A genetic explanation for the rising incidence of type 1 diabetes, a polygenic disease

2006 ◽  
Vol 27 (3) ◽  
pp. 174-181 ◽  
Author(s):  
Z AWDEH ◽  
E YUNIS ◽  
M AUDEH ◽  
D FICI ◽  
A PUGLIESE ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Genetic Explanation ◽  
Polygenic Disease ◽  
Rising Incidence

scholarly journals Type 1 Diabetes in the BB Rat: A Polygenic Disease

Diabetes ◽  
2009 ◽  
Vol 58 (4) ◽  
pp. 1007-1017 ◽  
Author(s):  
R. H. Wallis ◽  
K. Wang ◽  
L. Marandi ◽  
E. Hsieh ◽  
T. Ning ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Bb Rat ◽  
Polygenic Disease

scholarly journals Rising incidence of type 1 diabetes in Scottish children, 1984-93

1997 ◽  
Vol 77 (3) ◽  
pp. 210-213 ◽  
Author(s):  
J. J Rangasami ◽  
D. C Greenwood ◽  
B. McSporran ◽  
P. J Smail ◽  
C. C Patterson ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Rising Incidence

scholarly journals The Rising Incidence of Type 1 Diabetes Is Accounted for by Cases With Lower-Risk Human Leukocyte Antigen Genotypes

Diabetes Care ◽  
2008 ◽  
Vol 31 (8) ◽  
pp. 1546-1549 ◽  
Author(s):  
S. Fourlanos ◽  
M. D. Varney ◽  
B. D. Tait ◽  
G. Morahan ◽  
M. C. Honeyman ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Human Leukocyte Antigen ◽  
Lower Risk ◽  
Human Leukocyte ◽  
Leukocyte Antigen ◽  
Rising Incidence

Type 1 Diabetes—Pathogenesis, Prediction, and Prevention

2009 ◽  
Vol 05 (01) ◽  
pp. 79
Author(s):  
Peter R Baker II ◽  
George S Eisenbarth ◽  
◽  
Keyword(s):  
Type 1 Diabetes ◽  
Insulin Treatment ◽  
Early Recognition ◽  
Novel Technologies ◽  
Prediction And Prevention ◽  
The Us ◽  
Hereditary Component ◽  
Rising Incidence ◽  
Prevention Trials

Type 1 diabetes affects over 1.4 million people in the US, with a rising incidence in many western nations. It is clear that there is a strong hereditary component and that autoimmunity plays a large role in disease pathogenesis. In the last two decades novel technologies have been developed to study the genetics, biochemistry, and molecular pathology of type 1 diabetes. These, in turn, have allowed for early recognition of disease as well as the potential for prevention trials and early insulin treatment. This article highlights the prediction of type 1 diabetes risk and developing immunotherapeutic concepts.

Rapidly rising incidence of Type 1 diabetes in children and adolescents aged 0-19 years in Zhejiang, China, 2007 to 2013

2015 ◽  
Vol 33 (10) ◽  
pp. 1339-1346 ◽  
Author(s):  
H. B. Wu ◽  
J. M. Zhong ◽  
R. Y. Hu ◽  
H. Wang ◽  
W. W. Gong ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Children And Adolescents ◽  
Rising Incidence

Rising Incidence of Type 1 Diabetes in Hungarian Children (1978-1987)

1990 ◽  
Vol 7 (2) ◽  
pp. 111-114 ◽  
Author(s):  
G. Soltész ◽  
L. Madácsy ◽  
D. Békefi ◽  
I. Dankó ◽  
Keyword(s):  
Type 1 Diabetes ◽  
Rising Incidence

scholarly journals Rising Incidence of Type 1 Diabetes in Germany: 12-Year trend analysis in children 0-14 years of age

Diabetes Care ◽  
2001 ◽  
Vol 24 (4) ◽  
pp. 785-786 ◽  
Author(s):  
A. Neu ◽  
S. Ehehalt ◽  
A. Willasch ◽  
M. Kehrer ◽  
R. Hub ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Trend Analysis ◽  
Rising Incidence
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