Effect of a single impact loading on the structure and mechanical properties of articular cartilage

Impact loading of articular cartilage leads to post-traumatic osteoarthritis (OA) through its effects on the cells and extracellular matrix (ECM) of the tissue. Studies have shown the level of impact or injurious compression correlates with increased cell death, degradation of the ECM, and detrimental changes in biomechanical properties [1]. Recently, several bioactive agents, such as P188 and IGF-I, have shown promising results by reducing cell death following injurious compression of cartilage explants [2, 3].

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The influence of mechanical properties of subchondral plate, femoral head and neck on dynamic stress distribution of the articular cartilage

Medical Engineering & Physics ◽

10.1016/j.medengphy.2004.12.008 ◽

2005 ◽

Vol 27 (4) ◽

pp. 295-304 ◽

Cited By ~ 41

Author(s):

Hung-Wen Wei ◽

Shih-Sheng Sun ◽

Shyh-Hua Eric Jao ◽

Chiuan-Ren Yeh ◽

Cheng-Kung Cheng

Keyword(s):

Mechanical Properties ◽

Articular Cartilage ◽

Femoral Head ◽

Stress Distribution ◽

Head And Neck ◽

Dynamic Stress ◽

Subchondral Plate ◽

Dynamic Stress Distribution

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The generalized triphasic correspondence principle for simultaneous determination of the mechanical properties and proteoglycan content of articular cartilage by indentation

Journal of Biomechanics ◽

10.1016/j.jbiomech.2006.11.015 ◽

2007 ◽

Vol 40 (11) ◽

pp. 2434-2441 ◽

Cited By ~ 23

Author(s):

X. Lux Lu ◽

Chester Miller ◽

Faye H. Chen ◽

X. Edward Guo ◽

Van C. Mow

Keyword(s):

Mechanical Properties ◽

Articular Cartilage ◽

Simultaneous Determination ◽

Correspondence Principle ◽

Proteoglycan Content

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Sequential changes in the mechanical properties of viable articular cartilage storedin vitro

Journal of Orthopaedic Research® ◽

10.1002/jor.1100020109 ◽

1984 ◽

Vol 2 (1) ◽

pp. 55-60 ◽

Cited By ~ 13

Author(s):

Victor J. Thomas ◽

Sergio A. Jimenez ◽

Carl T. Brighton ◽

Norman Brown

Keyword(s):

Mechanical Properties ◽

Articular Cartilage

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Transversely isotropic micromechanics model to determine effect of collagen fibre angle in mechanical properties of articular cartilage

Materials Technology ◽

10.1179/1753555714y.0000000178 ◽

2014 ◽

Vol 29 (6) ◽

pp. 377-383 ◽

Cited By ~ 1

Author(s):

S. Mohammad Mehdi Elhamian ◽

M. Alizadeh ◽

M. Mehrdad Shokrieh ◽

A. Karimi ◽

S. Pejman Madani

Keyword(s):

Mechanical Properties ◽

Articular Cartilage ◽

Collagen Fibre ◽

Transversely Isotropic ◽

Micromechanics Model ◽

Fibre Angle ◽

Determine Effect

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Viscoelastic modeling of articular cartilage under impact loading

Meccanica ◽

10.1007/s11012-017-0717-y ◽

2017 ◽

Vol 53 (3) ◽

pp. 519-530 ◽

Cited By ~ 3

Author(s):

R. Springhetti ◽

N. S. Selyutina

Keyword(s):

Articular Cartilage ◽

Impact Loading ◽

Viscoelastic Modeling

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Permeability of Human Glenohumeral Joint Cartilage

10.1115/imece1999-0462 ◽

1999 ◽

Author(s):

Anna Stankiewicz ◽

Gerard A. Ateshian ◽

Louis U. Bigliani ◽

Van C. Mow

Keyword(s):

Mechanical Properties ◽

Articular Cartilage ◽

Interstitial Fluid ◽

Glenohumeral Joint ◽

Solid Matrix ◽

Joint Cartilage ◽

Frictional Drag ◽

Diarthrodial Joints ◽

Flow Through ◽

Fluid Pressurization

Abstract The nearly frictionless lubrication in diarthrodial joints and load support within articular cartilage depends on its mechanical properties. It has been shown that the majority of applied loads on cartilage are supported by interstitial fluid pressurization (Ateshian et al., 1994) which results from the frictional drag of flow through the porous permeable solid matrix. The duration and magnitude of this pressurization are a function of the permeability of cartilage (Lai et al., 1981).

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