scholarly journals Tofacitinib-induced modulation of intestinal adaptive and innate immunity and factors driving cellular and systemic pharmacokinetics

2021 ◽  
Author(s):  
Bernhard Texler ◽  
Andreas Zollner ◽  
Vera Reinstadler ◽  
Simon J. Reider ◽  
Sophie Macheiner ◽  
...  
Keyword(s):  
Innate Immunity ◽  
Adaptive And Innate Immunity

scholarly journals Mouse Mast Cell Tryptase mMCP-6 Is a Critical Link between Adaptive and Innate Immunity in the Chronic Phase ofTrichinella spiralisInfection

2008 ◽  
Vol 180 (7) ◽  
pp. 4885-4891 ◽  
Author(s):  
Kichul Shin ◽  
Gerald F. M. Watts ◽  
Hans C. Oettgen ◽  
Daniel S. Friend ◽  
Alan D. Pemberton ◽  
...  
Keyword(s):  
Innate Immunity ◽  
Mast Cell ◽  
Chronic Phase ◽  
Mast Cell Tryptase ◽  
Mouse Mast Cell ◽  
Adaptive And Innate Immunity ◽  
Critical Link

scholarly journals Immunosenescence as a reason of individualizing immunosuppressive therapy in kidney transplantation

2021 ◽  
Vol 23 (3) ◽  
pp. 171-179
Author(s):  
V. A. Fedulkina ◽  
A. V. Vatazin ◽  
A. V. Kildyushevskiy ◽  
A. B. Zulkarnayev ◽  
D. V. Gubina ◽  
...  
Keyword(s):  
Innate Immunity ◽  
Kidney Transplantation ◽  
Renal Transplant ◽  
Immunosuppressive Therapy ◽  
Immunosuppressive Drugs ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Optimal Balance ◽  
Underlying Diseases ◽  
Adaptive And Innate Immunity

Transplantation in elderly patients is obviously more challenging due to existing underlying diseases, changes in pharmacokinetics of immunosuppressive drugs, polypragmasy, and transformation of immunoreactivity (immunosenescence). Our review presents data on modification of adaptive and innate immunity during aging. It also considers the possibility of both reduced and adapted immunosuppressive therapy in elderly renal transplant recipients in achieving an optimal balance between efficacy and complications.

TL1A-DR3 Interactions are Important in Both Adaptive and Innate Immunity in Inflammatory Arthritis

2010 ◽  
Vol 135 ◽  
pp. S88 ◽  
Author(s):  
Yun-Jeong Song ◽  
Francoise Meylan ◽  
John Botson ◽  
Raphaela Goldbach-Mansky ◽  
David Lee ◽  
...  
Keyword(s):  
Innate Immunity ◽  
Inflammatory Arthritis ◽  
Adaptive And Innate Immunity

The Spleen

2017 ◽  
Author(s):  
Eric A Schinnerer ◽  
Jayleen M Grams
Keyword(s):  
Innate Immunity ◽  
Immune System ◽  
Key Words ◽  
Blood Cells ◽  
Normal Anatomy ◽  
Anatomy And Physiology ◽  
Lymphatic Organ ◽  
Adaptive And Innate Immunity

This review focuses on the normal anatomy and physiology of the spleen. The spleen functions as a hematologic organ, filtering blood, metabolizing iron, and acting as a reservoir for blood cells. The spleen, the largest lymphatic organ, also plays a key role in adaptive and innate immunity.    This review contains 7 figures of highly rendered artwork and 26 references. Key words: immune system, spleen, spleen anatomy, spleen physiology, splenectomy vaccine guidelines

The CARMA1 signalosome links the signalling machinery of adaptive and innate immunity in lymphocytes

2006 ◽  
Vol 6 (11) ◽  
pp. 799-812 ◽  
Author(s):  
David J. Rawlings ◽  
Karen Sommer ◽  
Miguel E. Moreno-García
Keyword(s):  
Innate Immunity ◽  
Adaptive And Innate Immunity

AB0021 Resistin Gene Transcription Is Regulated in Adaptive and Innate Immunity in Rheumatoid Arthritis

2016 ◽  
Vol 75 (Suppl 2) ◽  
pp. 904.1-904
Author(s):  
M. Andersen ◽  
M.K. Meyer ◽  
I. Nagaev ◽  
O. Nagaeva ◽  
J.E.S. WIkberg ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Innate Immunity ◽  
Gene Transcription ◽  
Adaptive And Innate Immunity

Changes in Adaptive and Innate Immunity in Patients with Acute Pancreatitis and Systemic Inflammatory Response Syndrome

Pancreatology ◽  
2011 ◽  
Vol 11 (5) ◽  
pp. 475-481 ◽  
Author(s):  
Vassiliki Mylona ◽  
Vassilios Koussoulas ◽  
Dimitrios Tzivras ◽  
Elias Makrygiannis ◽  
Panagiota Georgopoulou ◽  
...  
Keyword(s):  
Innate Immunity ◽  
Acute Pancreatitis ◽  
Systemic Inflammatory Response Syndrome ◽  
Inflammatory Response ◽  
Systemic Inflammatory Response ◽  
Adaptive And Innate Immunity
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