Therapeutic effects of andiroba (Carapa guianensis Aubl) oil, compared to low power laser, on oral mucositis in children underwent chemotherapy: A clinical study

2021 ◽  
Vol 264 ◽  
pp. 113365
Author(s):  
Artur dos Santos Soares ◽  
Ana Márcia Viana Wanzeler ◽  
Gabriel Henrique Soares Cavalcante ◽  
Elsa Maria da Silva Barros ◽  
Rita de Cássia Matos Carneiro ◽  
...  
1990 ◽  
Vol 11 (Supplement) ◽  
pp. 493-497
Author(s):  
Hideki Shinohara ◽  
Yoshifusa Shinohara ◽  
Takashi Hirano ◽  
Masanori Ishii ◽  
Mituru Ishitsuki ◽  
...  

Author(s):  
Isabela Américo Eutran da Silva ◽  
Flavia Mota de Souza ◽  
Gabriel Araújo da Silva ◽  
Karin Sá Fernandes

Blood ◽  
2006 ◽  
Vol 109 (5) ◽  
pp. 2250-2255 ◽  
Author(s):  
Héliton Spíndola Antunes ◽  
Alexandre Mello de Azevedo ◽  
Luiz Fernando da Silva Bouzas ◽  
Carlos Alberto Esteves Adão ◽  
Claudia Tereza Pinheiro ◽  
...  

Abstract We investigated the clinical effects of low-power laser therapy (LPLT) on prevention and reduction of severity of conditioning-induced oral mucositis (OM) for hematopoietic stem cell transplantation (HSCT). We randomized 38 patients who underwent autologous (AT) or allogeneic (AL) HSCT. A diode InGaAlP was used, emitting light at 660 nm, 50 mW, and 4 J/cm2, measured at the fiberoptic end with 0.196 cm2 of section area. The evaluation of OM was done using the Oral Mucositis Assessment Scale (OMAS) and the World Health Organization (WHO) scale. In the LPLT group, 94.7% of patients had an OM grade (WHO) lower than or equal to grade 2, including 63.2% with grade 0 and 1, whereas in the controls group, 31.5% of patients had an OM grade lower than or equal to grade 2 (P < .001). Remarkably, the hazard ratio (HR) for grades 2, 3, and 4 OM was 0.41 (range, 0.22-0.75; P = .002) and for grades 3 and 4 it was 0.07 (range, 0.11-0.53; P < .001). Using OMAS by the calculation of ulcerous area, 5.3% of the laser group presented with ulcers of 9.1 cm2 to 18 cm2, whereas 73.6% of the control group presented with ulcers from 9.1 cm2 to 18 cm2 (P = .003). Our results indicate that the use of upfront LPLT in patients who have undergone HSCT is a powerful instrument in reducing the incidence of OM and is now standard in our center.


2013 ◽  
Vol 79 (6) ◽  
pp. 792 ◽  
Author(s):  
Niedson José de Siqueira Medeiros ◽  
Nadson Frederico de Siqueira Medeiros ◽  
Carla Caroline Medeiros dos Santos ◽  
Georgia Veloso Ulisses Parente ◽  
Januse Nogueira de Carvalho

2012 ◽  
Vol 8 (Issue 3-4) ◽  
pp. 44-48
Author(s):  
Magda Mostafa ◽  
M. Abdelrahman ◽  
Wesam Elshrief ◽  
Awatef L. ◽  
Soheir S. ◽  
...  

2020 ◽  
Vol 48 ◽  
Author(s):  
Paulo Geovane De Cantuário Ferreira ◽  
Leonardo Inocêncio Cunha ◽  
Pâmella Gomes Rabelo ◽  
Any Tâmara da Silva Rocha ◽  
André Giarola Boscarato ◽  
...  

Background: Skin wounds are among the most common cases in small animals, highlighting the importance of alternative therapies as an aid to the healing process. These include ozone, which has a bactericidal and immunomodulatory action; the low power laser that determines photodynamic changes triggering metabolism elevation; and the use of medicinal plants, in which several herbal medicines has been mentioned in research relating their benefits to wound healing in humans and animals. Thus, it aims to report the case of a dog submitted to these treatments due to chronic wound due to bite.Case: A 6-year-old canine, female, mixed-breed, 8 kg, with a perforating wound in the left anterior limb in the scapular and humeral region, caused by trauma from the bite of another dog, previously treated, without clinical improvement, has been attended presenting apathy, increased body temperature (40.1°C), difficulty in walking and inability to support the injured limb, which was swollen, hyperemic, with elevated temperature, absence of hair, elevated pain sensitivity and presence of 2 circular lesions, approximately 2 cm in diameter, caused by trauma, and others of size between 0.5 and 1 cm in diameter, which appeared during the course of the disease, characterized as fistulas, through which there was drainage of characteristic fluid exudative and purulent discharge. It was collected blood sample for blood count and purulent material through sterile swab for culture and antibiogram. Systemic treatment with ceftiofur, dipyrone, meloxican and topical cleaning of the wounds with hydrogen peroxide and physiological solution; dimethyl sulfoxide ointment, and hot compresses was chosen. After seven days, the animal showed significant general clinical improvement and in the limb, it was observed: decreased edema, hyperemia, hyperthermia and secretions, with no pus. Only local treatment was recommended, with cleansing of the skin lesions, with physiological solution, chlorhexidine and healing gel made of herbal medicine: chitosan, aloe vera, marigold, sunflower oil and barbatimao. After 21 days of treatment, the injured limb showed consecutive clinical improvement, with epithelialization of the smaller diameter lesions. Low-level laser and ozone therapy was instituted, totaling three initial sessions every five days and one last session 14 days after the third. After the four sessions the animal was discharged, presenting absence of the previously reported alterations, besides the total re-epithelialization of the lesions and hair growth. Discussion: The contamination arising from bite can interfere with healing time due to the action of bacterial toxins and inflammatory infiltrates that cause vascular and cellular damage. According to other reports the use of ozone therapy, local and systemic, promoted rapid healing, related to effective decontamination, in a short period of time. Considering the response and quality of tissue repair, due to wound recovery, verifying therapeutic effects of anti-inflammatory action, effective decontamination, stimulation of granulation tissue, epithelialization and repilation of the cutaneous region, it is concluded that topical and systemic ozone therapy, associated with the effect of tissue regeneration by edge revival in chronic lesions, of low power laser and herbal medicine gel, under the conditions of this case, represent satisfactory therapy for the treatment of bite wounds in dogs.


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