Association of periodontitis with microvascular complications of diabetes mellitus: A nationwide cohort study

We are all aware of the macrovascular and microvascular complications of diabetes mellitus but till date diabetic striatopathy has been under reported as a complication of uncontrolled diabetes in patients presenting with hemichorea/hemi ballism. We are presenting a case of hemichorea in a case of uncontrolled diabetes mellitus as it is a rare association.

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Serum magnesium levels in newly diagnosed type 2 diabetes mellitus and its relation with microvascular complications of diabetes

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20201926 ◽

2020 ◽

Vol 8 (5) ◽

pp. 1779

Author(s):

Vinay Bhardwaj ◽

Madan Lal Kaushik

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Microvascular Complications ◽

Serum Magnesium ◽

P Value ◽

Diabetic Patients ◽

Newly Diagnosed ◽

Complications Of Diabetes

Background: Prevalence of hypomagnesaemia is significantly higher in diabetic patients with microvascular complications compared to diabetics with no microvascular complications. The aim of this study is to measure levels of serum magnesium in patients with newly diagnosed type 2 diabetes mellitus and study its association with the presenting microvascular complications.Methods: This was hospital based, one year cross-sectional study carried out in Department of Medicine, IGMC Shimla in patients with newly diagnosed type 2 diabetes mellitus. Total 53 patients were enrolled in this study who presented in medicine OPD or admitted in medicine ward.Results: Serum Magnesium value of the patients ranged from 1.20-3.0 mg/dl with mean value of 1.9±0.3 mg/dl. Fourteen patients (26.4%) had hypomagnesaemia. A total of 34 (64.2%) patients presented with complications of diabetes in which proteinuria was present in 34 (64.2%), retinopathy in 4 (7.5%) and neuropathy in 1 (1.9%). Fourteen (41.2%) patients with hypomagnesaemia presented with complications of diabetes (p value=0.003). 34 (64.2%) patients presented with proteinuria out of which 14 (41.2%) patients had hypomagnesaemia while 20 (58.8%) had normomagnesaemia (p=0.03). One (1.9%) patient had neuropathy and hypomagnesaemia was also present in this patient (p=0.6). Four patients (7.5%) presented with retinopathy out of which 3 (5.7%) had hypomagnesaemia while 1 (1.9%) had normomagnesaemia.Conclusions: Hypomagnesaemia is associated with microvascular complications of diabetes. Also there is statistically significant relationship between proteinuria and hypomagnesaemia in patients with newly diagnosed type 2 diabetes mellitus.

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OR14-6 The Role of the Angiopoietin-Tie2 Pathway in Microvascular Complications of Diabetes Mellitus

Journal of the Endocrine Society ◽

10.1210/js.2019-or14-6 ◽

2019 ◽

Vol 3 (Supplement_1) ◽

Author(s):

Mitchell Brigell ◽

Steve Pakola ◽

Barbara Withers ◽

Laura Gambino ◽

Kevin Peters

Keyword(s):

Diabetes Mellitus ◽

Microvascular Complications ◽

Complications Of Diabetes

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Microvascular Complications of Diabetes Mellitus

Principles of Diabetes Mellitus ◽

10.1007/978-1-4757-6260-0_17 ◽

2004 ◽

pp. 317-328

Author(s):

Vincent Yen

Keyword(s):

Diabetes Mellitus ◽

Microvascular Complications ◽

Complications Of Diabetes

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Microvascular Complications of Diabetes Mellitus: Focus on Diabetic Retinopathy (DR) and Diabetic Foot Ulcer (DFU)

10.5772/intechopen.96548 ◽

2021 ◽

Author(s):

Ana Maria Dascalu ◽

Dragos Serban ◽

Nikolaos Papanas ◽

Peter Kempler ◽

Manfredi Rizzo ◽

...

Keyword(s):

Diabetes Mellitus ◽

Diabetic Retinopathy ◽

Diabetic Foot ◽

Microvascular Complications ◽

Foot Ulcer ◽

Vitreoretinal Surgery ◽

Diabetic Foot Ulcer ◽

Complications Of Diabetes ◽

Microvascular Changes ◽

Diabetic Foot Lesions

Diabetic retinopathy and diabetic foot ulcer are the most frequent, but also the most disabling complications of diabetes mellitus, with a sinister impact on patients’ quality of life. Microvascular changes related to the deleterious effect of chronic hyperglycemia play an important role in the pathophysiology of both clinical entities by multiple molecular pathways. Vision-threating diabetic retinopathy may be treated by laser photocoagulation, anti-vascular endothelial growth factor (VEGF) agents and vitreoretinal surgery. Diabetic foot lesions are best treated by revascularization if needed, off-loading, infection control and therapeutic adjuncts (e.g. special dressings). Treatment should ideally be offered by a multidisciplinary expert team. Prevention and early detection, along with adequate control of glucose, lipids and arterial hypertension are of paramount importance to avoid and mitigate these fearful complications.

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