RETRACTED: Folic acid mediated endocytosis enhanced by modified multi stimuli nanocontainers for cancer targeting and treatment: Synthesis, characterization, in-vitro and in-vivo evaluation of therapeutic efficacy

2020 ◽  
Vol 55 ◽  
pp. 101481
Author(s):  
E.K. Efthimiadou ◽  
P. Lelovas ◽  
E. Fragogeorgi ◽  
N. Boukos ◽  
V. Balafas ◽  
...  
Keyword(s):  
Folic Acid ◽  
Therapeutic Efficacy ◽  
Cancer Targeting ◽  
In Vivo Evaluation

Novel folate-targeted docetaxel-loaded nanoparticles for tumour targeting: in vitro and in vivo evaluation

RSC Advances ◽  
2016 ◽  
Vol 6 (69) ◽  
pp. 64306-64314 ◽  
Author(s):  
M. H. Han ◽  
Z. T. Li ◽  
D. D. Bi ◽  
Y. F. Guo ◽  
H. X. Kuang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Folic Acid ◽  
Cancer Therapy ◽  
Targeted Delivery ◽  
Tumour Targeting ◽  
Breast Cancer Therapy ◽  
In Vivo Evaluation ◽  
Targeted Delivery System

Cholesterol-PEG1000-FA (folic acid) was synthesized as a stabilizer to encapsulate DTX, for the construction of a promising targeted delivery system for breast cancer therapy.

scholarly journals Future outlook hydrodynamic drug delivery system of solid oral dosage form: Review

2021 ◽  
Vol 6 (3) ◽  
pp. 96-101
Author(s):  
Akhilesh Kumar Singh ◽  
Neeraj Sharma
Keyword(s):  
Drug Delivery ◽  
Therapeutic Efficacy ◽  
Dosage Form ◽  
In Vitro Study ◽  
Local Effect ◽  
Oral Dosage ◽  
In Vivo Evaluation ◽  
Absorption Window

Over the last few years, therapeutic efficacy of drugs that have poor bioavailability or narrow absorption window have challenged the pharmaceutical industry. In this framework, many Hydrodynamic Balance System (HBS) also known as Gastro retentive dosage forms (GRDFs) have been used to enhance the therapeutic efficacy of drugs. Such drug have a narrow absorption window, are unstable at higher pH, are soluble in acidic conditions, and are local effect in the gastric-part. The drug development with recent technology of various novel polymeric-based gastroretentive drug delivery technologies that may regulate the bioavailability and extend time of therapeutic efficacy of such drugs. Our focus on the significance of in vitro study and in vivo evaluation parameters of various HBS drugs along with their applications.  This study provides a promising platform for advantages and guide formulation of HBS dosage form were covered in detail.

In Vitro and in Vivo Evaluation of an Innocuous Drug Cocktail To Improve the Quality of Folic Acid Targeted Nuclear Imaging in Preclinical Research

2013 ◽  
Vol 10 (3) ◽  
pp. 967-974 ◽  
Author(s):  
Cristina Müller ◽  
Josefine Reber ◽  
Claudia Schlup ◽  
Christopher P. Leamon ◽  
Roger Schibli
Keyword(s):  
Folic Acid ◽  
Nuclear Imaging ◽  
Drug Cocktail ◽  
Preclinical Research ◽  
In Vivo Evaluation

Paclitaxel-Loaded, Folic-Acid-Targeted and TAT-Peptide-Conjugated Polymeric Liposomes: In Vitro and In Vivo Evaluation

2010 ◽  
Vol 27 (9) ◽  
pp. 1914-1926 ◽  
Author(s):  
Peiqi Zhao ◽  
Hanjie Wang ◽  
Man Yu ◽  
Shuzhen Cao ◽  
Fei Zhang ◽  
...  
Keyword(s):  
Folic Acid ◽  
Tat Peptide ◽  
In Vivo Evaluation ◽  
Polymeric Liposomes

Paclitaxel loaded folic acid targeted nanoparticles of mixed lipid-shell and polymer-core: In vitro and in vivo evaluation

2012 ◽  
Vol 81 (2) ◽  
pp. 248-256 ◽  
Author(s):  
Peiqi Zhao ◽  
Hanjie Wang ◽  
Man Yu ◽  
Zhenyu Liao ◽  
Xianhuo Wang ◽  
...  
Keyword(s):  
Folic Acid ◽  
In Vivo Evaluation ◽  
Targeted Nanoparticles
Sign in / Sign up

Export Citation Format

Share Document