pelvic radiotherapy is associated with gastrointestinal toxicities and deterioration of nutritional status. This study aimed to investigate the association of patient-reported outcomes (PROs) and nutritional status with body composition changes in women who underwent hysterectomy and post-operative radiotherapy for gynecologic cancer. We analyzed data of 210 patients treated with post-operative pelvic radiotherapy for gynecologic cancer between 2013 and 2018. The PRO version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) was used for gastrointestinal toxicity assessment. The Patient-Generated Subjective Global Assessment (PG-SGA) was used for nutritional assessment. Skeletal muscle index was measured from computed tomography scans at the L3 vertebral level. A reduction in skeletal muscle index ≥ 5% was classified as muscle loss. Odds ratios were calculated through logistic regression models. The PG-SGA score increased from the beginning to the end of radiotherapy (1.4 vs. 3.7, p < 0.001). Patients with PRO-CTCAE scores ≥ 3 had significantly higher PG-SGA scores at the end of radiotherapy than those with PRO-CTCAE scores ≤ 2 (8.1 vs. 2.3, p < 0.001). On multivariable analysis, PRO-CTCAE scores ≥ 3 and PG-SGA scores ≥ 4 at the end of radiotherapy were independently associated with increased risk of muscle loss (odds ratio: 8.81, p < 0.001; odds ratio: 72.96, p < 0.001, respectively). PROs and PG-SGA may be considered as markers of muscle loss after post-operative pelvic radiotherapy for gynecologic cancer.


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