Utility of subcategorization of atypia of undetermined significance/follicular lesion of undetermined significance category in ultrasound-guided thyroid fine-needle aspiration in a large referral cancer center

2019 ◽  
Vol 8 (6) ◽  
pp. 309-316
Author(s):  
Qiong Gan ◽  
Beth S. Edeiken ◽  
Melissa M. Chen ◽  
Elizabeth G. Grubbs ◽  
Naifa L. Busaidy ◽  
...  
2018 ◽  
Vol 126 (10) ◽  
pp. 846-852 ◽  
Author(s):  
Ricardo G. Pastorello ◽  
Camila Destefani ◽  
Pedro H. Pinto ◽  
Caroline H. Credidio ◽  
Rafael X. Reis ◽  
...  

2013 ◽  
Vol 85 (6) ◽  
pp. 380-385 ◽  
Author(s):  
Oktay Irkorucu ◽  
Enver Reyhan ◽  
Kamuran Cumhur Değer ◽  
Pelin Demirtürk ◽  
Hasan Erdem ◽  
...  

2019 ◽  
Vol 41 ◽  
pp. 112-115
Author(s):  
Aysegul Aksoy Altinboga ◽  
Canan Altunkaya ◽  
Hilal Ahsen ◽  
Berrak Gumuskaya ◽  
Oya Topaloglu ◽  
...  

2009 ◽  
Vol 117 (5) ◽  
pp. 298-304 ◽  
Author(s):  
Yan Shi ◽  
Xin Ding ◽  
Melissa Klein ◽  
Chiara Sugrue ◽  
Sandra Matano ◽  
...  

2021 ◽  
Vol 27 (1) ◽  
pp. 36-43
Author(s):  
Md Jaber Al Sayied ◽  
A Allam Choudhury ◽  
Sonia Jahan Bithi ◽  
Ashim Kumar Biswas ◽  
Riashat Azim Majumder ◽  
...  

Background: Fine-needle aspiration cytology (FNAC) is recommended as a decisive diagnostic step in the workup of patients with nodular thyroid disease. Unfortunately, FNAC can miss malignancies in smaller and deeper nodule. Ultrasound guided FNAC (US-FNAC) can reduce this error in suspicious thyroid nodule. Objectives: To find out the correlation of USG guided FNAC with postoperative histopathology in diagnosis of thyroid nodule. Methods: After obtaining clearance and approval from Institutional Review Board, all 45 patients of thyroid nodule who were admitted in the Department of Otolaryngology – Head & Neck surgery of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka from April 2017 to August 2018 and had fulfilled the inclusion and exclusion criteria were selected for the study. Each patient was assessed before surgery by USG guided FNAC and post operatively by histopathology. Results: In this study mean age of the respondents was 33.33 yearswith SD±10.84. Male female ration was 1:5.4. USG guided FNAC was reported by ‘The Bethesda System for Reporting Thyroid Cytopathology’ (TBS-RTC).Of the 45 specimens 2 samples were nondiagnostic or unsatisfactory (Class I), 26 samples were benign (Class II), 2 samples were showing Atypia of Undetermined Significance or Follicular lesion of Undetermined Significance (Class III), 6 were showing follicular neoplasm or suspicious for a follicular neoplasm (Class IV), 5 samples were suspicious for malignancy (Class V) and 4 samples were positive for malignancy (Class VI). On comparison of ultrasound guided FNAC with histopathology the sensitivity for correct diagnosis was 94%, specificity was 93%, positive predictive value was 88%, negative predictive value was 96% and accuracy was 93%. Pearson’s correlation coefficient was 0.85 which is very strong for positive relationship. Conclusion: USG guided FNAC is the most accurate method for diagnostic evaluation of thyroid nodules. Bangladesh J Otorhinolaryngol; April 2021; 27(1): 36-43


2019 ◽  
Vol 64 (4) ◽  
pp. 323-331 ◽  
Author(s):  
Sule Canberk ◽  
Kemal Behzatoglu ◽  
Can K. Caliskan ◽  
Serkan Gelmez ◽  
Kerem C. Kayhan ◽  
...  

Introduction: The Acibadem Health Group (AHG) has been using telepathology/digital pathology stations since 2006. In 2013, the system was changed from videoconferencing to digital pathology (whole-slide imaging) utilizing 3DHISTECH scanners and software. In 2017, digital cytology started to be used for routine cytopathologic diagnosis for thyroid fine-needle aspiration (FNA) cases. Material and Methods: Two hundred and twenty-seven thyroid cases were received for analysis using telecytology (TC) during the period from November 2017 to May 2018. Rapid on-site evaluation was performed at the Atakent Hospital of the AHG by a cytotechnologist and scanned on the same day. For every case, there were Diff-Quik- and Papanicolaou-stained FNA smears. Each glass slide was digitized with a 3DHISTECH whole-slide scanner in 1 focal Z-plane at ×40 magnification. Results: Two hundred and twenty-seven thyroid FNA specimens were retrieved, of which 25 had histologic follow-up. Samples were classified as nondiagnostic in 3%, benign in 74%, atypia of undetermined significance/follicular lesion of undetermined significance in 13%, suspicious for follicular neoplasia/follicular neoplasia in 3%, suspicious for malignancy in 4%, and malignant in 3%. When only the “suspicious for malignancy” and “malignancy” categories were considered positive tests, cytology sensitivity and specificity using TC for diagnosis was 100%. Conclusions: Our data demonstrate that TC is suitable to provide a primary diagnosis in daily routine cytology practice. Despite the promising results, there were some challenges stemming from the novelty of using TC for the primary diagnosis. The study also addresses both advantages and disadvantages of TC in daily practice to increase the efficiency of the technique in primary diagnosis.


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