Clinicopathological parameters affecting nodal yields in patients with oral squamous cell carcinoma receiving selective neck dissection

2017 ◽  
Vol 45 (12) ◽  
pp. 2092-2096 ◽  
Author(s):  
Ali-Farid Safi ◽  
Martin Kauke ◽  
Andrea Grandoch ◽  
Hans-Joachim Nickenig ◽  
Uta Drebber ◽  
...  
Toukeibu Gan ◽  
2014 ◽  
Vol 40 (1) ◽  
pp. 16-22 ◽  
Author(s):  
Hiroyuki Harada ◽  
Ken Omura ◽  
Hiroaki Shimamoto

Cancers ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 269 ◽  
Author(s):  
Shunichi Shimura ◽  
Kazuhiro Ogi ◽  
Akihiro Miyazaki ◽  
Shota Shimizu ◽  
Takeshi Kaneko ◽  
...  

The most important prognostic factor in oral squamous cell carcinoma (OSCC) is neck metastasis, which is treated by neck dissection. Although selective neck dissection (SND) is a useful tool for clinically node-negative OSCC, its efficacy for neck node-positive OSCC has not been established. Sixty-eight OSCC patients with pN1–3 disease who were treated with curative surgery using SND and/or modified-radical/radical neck dissection (MRND/RND) were retrospectively reviewed. The neck control rate was 94% for pN1–3 patients who underwent SND. The five-year overall survival (OS) and disease-specific survival (DSS) in pN1-3 OSCC patients were 62% and 71%, respectively. The multivariate analysis of clinical and pathological variables identified the number of positive nodes as an independent predictor of SND outcome (OS, hazard ratio (HR) = 4.98, 95% confidence interval (CI): 1.48–16.72, p < 0.01; DSS, HR = 6.44, 95% CI: 1.76–23.50, p < 0.01). The results of this retrospective study showed that only SND for neck node-positive OSCC was appropriate for those with up to 2 lymph nodes that had a largest diameter ≤3 cm without extranodal extension (ENE) of the neck and adjuvant radiotherapy. However, the availability of postoperative therapeutic options for high-risk OSCC, including ENE and/or multiple positive lymph nodes, needs to be further investigated.


2007 ◽  
Vol 2 (1) ◽  
pp. 162
Author(s):  
A. Amar ◽  
S. Franzi ◽  
O. Curioni ◽  
M. Carvalho ◽  
A. Rapoport ◽  
...  

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