Voltammetric behavior and determination of the bronchodilator doxofylline at a boron-doped diamond electrode

The electrochemical behavior of the asthma drug doxofylline was studied at a boron-doped diamond electrode in BR buffer (pH 3.8) by square-wave voltammetry. Cyclic voltammetry revealed the oxidation of doxofylline as an irreversible diffusion-controlled process. The oxidation mechanism was proposed and the drug was studied in the presence of solubilized systems like Tween-20 (T-20), sodium dodecyl sulfate (SDS), Triton X-100 (TTN), dioxane (DO), dimethylformamide (DMF), diethyl ether (DEE), benzene and methanol (MeOH). Comparison of the current responses in the solution system explained the sensitivity of the boron-doped diamond electrode (BDDE) with a three-fold increase in the current value compared to that of a glassy carbon electrode (GCE) at a fixed concentration of doxofylline. Peak current values varied linearly with increasing concentration and the LOD and LOQ were found to be 3.48 and 10.56 µg/ml, respectively. This method was employed to investigate doxofylline in the pharmaceutical formulation.

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Voltammetric behavior of I2/2I− redox system on boron-doped diamond electrode in various media and its utilization for the indirect detection of tin(II)

Journal of Electroanalytical Chemistry ◽

10.1016/j.jelechem.2015.10.015 ◽

2015 ◽

Vol 758 ◽

pp. 46-53 ◽

Cited By ~ 3

Author(s):

Zuzana Chomisteková ◽

Eva Culková ◽

Ján Vojtko ◽

Roman Brescher ◽

Peter Tomčík

Keyword(s):

Redox System ◽

Indirect Detection ◽

Boron Doped Diamond ◽

Diamond Electrode ◽

Boron Doped ◽

Boron Doped Diamond Electrode ◽

Voltammetric Behavior

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A Simple Approach to Simultaneous Electroanalytical Quantification of Acetaminophen and Tramadol Using a Boron‐doped Diamond Electrode in the Existence of Sodium Dodecyl Sulfate

Electroanalysis ◽

10.1002/elan.201900452 ◽

2019 ◽

Vol 32 (2) ◽

pp. 429-436 ◽

Cited By ~ 3

Author(s):

Oruç Yunusoğlu ◽

Shabnam Allahverdiyeva ◽

Yavuz Yardım ◽

Zühre Şentürk

Keyword(s):

Sodium Dodecyl Sulfate ◽

Sodium Dodecyl ◽

Simple Approach ◽

Boron Doped Diamond ◽

Diamond Electrode ◽

Boron Doped ◽

Boron Doped Diamond Electrode ◽

Dodecyl Sulfate

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Voltammetric behavior of benzo[a]pyrene at boron-doped diamond electrode: A study of its determination by adsorptive transfer stripping voltammetry based on the enhancement effect of anionic surfactant, sodium dodecylsulfate

Talanta ◽

10.1016/j.talanta.2011.04.005 ◽

2011 ◽

Vol 85 (1) ◽

pp. 441-448 ◽

Cited By ~ 34

Author(s):

Yavuz Yardım ◽

Abdulkadir Levent ◽

Ertuğrul Keskin ◽

Zühre Şentürk

Keyword(s):

Anionic Surfactant ◽

Sodium Dodecylsulfate ◽

Stripping Voltammetry ◽

Enhancement Effect ◽

Boron Doped Diamond ◽

Diamond Electrode ◽

Boron Doped ◽

Boron Doped Diamond Electrode ◽

Voltammetric Behavior

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Voltammetric determination of natamycin using a cathodically pretreated boron-doped diamond electrode in the presence of sodium dodecyl sulfate

Microchemical Journal ◽

10.1016/j.microc.2020.105570 ◽

2020 ◽

Vol 159 ◽

pp. 105570

Author(s):

Katarzyna Mielech-Łukasiewicz ◽

Marta Leoniuk

Keyword(s):

Sodium Dodecyl Sulfate ◽

Sodium Dodecyl ◽

Voltammetric Determination ◽

Boron Doped Diamond ◽

Diamond Electrode ◽

Boron Doped ◽

Boron Doped Diamond Electrode ◽

Dodecyl Sulfate

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Voltammetric behavior of rutin at a boron-doped diamond electrode. Its electroanalytical determination in a pharmaceutical formulation

Open Chemistry ◽

10.2478/s11532-013-0292-6 ◽

2013 ◽

Vol 11 (10) ◽

pp. 1674-1681 ◽

Cited By ~ 8

Author(s):

Pınar Pınar ◽

Yavuz Yardım ◽

Zühre Şentürk

Keyword(s):

Stripping Voltammetry ◽

Adsorptive Stripping Voltammetry ◽

Cyclic Voltammograms ◽

Boron Doped Diamond ◽

Diamond Electrode ◽

Boron Doped ◽

Irreversible Oxidation ◽

Boron Doped Diamond Electrode ◽

Voltammetric Behavior ◽

First Time

AbstractThis paper examined for the first time, the possibilities of the usage of a boron-doped diamond electrode for the redox behavior of rutin using cyclic and adsorptive stripping voltammetry. The cyclic voltammograms showed a pair of redox peaks at lower potentials followed by an irreversible oxidation peak at higher positive potential. Using square-wave adsorptive stripping voltammetry, the compound yielded a well-defined voltammetric response in Britton-Robinson buffer, pH 4.0 at +0.48 V (vs. Ag/AgCl) (after 60 s accumulations at a fixed potential of 0.2 V). The calibration curve was linear in the concentration range from 0.01 µg mL−1 to 0.1 µg mL−1 (1.64×10−8 M − 1.64×10−7 M). A detection limit of 0.0017 µg mL−1 (2.78×10−9 M) was observed without any chemical modifications and electrochemical surface pretreatments. As an example, the practical applicability of boron-doped diamond electrode was tested with the measurement of rutin in dietary supplement products.

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Determination of tramadol in pharmaceutical forms and urine samples using a boron-doped diamond electrode

Journal of the Serbian Chemical Society ◽

10.2298/jsc190906138k ◽

2020 ◽

Vol 85 (7) ◽

pp. 923-937

Author(s):

Ertuğrul Keskin ◽

Shabnam Allahverdiyeva ◽

Esma Şeyho ◽

Yavuz Yardim

Keyword(s):

Sodium Dodecyl ◽

Pharmaceutical Formulations ◽

Open Circuit ◽

Urine Samples ◽

Oxidation Peak ◽

Boron Doped Diamond ◽

Diamond Electrode ◽

Boron Doped ◽

Boron Doped Diamond Electrode

The present work describes the electroanalytical investigation and a novel voltammetric method for the cheap, fast and simple quantification of tramadol (TRH) using a boron-doped diamond electrode. TRH displayed one well-defined, irreversible and adsorption-controlled oxidation peak at about 1.58 V (vs. Ag/AgCl) in Britton?Robinson buffer (BR, 0.1 mol L-1, pH 3.0) using the cyclic voltammetry technique. The voltammetric responses of the oxidation peaks are dependent on pH and their sensitivity was significantly enhanced in the presence of surfactant media (sodium dodecyl sulphate, SDS). Under the optimized experiment conditions, employing the square-wave stripping mode, it was found that there was an excellent correlation between oxidation peak current and the TRH concentration in the range 0.25 to 50.0 ?g mL-1 (8.34?10-7?1.67?10-4 mol L-1), with a detection limit of 0.072 ?g mL-1 (2.40?10-7 mol L-1) in 0.1 mol L-1 BR buffer (pH 3.0) solution comprising 8?10-4 mol L-1 SDS at 1.52 V (after 30 s accumulation at open-circuit conditions). The developed approach could be used for the quantification of TRH in pharmaceutical formulations and spiked human urine samples with acceptable recoveries.

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