scholarly journals Quantitative determination of the antitumor alkyl ether phospholipid edelfosine by reversed-phase liquid chromatography–electrospray mass spectrometry: application to cell uptake studies and characterization of drug delivery systems

2004 ◽  
Vol 810 (1) ◽  
pp. 85-92 ◽  
Author(s):  
María J. Blanco-Príeto ◽  
Miguel A. Campanero ◽  
Faustino Mollinedo
Keyword(s):  
Electrospray Mass Spectrometry ◽  
Reversed Phase ◽  
Cell Uptake ◽  
Alkyl Ether ◽  
Reversed Phase Liquid Chromatography ◽  
Phase Liquid ◽  
Uptake Studies ◽  
Mass Spectrometry Application

scholarly journals Determination of Alkylphenol Ethoxylates in Textiles by Normal-Phase Liquid Chromatography and Reversed-Phase Liquid Chromatography/Electrospray Mass Spectrometry

2007 ◽  
Vol 90 (5) ◽  
pp. 1411-1417 ◽  
Author(s):  
Chao Wang ◽  
Qiang Ma ◽  
Xing Wang
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Analytical Methods ◽  
Electrospray Mass Spectrometry ◽  
Reversed Phase ◽  
Normal Phase ◽  
Alkylphenol Ethoxylates ◽  
Reversed Phase Liquid Chromatography ◽  
Phase Liquid

Abstract Comprehensive analytical methods based on pressurized liquid extraction followed by normal-phase liquid chromatography (NPLC) with ultraviolet detection and reversed-phase liquid chromatography (RPLC)/electrospray mass spectrometry (MS) have been developed for determination of alkylphenol ethoxylates (APEOs) in textile samples. NPLC with an aminosilica column allowed for the chromatographic separation of APEOs according to the increasing number of ethylene units and revealed the exact distribution of individual oligomers. RPLC coupled with electrospray MS was highly sensitive and enabled the complete qualitative and quantitative determination of individual APEOs in textile samples. The 2 analytical methods based on different chromatographic separation mechanisms, i.e., NPLC and RPLC, may provide complementary information of APEOs in textile materials. The 2 detection methods were successfully applied to the investigation of various textile samples, and the data of our research suggested actual pollution in real textile products.

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