Evaluation of the diuretic activity in two Mexican medicinal species: Selaginella nothohybrida and Selaginella lepidophylla and its effects with ciclooxigenases inhibitors

2015 ◽  
Vol 163 ◽  
pp. 167-172 ◽  
Author(s):  
María I. Aguilar ◽  
Wendy V. Benítez ◽  
Arturo Colín ◽  
Robert Bye ◽  
Ramiro Ríos-Gómez ◽  
...  
Planta Medica ◽  
2014 ◽  
Vol 80 (10) ◽  
Author(s):  
MI Aguilar ◽  
WV Benítez ◽  
A Colín ◽  
A Tovar ◽  
F Calzada

Author(s):  
AK Das ◽  
F Ahmed ◽  
NN Biswas ◽  
S Dev ◽  
MM Masud

Dhaka Univ. J. Pharm. Sci. Vol.4(1) 2005 The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website


2018 ◽  
Vol 25 (23) ◽  
pp. 2627-2636 ◽  
Author(s):  
Vincenzo Calderone ◽  
Alma Martelli ◽  
Eugenia Piragine ◽  
Valentina Citi ◽  
Lara Testai ◽  
...  

In the last four decades, the several classes of diuretics, currently available for clinical use, have been the first line option for the therapy of widespread cardiovascular and non-cardiovascular diseases. Diuretic drugs generally exhibit an overall favourable risk/benefit balance. However, they are not devoid of side effects. In particular, all the classes of diuretics cause alteration of potassium homeostasis. <p> In recent years, understanding of the physiological role of the renal outer medullary potassium (ROMK) channels, has shown an intriguing pharmacological target for developing an innovative class of diuretic agents: the ROMK inhibitors. This novel class is expected to promote diuretic activity comparable to (or even higher than) that provided by the most effective drugs used in clinics (such as furosemide), with limited effects on potassium homeostasis. <p> In this review, the physio-pharmacological roles of ROMK channels in the renal function are reported, along with the most representative molecules which have been currently developed as ROMK inhibitors.


Plants ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 584
Author(s):  
Nadia Las Heras Las Heras Etayo ◽  
Félix Llamas ◽  
Carmen Acedo

The species Chiliadenus glutinosus (L.) Fourr. has a large number of therapeutic uses reported in the traditional Spanish medicine. The growing interest in preserving the ethnopharmacological knowledge related to the botanical diversity existing in Spain and the interest in achieving scientific validation of the therapeutic properties of medicinal species has led to the development of this study. To do it, all the known medicinal uses of Ch. glutinosus in Spain were compiled, then an exhaustive bibliographic research on its chemical composition was carried out, and finally, an in silico validation of the bioactive phytochemicals present in a higher proportion in the essential oil of Ch. glutinosus: camphor, borneol, lucinone, glutinone, quercetin, kutdtriol, and kaempferol; in an attempt to justify the reported traditional uses of the species. It was found that much of the traditional medicinal uses of Ch. glutinosus, along with the biological activity of its phytochemicals, are supported by scientific evidence. The results place this species in a prominent position to initiate possible lines of research to develop new, more effective drugs and improve therapies to treat conditions and diseases that affect the different organic systems of the human being.


2021 ◽  
Vol 57 (1) ◽  
pp. 133-135
Author(s):  
N. I. Romanenko ◽  
O. P. Dolhikh ◽  
D. G. Ivanchenko ◽  
I. B. Samura ◽  
A. A. Goloborodko ◽  
...  

2011 ◽  
Vol 3 (2) ◽  
Author(s):  
Ying Zhang ◽  
Zhenya Zhang ◽  
Yingnan Yang ◽  
Yuepeng Wang ◽  
Xiaoyan Zu ◽  
...  

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