scholarly journals TO DETERMINE THE SERUM PROLACTIN LEVELS IN BREAST CARCINOMA: A CASE CONTROL STUDY

2020 ◽  
Vol 4 (10) ◽  
Author(s):  
Sahun . ◽  
Sumita A. Jain ◽  
Ashutosh . ◽  
Dikhsa Mehta
Keyword(s):  
Breast Cancer ◽  
Prolactin Level ◽  
Case Control Study ◽  
Serum Insulin ◽  
Insulin Level ◽  
Case Control ◽  
Serum Prolactin ◽  
Serum Insulin Level ◽  
Serum Prolactin Level ◽  
Control Study

Background: Breast cancer is the most common female cancer worldwide representing nearly a quarter (25%) of all cancers with an estimated 1.67 million new cancer cases diagnosed in 2012. Methods: The study was conducted in the Department of General Surgery, SMS Hospital, Jaipur. Study duration: From March 2018 to February 2019 (1 year). Results: In Cancer cases, Mean Serum Prolactin level was found to be 14.71±16.73 while in control it was 8.26±5.60 .Mean Serum insulin level was higher in Cancer cases (14.71) as compared to control (8.26).Range of prolactin level in breast cancer cases from 2.84 to 103.71 and Range of prolactin level in controls was from 2.79 to 33.12 Difference was found to significant. Conclusion: By this study we can interpretate that serum prolactin level is an independent factor and can be used to know the risk of breast cancer in postmenopausl women. whenever serum prolactin level is raised in these women, we can advise necessary measure to these women to prevent or identify early breast cancer. Keywords: Breast, cancer, Female

SERUM PROLACTINE LEVEL IN PATIENTS OF PSORIASIS VULGARIS AND ITS CORRELATION WITH DISEASE SEVERITY: A CASE-CONTROL STUDY

2019 ◽  
Vol 3 (6) ◽  
Author(s):  
Pawan Kumar Saini ◽  
Devendra Yadav ◽  
Rozy Badyal ◽  
Suresh Jain ◽  
Arti Singh ◽  
...  
Keyword(s):  
Disease Severity ◽  
Prolactin Level ◽  
Case Control Study ◽  
Statistical Significance ◽  
Case Control ◽  
Serum Prolactin ◽  
P Value ◽  
Serum Prolactin Level ◽  
R Value ◽  
Control Study

Background: Psoriasis is an autoimmune chronic inflammatory disorder affecting the skin mediated by T-lymphocytes resulting in production of cytokines which cause hyperproliferation of keratinocytes.  Several factors and hormones like Prolactin have an action similar to these cytokines in promoting the multiplication of keratinocytes and other cells like lymphocytes and epithelial cells may have a role on the etiopathogenesis of psoriasis. Aim:-The aim of study is to compare the serum Prolactin levels in patients of psoriasis with a control group. Setting and study design: This is a case-control study conducted in the department of Dermatology, Venereology and Leprosy GMC, Kota over a period of 1year from July 2017 to June 2018 Material and method: The study included 100 cases of psoriasis (60 males and 40 females) and 100 controls similar for age and sex. Serum Prolactin levels were measured by ECLIA and results were obtained. Statistical analysis: Mean and standard deviation were calculated for each variable. Statistical significance of the results was analyzed using correlation analysis (Pearson correlation coefficient) and independent samples t-test. Statistical significance was assumed at p value<0.05. Result: Serum Prolactin level was significantly higher in cases of psoriasis compared to controls (p-value <0.001). PASI score and serum Prolactin levels were found to have a positive correlation (r value = 0.337; p-value: 0.001). No significant  correlation was found between serum levels of Prolactin and duration of disease r value= -0.034, P value =0.733). Serum Prolactin level was higher in male patients compared to females patients. Conclusion:- High serum Prolactin may be a biological marker of disease severity in psoriasis and may have a role in the pathogenesis of psoriasis. Further studies with large sample size are required to confirm this hypothesis.

Reproductive Factors and Risk of Breast Cancer by Tumour Subtypes Among Ghanaian Women: A Population-Based Case-Control Study

2019 ◽  
Author(s):  
Jonine Figueroa ◽  
Brittny C. Davis Lynn ◽  
Lawrence Edusei ◽  
Nicholas Titiloye ◽  
Ernest Adjei ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Case Control Study ◽  
Reproductive Factors ◽  
Population Based ◽  
Case Control ◽  
Ghanaian Women ◽  
Control Study

The J-shaped Association Between Alcohol Consumption and Breast Cancer: A Case-Control Study

2014 ◽  
Vol 10 (2) ◽  
pp. 120-127
Author(s):  
Niki Mourouti ◽  
Meropi Kontogianni ◽  
Christos Papavagelis ◽  
Theodora Psaltopoulou ◽  
Petrini Plytzanopoulou ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Alcohol Consumption ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals A case–control study in France showing that a pro-inflammatory diet is associated with a higher risk of breast cancer

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Mariem Hajji-Louati ◽  
Emilie Cordina-Duverger ◽  
Nasser Laouali ◽  
Francesca-Romana Mancini ◽  
Pascal Guénel
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Odds Ratio ◽  
Hormone Receptors ◽  
Case Control Study ◽  
Breast Cancer Subtype ◽  
Case Control ◽  
Tumor Subtype ◽  
Control Study

AbstractDietary regimens promoting inflammatory conditions have been implicated in breast cancer development, but studies on the association between pro-inflammatory diet and breast cancer risk have reported inconsistent results. We investigated the association between the inflammatory potential of diet and breast cancer risk in a case–control study in France including 872 breast cancer cases and 966 population controls. All women completed a food frequency questionnaire that was used to compute a Dietary Inflammatory Index (DII) based on the inflammatory weight of 33 dietary components. The DII ranged from a median of − 3.22 in the lowest quartile (anti-inflammatory) to + 2.96 in the highest quartile (pro-inflammatory). The odds ratio contrasting quartile 4 to quartile 1 was 1.31 (95% CI 1.00, 1.73; p-trend = 0.02). Slightly higher odds ratios were observed in post-menopausal women, particularly those with body mass index > 25 kg/m2 (odds ratio 1.62; 95% CI 0.92, 2.83; p-trend = 0.02), and among ever smokers (odds ratio 1.71; 95% CI 1.11, 2.65; p-trend 0.01). The analyses by breast cancer subtype showed that the DII was associated with breast tumors that expressed either the estrogen (ER) or progesterone (PR) hormone receptors or the Human Epidermal Growth Factor Receptor-2 (HER2), but no association was seen for the triple negative breast tumor subtype. Our results add further evidence that a pro-inflammatory diet is associated with breast cancer risk with possible effect variation according to tumor subtype.

scholarly journals Association between dietary phytochemical index and breast cancer: a case–control study

Breast Cancer ◽  
2021 ◽  
Author(s):  
Seyed Mojtaba Ghoreishy ◽  
Azadeh Aminianfar ◽  
Sanaz Benisi-Kohansal ◽  
Leila Azadbakht ◽  
Ahmad Esmaillzadeh
Keyword(s):  
Breast Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Control Study
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