scholarly journals A qualitative PCR minipool strategy to screen for virologic failure and antiretroviral drug resistance in South African patients on first-line antiretroviral therapy

2014 ◽  
Vol 60 (4) ◽  
pp. 387-391 ◽  
Author(s):  
Howard Newman ◽  
Lukas Breunig ◽  
Gert van Zyl ◽  
August Stich ◽  
Wolfgang Preiser
Keyword(s):  
Drug Resistance ◽  
Antiretroviral Therapy ◽  
South African ◽  
Virologic Failure ◽  
First Line ◽  
Antiretroviral Drug Resistance ◽  
Antiretroviral Drug ◽  
African Patients ◽  
Qualitative Pcr

scholarly journals Eight-day Inpatient Directly Observed Therapy for Antiretroviral Therapy (ART) Failure: A Tool For Preventing Unnecessary ART Changes and Optimizing Adherence Support

2019 ◽  
Vol 70 (6) ◽  
pp. 1222-1225 ◽  
Author(s):  
Nicole E Winchester ◽  
Frank Maldarelli ◽  
Yolanda Mejia ◽  
Nicola Dee ◽  
Robin Dewar ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Drug Resistance ◽  
Antiretroviral Therapy ◽  
Virologic Failure ◽  
Directly Observed Therapy ◽  
Antiretroviral Drug Resistance ◽  
Antiretroviral Drug ◽  
Adherence Support ◽  
Immunodeficiency Virus

Abstract Eight-day inpatient directly observed therapy confirmed nonadherence as the major cause of virologic failure for 9 (45%) of 20 highly treatment-experienced persons with human immunodeficiency virus, extensive antiretroviral drug resistance, and high self-reported adherence rates, preventing unnecessary regimen changes.

“I’m not that good with taking pills every day”

HIV ◽  
2020 ◽  
pp. 29-36
Author(s):  
Blake Max
Keyword(s):  
Drug Resistance ◽  
Antiretroviral Therapy ◽  
Virologic Failure ◽  
Undetectable Viral Load ◽  
New Drugs ◽  
Hiv Resistance ◽  
Antiretroviral Drug ◽  
Extensive Drug Resistance ◽  
Drug Regimens ◽  
Resistance Tests

The treatment goal of antiretroviral therapy is to achieve and maintain an undetectable viral load. Patients on antiretroviral therapy who do not achieve this goal can develop drug resistance to one or more drugs in the regimen. Poor medication adherence is the most likely reason for virologic failure and the development of drug resistance. Development of new drugs and clinical availability of HIV resistance tests has given providers more options for treatment-experienced patients with extensive drug resistance. Evaluating patients with extensive drug resistance requires knowledge of previous antiretroviral drug regimens, previous drug resistance tests, and interpretation of those tests. Managing treatment-experienced patients can be complex and may require consultation with an HIV expert.

scholarly journals Virological Response and Antiretroviral Drug Resistance Emerging during Antiretroviral Therapy at Three Treatment Centers in Uganda

PLoS ONE ◽  
2015 ◽  
Vol 10 (12) ◽  
pp. e0145536 ◽  
Author(s):  
Pontiano Kaleebu ◽  
Wilford Kirungi ◽  
Christine Watera ◽  
Juliet Asio ◽  
Fred Lyagoba ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Antiretroviral Therapy ◽  
Virological Response ◽  
Antiretroviral Drug Resistance ◽  
Antiretroviral Drug

scholarly journals Antiretroviral Drug Resistance in HIV-1–Infected Patients Experiencing Persistent Low-Level Viremia During First-Line Therapy

2011 ◽  
Vol 204 (4) ◽  
pp. 515-520 ◽  
Author(s):  
Babafemi Taiwo ◽  
Sebastien Gallien ◽  
Evgenia Aga ◽  
Heather Ribaudo ◽  
Richard Haubrich ◽  
...  
Keyword(s):  
Drug Resistance ◽  
First Line ◽  
Low Level ◽  
Antiretroviral Drug Resistance ◽  
First Line Therapy ◽  
Line Therapy ◽  
Antiretroviral Drug ◽  
Hiv 1

Prevalence of Antiretroviral Drug Resistance Mutations Among Pretreatment and Antiretroviral Therapy-Failure HIV Patients in Uzbekistan

2021 ◽  
Vol 37 (1) ◽  
pp. 38-43
Author(s):  
Adkhamjon Mamatkulov ◽  
Evgeniya Kazakova ◽  
Nargiz Ibadullaeva ◽  
Elizaveta Joldasova ◽  
Allabergan Bayjanov ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Antiretroviral Therapy ◽  
Resistance Mutations ◽  
Therapy Failure ◽  
Hiv Patients ◽  
Antiretroviral Drug Resistance ◽  
Drug Resistance Mutations ◽  
Antiretroviral Drug

scholarly journals HIV Type 1 Subtype C Drug Resistance among Pediatric and Adult South African Patients Failing Antiretroviral Therapy

2008 ◽  
Vol 24 (11) ◽  
pp. 1449-1454 ◽  
Author(s):  
Visva Pillay ◽  
Candice Pillay ◽  
Rami Kantor ◽  
Francois Venter ◽  
Leon Levin ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Antiretroviral Therapy ◽  
South African ◽  
Subtype C ◽  
Hiv Type 1 ◽  
African Patients
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