Brain tumors may alter the relationship between bispectral index values and propofol concentrations during induction of anesthesia

Abstract Background Studies on the relationship between psychiatric symptoms and brain tumors are ambiguous, as it is not clear whether these symptoms are due to the direct effect of the tumor or a secondary psychological response to stress, resulting from the diagnosis and treatment of the disease; therefore, it is difficult to analyze and retrieve relevant information. Case presentation We present the case of a 43-year-old male patient, who was admitted to a psychiatric emergency room with psychiatric symptoms, such as restlessness and extreme talkativeness, but normal neurological examinations. He showed no response to outpatient treatment and had no history of psychiatric disorders. The onset of symptoms was 2 months before his visit. On neuroimaging, a brain tumor was observed in the right temporal and occipital lobes. Accordingly, the patient was transferred to the neurosurgery ward. Conclusion Factors, such as increased internal pressure on the brain due to a brain tumor or the effect of tumor area, contribute to the occurrence of symptoms, such as restlessness and talkativeness. However, further studies are needed to confirm these findings.

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The cumulative duration of bispectral index less than 40 concurrent with hypotension is associated with 90-day postoperative mortality: a retrospective study

10.21203/rs.3.rs-16106/v1 ◽

2020 ◽

Author(s):

Soohyuk Yoon ◽

Seokha Yoo ◽

Min Hur ◽

Sun-Kyung Park ◽

Hyung-Chul Lee ◽

...

Keyword(s):

Risk Factors ◽

Retrospective Study ◽

Bispectral Index ◽

Odds Ratio ◽

Postoperative Mortality ◽

Anesthetic Depth ◽

Intraoperative Hypotension ◽

Cumulative Duration ◽

The Relationship ◽

Cumulative Time

Abstract Background The relationship between intraoperative low bispectral index (BIS) values and poor clinical outcomes has been controversial. Intraoperative hypotension is associated with postoperative complication. The purpose of this study was to investigate the influence of intraoperative low BIS values and hypotension on postoperative mortality in patients undergoing major abdominal surgery. Methods This retrospective study analyzed 1,862 cases of general anesthesia. We collected the cumulative time of BIS values below 20 and 40 as well as electroencephalographic suppression and documented the incidences in which these states were maintained for at least 5 minutes. Durations of intraoperative mean arterial pressures (MAP) less than 50 mmHg were also recorded. Multivariable logistic regression was used to evaluate the association between suspected risk factors and postoperative mortality. Results Ninety-day mortality and 180-day mortality were 1.5% and 3.2% respectively. The cumulative time in minutes for BIS values falling below 40 coupled with MAP falling below 50 mmHg was associated with 90-day mortality (odds ratio, 1.26; 95% confidence interval, 1.04-1.53; P = .019). We found no association between BIS related values and 180-day mortality. Conclusions Delicate adjustment of anesthetic depth is important to avoid excessive brain suppression and hypotension, which could be associated with postoperative mortality.

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The Relationship Between Bispectral Index and Electroencephalographic Parameters During Isoflurane Anesthesia

Anesthesia & Analgesia ◽

10.1213/01.ane.0000105867.17108.b6 ◽

2004 ◽

pp. 1336-1340 ◽

Cited By ~ 64

Author(s):

Yasuhiro Morimoto ◽

Satoshi Hagihira ◽

Yumika Koizumi ◽

Kazuyoshi Ishida ◽

Mishiya Matsumoto ◽

...

Keyword(s):

Bispectral Index ◽

Isoflurane Anesthesia ◽

The Relationship

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Oral processing speed as a key mechanism in the relationship between neurological risk and adaptive functioning in survivors of pediatric brain tumors

Pediatric Blood & Cancer ◽

10.1002/pbc.28575 ◽

2020 ◽

Vol 67 (11) ◽

Author(s):

Eric S. Semmel ◽

Tobiloba R. Quadri ◽

Tricia Z. King

Keyword(s):

Brain Tumors ◽

Processing Speed ◽

Adaptive Functioning ◽

Pediatric Brain Tumors ◽

Neurological Risk ◽

Oral Processing ◽

The Relationship ◽

Pediatric Brain

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Relationship between the national institutes health stroke scale score and bispectral index in patients with acute ischemic stroke

Journal of Experimental and Clinical Medicine ◽

10.52142/omujecm.38.4.7 ◽

2021 ◽

Vol 38 (4) ◽

pp. 440-444

Author(s):

Serdar ÖZDEMİR ◽

Tuba CİMİLLİ ÖZTÜRK ◽

Özge ECMEL ONUR

Keyword(s):

Ischemic Stroke ◽

Acute Ischemic Stroke ◽

Bispectral Index ◽

Sedative Drug ◽

Nihss Score ◽

Scale Scores ◽

History Of ◽

Clinically Significant ◽

Gcs Score ◽

The Relationship

This study aimed to investigate the relationship between the bispectral index and the National Institutes of Health Stroke Scale (NIHSS) score in patients admitted to the emergency department with a first-time acute ischemic stroke. Methods: This prospective, observational study was conducted with patients admitted to our clinic with acute ischemic stroke symptoms. Patients with known cranial pathologies, such as space- occupying lesions, those with a history of clinically significant cerebrovascular events or sedative drug administration, and those with altered consciousness due to metabolic causes were excluded from the study. The National Institutes Health Stroke Scale scores were recorded by the clinician. Cerebral arterial territories were assessed on DWI and CT. The relationship between the NIHSS score and bispectral index was evaluated. Results: Forty-three patients were included in the study. The mean bispectral index of the cases was 84.23 ± 9.50. There was no significant correlation between the bispectral index values and the NIHSS score (p<0.05). Conclusion: In our study, the bispectral index values were decreased due to ischemic stroke. The results should be reevaluated studies conducted with larger series to reveal the relationship between infarcted territories, NIHSS score, bispectral index, and the GCS score.

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