Quantitative evaluation of a hydrophilic matrix intravaginal ring for the sustained delivery of tenofovir

2012 ◽  
Vol 163 (2) ◽  
pp. 240-248 ◽  
Author(s):  
Justin T. Clark ◽  
Todd J. Johnson ◽  
Meredith R. Clark ◽  
Joel S. Nebeker ◽  
Judit Fabian ◽  
...  
Keyword(s):  
Quantitative Evaluation ◽  
Sustained Delivery ◽  
Hydrophilic Matrix ◽  
Intravaginal Ring

Engineering a degradable polyurethane intravaginal ring for sustained delivery of dapivirine

2011 ◽  
Vol 1 (3) ◽  
pp. 223-237 ◽  
Author(s):  
Manpreet Kaur ◽  
Kavita M. Gupta ◽  
Azadeh E. Poursaid ◽  
Prasoona Karra ◽  
Alamelu Mahalingam ◽  
...  
Keyword(s):  
Sustained Delivery ◽  
Intravaginal Ring

scholarly journals Controlling the hydration rate of a hydrophilic matrix in the core of an intravaginal ring determines antiretroviral release

2016 ◽  
Vol 224 ◽  
pp. 176-183 ◽  
Author(s):  
Ryan S. Teller ◽  
David C. Malaspina ◽  
Rachna Rastogi ◽  
Justin T. Clark ◽  
Igal Szleifer ◽  
...  
Keyword(s):  
Hydrophilic Matrix ◽  
Hydration Rate ◽  
The Core ◽  
Intravaginal Ring

scholarly journals An Intravaginal Ring for the Sustained Delivery of Antibodies

2014 ◽  
Vol 103 (11) ◽  
pp. 3611-3620 ◽  
Author(s):  
Manjula Gunawardana ◽  
Marc M. Baum ◽  
Thomas J. Smith ◽  
John A. Moss
Keyword(s):  
Sustained Delivery ◽  
Intravaginal Ring

scholarly journals Pharmacokinetics of a Multipurpose Pod-Intravaginal Ring Simultaneously Delivering Five Drugs in an Ovine Model

2013 ◽  
Vol 57 (8) ◽  
pp. 3994-3997 ◽  
Author(s):  
John A. Moss ◽  
Amanda M. Malone ◽  
Thomas J. Smith ◽  
Sean Kennedy ◽  
Cali Nguyen ◽  
...  
Keyword(s):  
Steady State ◽  
Sexually Transmitted Infections ◽  
Unintended Pregnancy ◽  
Sustained Delivery ◽  
Ovine Model ◽  
Sexually Transmitted ◽  
Intravaginal Rings ◽  
Wide Range ◽  
Intravaginal Ring ◽  
Proof Of Principle

ABSTRACTMultipurpose technologies that simultaneously protect from sexually transmitted infections and unintended pregnancy are urgently needed. Pod-intravaginal rings (IVRs) formulated with the antiretroviral agents (ARVs) tenofovir, nevirapine, and saquinavir and the contraceptives etonogestrel and estradiol were evaluated in sheep. Steady-state concentrations were maintained for 28 days with controlled, sustained delivery. This proof-of-principle study demonstrates that pod IVRs can deliver three ARVs from different mechanistic classes and a progestin-estrogen combination over the wide range needed for putative preventative efficacy.

scholarly journals An intravaginal ring for the sustained delivery of tenofovir disoproxil fumarate

2015 ◽  
Vol 495 (1) ◽  
pp. 579-587 ◽  
Author(s):  
Marc M. Baum ◽  
Irina Butkyavichene ◽  
Scott A. Churchman ◽  
Gilbert Lopez ◽  
Christine S. Miller ◽  
...  
Keyword(s):  
Tenofovir Disoproxil Fumarate ◽  
Sustained Delivery ◽  
Intravaginal Ring

A Hot-Melt Extruded Intravaginal Ring for the Sustained Delivery of the Antiretroviral Microbicide UC781

2012 ◽  
Vol 101 (2) ◽  
pp. 576-587 ◽  
Author(s):  
Meredith R. Clark ◽  
Todd J. Johnson ◽  
R. Tyler Mccabe ◽  
Justin T. Clark ◽  
Anthony Tuitupou ◽  
...  
Keyword(s):  
Sustained Delivery ◽  
Intravaginal Ring ◽  
Hot Melt

Quantitative evaluation of -ray spectra from scintillation measurements

Physica ◽  
1952 ◽  
Vol 18 (2) ◽  
pp. 1147-1150
Author(s):  
D MAEDER ◽  
V WINTERSTEIGER
Keyword(s):  
Quantitative Evaluation

Sustained delivery of salbutamol and beclometasone from spray-dried double emulsions

2009 ◽  
pp. 090624002829090
Author(s):  
Tristan P. Learoyd ◽  
Jane L. Burrows ◽  
Eddie French ◽  
Peter C. Seville
Keyword(s):  
Sustained Delivery ◽  
Double Emulsions ◽  
Spray Dried

Qualitative-Quantitative Evaluation of Depressive Symptomatology

2017 ◽  
Author(s):  
Francesca Serra ◽  
Andrea Spoto ◽  
Marta Ghisi ◽  
Giulio Vidotto
Keyword(s):  
Quantitative Evaluation ◽  
Depressive Symptomatology
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