scholarly journals Serum prolactin levels in dermatological diseases: A case–control study

2015 ◽  
Vol 19 (2) ◽  
pp. 104-107 ◽  
Author(s):  
Nadia Abdalhafid Elsherif ◽  
Abdalla I. El-Sherif ◽  
Salwa A. El-Dibany
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Serum Prolactin ◽  
Dermatological Diseases ◽  
Control Study

SERUM PROLACTINE LEVEL IN PATIENTS OF PSORIASIS VULGARIS AND ITS CORRELATION WITH DISEASE SEVERITY: A CASE-CONTROL STUDY

2019 ◽  
Vol 3 (6) ◽  
Author(s):  
Pawan Kumar Saini ◽  
Devendra Yadav ◽  
Rozy Badyal ◽  
Suresh Jain ◽  
Arti Singh ◽  
...  
Keyword(s):  
Disease Severity ◽  
Prolactin Level ◽  
Case Control Study ◽  
Statistical Significance ◽  
Case Control ◽  
Serum Prolactin ◽  
P Value ◽  
Serum Prolactin Level ◽  
R Value ◽  
Control Study

Background: Psoriasis is an autoimmune chronic inflammatory disorder affecting the skin mediated by T-lymphocytes resulting in production of cytokines which cause hyperproliferation of keratinocytes.  Several factors and hormones like Prolactin have an action similar to these cytokines in promoting the multiplication of keratinocytes and other cells like lymphocytes and epithelial cells may have a role on the etiopathogenesis of psoriasis. Aim:-The aim of study is to compare the serum Prolactin levels in patients of psoriasis with a control group. Setting and study design: This is a case-control study conducted in the department of Dermatology, Venereology and Leprosy GMC, Kota over a period of 1year from July 2017 to June 2018 Material and method: The study included 100 cases of psoriasis (60 males and 40 females) and 100 controls similar for age and sex. Serum Prolactin levels were measured by ECLIA and results were obtained. Statistical analysis: Mean and standard deviation were calculated for each variable. Statistical significance of the results was analyzed using correlation analysis (Pearson correlation coefficient) and independent samples t-test. Statistical significance was assumed at p value<0.05. Result: Serum Prolactin level was significantly higher in cases of psoriasis compared to controls (p-value <0.001). PASI score and serum Prolactin levels were found to have a positive correlation (r value = 0.337; p-value: 0.001). No significant  correlation was found between serum levels of Prolactin and duration of disease r value= -0.034, P value =0.733). Serum Prolactin level was higher in male patients compared to females patients. Conclusion:- High serum Prolactin may be a biological marker of disease severity in psoriasis and may have a role in the pathogenesis of psoriasis. Further studies with large sample size are required to confirm this hypothesis.

scholarly journals TO DETERMINE THE SERUM PROLACTIN LEVELS IN BREAST CARCINOMA: A CASE CONTROL STUDY

2020 ◽  
Vol 4 (10) ◽  
Author(s):  
Sahun . ◽  
Sumita A. Jain ◽  
Ashutosh . ◽  
Dikhsa Mehta
Keyword(s):  
Breast Cancer ◽  
Prolactin Level ◽  
Case Control Study ◽  
Serum Insulin ◽  
Insulin Level ◽  
Case Control ◽  
Serum Prolactin ◽  
Serum Insulin Level ◽  
Serum Prolactin Level ◽  
Control Study

Background: Breast cancer is the most common female cancer worldwide representing nearly a quarter (25%) of all cancers with an estimated 1.67 million new cancer cases diagnosed in 2012. Methods: The study was conducted in the Department of General Surgery, SMS Hospital, Jaipur. Study duration: From March 2018 to February 2019 (1 year). Results: In Cancer cases, Mean Serum Prolactin level was found to be 14.71±16.73 while in control it was 8.26±5.60 .Mean Serum insulin level was higher in Cancer cases (14.71) as compared to control (8.26).Range of prolactin level in breast cancer cases from 2.84 to 103.71 and Range of prolactin level in controls was from 2.79 to 33.12 Difference was found to significant. Conclusion: By this study we can interpretate that serum prolactin level is an independent factor and can be used to know the risk of breast cancer in postmenopausl women. whenever serum prolactin level is raised in these women, we can advise necessary measure to these women to prevent or identify early breast cancer. Keywords: Breast, cancer, Female

scholarly journals Evaluation of the Diagnostic Significance of Some Biomarkers in Pruritic Dermatological Diseases: A Case-Control Study

2021 ◽  
Vol 31 (2) ◽  
pp. 86-92
Author(s):  
Neşe Başak TÜRKMEN ◽  
Dursun TÜRKMEN ◽  
Hande YÜCE ◽  
Mücahit MARSAK ◽  
Zübeyde TANRIVERDİ ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Diagnostic Significance ◽  
Dermatological Diseases ◽  
Control Study

scholarly journals Evaluation of Serum Gonadotropin and Prolactin Level among Sudanese Patients with Chronic Renal Failure

2021 ◽  
Author(s):  
Maha Fathalla ◽  
AbdElkarim A. Abdrabo ◽  
GadAllah Modawe
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Case Control Study ◽  
Case Control ◽  
Serum Prolactin ◽  
P Value ◽  
Serum Hormones ◽  
Serum Gonadotropin ◽  
Plasma Hormones ◽  
Control Study

Background: Generally, patients on hemodialysis for chronic renal failure also have endocrine defects and sexual function disorders. In this study, we aimed to assess the serum prolactin (PRL), luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in patients with chronic renal failure. Methods: This hospital-based case–control study was conducted at Jabal Aulia Teaching Hospital, Khartoum, Sudan. The study was carried out between August 2019 and February 2020. A total of 100 subjects were enrolled – 50 chronic renal failure patients and 50 as controls. The serum hormones were estimated using Tosoh 360. SPSS version 25 was used to analyze the results. Results: The serum PRL, LH, and FSH were significantly increased among chronic renal failure patients than their healthy counterparts (p-value = 0.000). The age of patients was positive correlated with plasma hormones, PRL (r = 0.332, p = 0.001), LH (r = 0.387, p = 0.000), and FSH (r = 0.320, p = 0.001). No correlation was found between the duration of the disease and serum hormones. Conclusion: Patients with chronic renal failure had a highly significant increase of serum PRL, LH, and FSH and also the age of the patients was positively correlated with serum hormones. Keywords: chronic renal failure, prolactin, gonadotropin, hemodialysis

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