Molecular epidemiology of rotavirus infections among children hospitalized for acute gastroenteritis in Shanghai, China, 2001 through 2005

Rotaviruses are the most common cause of severe viral gastroenteritis in early childhood worldwide. Thus, the objectives of our study were to determine the molecular epidemiology and the clinical features of rotavirus gastroenteritis in Tunisia. Between January 2003 and April 2007, a prospective study was conducted on 788 stool samples collected from children under 12 years of age who were suffering from acute gastroenteritis. Rotavirus was detected by multiplex RT-PCR in 27% (n = 213) of samples, among them 79.3% (n = 169) cases were monoinfections. The frequency of rotavirus infections was significantly higher among inpatients (29%) than among outpatients (13%) (P < 0.001). The seasonal distribution of rotavirus diarrhea showed a winter peak, with an unusual peak from June to September. The mean duration of hospitalization was 6.5 ± 8.1 days and the mean age was 15.8 ± 22.8 months for rotavirus monoinfections. Fever, vomiting, abdominal pain, and dehydration were observed in 88, 98, 13, and 80 cases, respectively, in children with rotavirus monoinfections. G3P[8] (45.6%) and G1P[8] (23.9%) were the most common genotypes found in our study. The determination of rotavirus infection prevalence and the characterization of the rotavirus strains circulating will help us to better understand the molecular biology and epidemiology of the disease in our country.

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Molecular epidemiology and genetic diversity of norovirus infection in children with acute gastroenteritis in Bangladesh, 2014‐2019

Journal of Medical Virology ◽

10.1002/jmv.26772 ◽

2021 ◽

Author(s):

Shuvra Kanti Dey ◽

Nadim Sharif ◽

Baki Billah ◽

Tanjir Tarek Ibn Siddique ◽

Tarequl Islam ◽

...

Keyword(s):

Genetic Diversity ◽

Molecular Epidemiology ◽

Acute Gastroenteritis

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Molecular epidemiology of norovirus from patients with acute gastroenteritis in northwestern Spain

Epidemiology and Infection ◽

10.1017/s0950268814000740 ◽

2014 ◽

Vol 143 (2) ◽

pp. 316-324 ◽

Cited By ~ 7

Author(s):

C. F. MANSO ◽

J. L. ROMALDE

Keyword(s):

Phylogenetic Analysis ◽

Molecular Epidemiology ◽

Genetic Drift ◽

Acute Gastroenteritis ◽

Age Groups ◽

Capsid Gene ◽

High Prevalence ◽

High Incidence ◽

Northwestern Spain

SUMMARYThe high incidence of norovirus (NoV) infections seems to be related to the emergence of new variants that evolved by genetic drift of the capsid gene. In this work, that represents a first effort to describe the molecular epidemiology of NoV in the northwest of Spain, a total of eight different NoV genotypes (GII.1, GII.3, GII.4, GII.6, GII.7, GII.12, GII.13, GII.14) were detected. The major genotypes observed were GII.4 (45·42%) and GII.14 (34·9%), being detected in all age groups. In addition, and although most of GII.4 sequences belonged to 2006b (7·2%) and 2010 (50·35%) variants, the presence of new NoV variants was observed. Phylogenetic analysis revealed that a high number of GII.4 sequences (35·24%) could be assigned to the newly emerging Sydney 2012 variant, even during late 2010. The high prevalence of NoV GII.14 observed in this study may indicate the emergence of this genotype in Spain.

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Molecular epidemiology of noroviruses in children under 5 years of age with acute gastroenteritis in Yaoundé, Cameroon

Journal of Medical Virology ◽

10.1002/jmv.25380 ◽

2019 ◽

Vol 91 (5) ◽

pp. 738-743 ◽

Cited By ~ 3

Author(s):

Akongnwi E. Mugyia ◽

Valentine N. Ndze ◽

Jane-Francis T. K. Akoachere ◽

Hannah Browne ◽

Angeline Boula ◽

...

Keyword(s):

Molecular Epidemiology ◽

Acute Gastroenteritis ◽

Children Under 5

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Molecular epidemiology of human bocavirus infection in hospitalized children with acute gastroenteritis in South Africa, 2009‐2015

Journal of Medical Virology ◽

10.1002/jmv.25634 ◽

2019 ◽

Vol 92 (8) ◽

pp. 1124-1132 ◽

Cited By ~ 5

Author(s):

Rembuluwani Netshikweta ◽

Lizyben Chidamba ◽

Sandrama Nadan ◽

Maureen B. Taylor ◽

Nicola A. Page

Keyword(s):

South Africa ◽

Molecular Epidemiology ◽

Acute Gastroenteritis ◽

Human Bocavirus ◽

Hospitalized Children

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Molecular epidemiology of human rotaviruses: Analysis of outbreaks of acute gastroenteritis in Glasgow and the west of Scotland 1981/82 and 1982/83

Journal of Hygiene ◽

10.1017/s0022172400064238 ◽

1984 ◽

Vol 92 (2) ◽

pp. 209-222 ◽

Cited By ~ 28

Author(s):

E. A. C. Follett ◽

R. C. Sanders ◽

G. M. Beards ◽

Fiona Hundley ◽

U. Desselberger

Keyword(s):

Molecular Epidemiology ◽

Pattern Analysis ◽

First Year ◽

The West ◽

Subgroup Ii ◽

Elisa Testing ◽

Serotype 1 ◽

Winter Peak ◽

First Year Of Life ◽

Rotavirus Infections

SUMMARYThe molecular epidemiology of rotavirus infections in Glasgow and the west of Scotland during 1981/82 and 1982/83 was investigated by electron microscopy, ELISA testing and RNA migration pattern analysis. In 1981/82, rotaviruses of both the ‘long’ and the ‘short’ electropherotype (in different variants) co-circulated from the onset throughout the winter peak of the outbreak. Approximately 80 % of the children were infected during the first year of life. No differences in incidence were found between sexes. In 1982/83 the isolated rotaviruses were almost exclusively of the ‘long’ electropherotype (in different variants) and 36% of the children were infected beyond the first year of life. Rotaviruses of the ‘long’ electropherotype serologically were of subgroup II and serotype 1 and those of the ‘short’ electropherotype of subgroup I and serotype 2.

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