scholarly journals NCoR1 Protects Mice From Dextran Sodium Sulfate–Induced Colitis by Guarding Colonic Crypt Cells From Luminal Insult

2020 ◽  
Vol 10 (1) ◽  
pp. 133-147 ◽  
Author(s):  
Elvira Mennillo ◽  
Xiaojing Yang ◽  
Miles Paszek ◽  
Johan Auwerx ◽  
Christopher Benner ◽  
...  
Keyword(s):  
Sodium Sulfate ◽  
Dextran Sodium Sulfate ◽  
Colonic Crypt ◽  
Crypt Cells

Naringin protects against dextran sodium sulfate-induced colitis in mice

Planta Medica ◽  
2010 ◽  
Vol 76 (12) ◽  
Author(s):  
E Giner ◽  
M Marin ◽  
C Recio ◽  
J Ríos ◽  
R Giner
Keyword(s):  
Sodium Sulfate ◽  
Dextran Sodium Sulfate

Comparative effects of STW 5 and STW 5-II in dextran sodium sulfate-induced colitis

Planta Medica ◽  
2013 ◽  
Vol 79 (13) ◽  
Author(s):  
MT Khayyal ◽  
W Wadie ◽  
D Weiser ◽  
H Abdel-Aziz
Keyword(s):  
Sodium Sulfate ◽  
Dextran Sodium Sulfate

scholarly journals Ethanol Extract ofCordyceps militarisGrown on Germinated Soybeans Attenuates Dextran-Sodium-Sulfate- (DSS-) Induced Colitis by Suppressing the Expression of Matrix Metalloproteinases and Inflammatory Mediators

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Dong Ki Park ◽  
Hye-Jin Park
Keyword(s):  
Matrix Metalloproteinases ◽  
Inflammatory Mediators ◽  
Sodium Sulfate ◽  
Activity Index ◽  
Disease Activity Index ◽  
Ethanol Extract ◽  
Treated Group ◽  
Dextran Sodium Sulfate ◽  
Protective Agent ◽  
Colon Tissue

The effect ofCordyceps militaris(CM) grown on germinated soybeans (GSC) in the inflammatory bowel disease (IBD) model was studied. To demonstrate the preventive effect of GSC extract in a dextran-sodium-sulfate- (DSS-) induced acute colitis mouse model, GSC was administered 2 days before DSS coadministration. GSC significantly suppressed DSS-induced disease activity index (DAI) as well as histopathological scores, compared to control or CM-treated group. To elucidate the anti-IBD activity of GSC, we checked the level of matrix metalloproteinases (MMPs) and inflammatory mediators. GSC extract decreased the level of MMP-3 and -9 mRNAs and p53 proteins. The level and activity of LPS-induced MMP-9 were reduced in GSC-treated RAW264.7 cells. It also attenuated the level of inducible nitric oxide synthase (iNOS) and tumor necrosis factor- (TNF-)αmRNAs both in colon tissue and in macrophage cells. These results suggest that GSC can be applied as a protective agent against IBDs.

Beneficial Effect of Glatiramer Acetate Treatment on Syndecan-1 Expression in Dextran Sodium Sulfate Colitis

2011 ◽  
Vol 337 (2) ◽  
pp. 391-399 ◽  
Author(s):  
Doron Yablecovitch ◽  
Maytal Shabat-Simon ◽  
Rina Aharoni ◽  
Raya Eilam ◽  
Ori Brenner ◽  
...  
Keyword(s):  
Beneficial Effect ◽  
Glatiramer Acetate ◽  
Sodium Sulfate ◽  
Dextran Sodium Sulfate
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