Combined effect of elevated CO2 and temperature on growth, biomass and secondary metabolite of Hypericum perforatum L. in a western Himalayan region

Author(s):  
Shikha Sharma ◽  
Swati Walia ◽  
Shalika Rathore ◽  
Pawan Kumar ◽  
Rakesh Kumar
2012 ◽  
Vol 64 (1) ◽  
pp. 113-121 ◽  
Author(s):  
Sonja Gadzovska-Simic ◽  
O. Tusevski ◽  
S. Antevski ◽  
Natalija Atanasova-Pancevska ◽  
Jasmina Petreska ◽  
...  

We investigated the production of phenylpropanoids (phenolic compounds, flavanols, flavonols and anthocyanins) and naphtodianthrones (hypericins) in elicited Hypericum perforatum L. cell suspensions. To determine whether secondary metabolite production could be enhanced, Hypericum cell suspensions were exposed to mycelia extract from the fungus Aspergillus flavus. Elicited Hypericum cell suspension cultures displayed reduced growth and viability and a modification of secondary metabolites production. Anthocyanins were only stimulated in fungal-elicited cell suspensions. Secondary metabolite production in elicited Hypericum cells revealed an antagonism between the flavonoid/naphtodianthrone and anthocyanin pathways. The data suggest a modification of the channeling of the phenylpropanoid compounds. Together, these results represent useful data for monitoring the channeling in different secondary metabolite pathways during the scaled-up production of naphtodianthrones for medicinal uses.


PLoS ONE ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e87969 ◽  
Author(s):  
Paolo Domenici ◽  
Bridie J. M. Allan ◽  
Sue-Ann Watson ◽  
Mark I. McCormick ◽  
Philip L. Munday

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