A comparative evaluation on the voltammetric behavior of boron-doped diamond (BDD) and glassy carbon (GC) electrodes in different electrolyte media

2010 ◽  
Vol 642 (1) ◽  
pp. 69-74 ◽  
Author(s):  
V. Suryanarayanan ◽  
M. Noel
2018 ◽  
Vol 18 (7) ◽  
pp. 4551-4558 ◽  
Author(s):  
Paulo Vinicius F. da Costa ◽  
Rejane Maria P. da Silva ◽  
Hugo B Suffredini ◽  
Wendel A Alves

2012 ◽  
Vol 31 (2) ◽  
pp. 195 ◽  
Author(s):  
Sachin Saxena ◽  
Ratnanjali Shrivastava ◽  
Soami P. Satsangee

The electrochemical behavior of the asthma drug doxofylline was studied at a boron-doped diamond electrode in BR buffer (pH 3.8) by square-wave voltammetry. Cyclic voltammetry revealed the oxidation of doxofylline as an irreversible diffusion-controlled process. The oxidation mechanism was proposed and the drug was studied in the presence of solubilized systems like Tween-20 (T-20), sodium dodecyl sulfate (SDS), Triton X-100 (TTN), dioxane (DO), dimethylformamide (DMF), diethyl ether (DEE), benzene and methanol (MeOH). Comparison of the current responses in the solution system explained the sensitivity of the boron-doped diamond electrode (BDDE) with a three-fold increase in the current value compared to that of a glassy carbon electrode (GCE) at a fixed concentration of doxofylline. Peak current values varied linearly with increasing concentration and the LOD and LOQ were found to be 3.48 and 10.56 µg/ml, respectively. This method was employed to investigate doxofylline in the pharmaceutical formulation.


2019 ◽  
Vol 19 (7) ◽  
pp. 4116-4122
Author(s):  
Vadivel Selvamani ◽  
Venkatachalam Rajagopal ◽  
Noel Nesakumar ◽  
David Velayutham ◽  
Vembu Suryanarayanan

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