Zataria multiflora extract influenced asthmatic patients by improving respiratory symptoms, pulmonary function tests and lung inflammation

Objective: To investigate the relationship between serum values of magnesium and the parameters of the pulmonary function tests (PFT) in patients with chronic asthma. Subjects and Methods: This study recruited 50 patients with chronic stable asthma and 40 healthy individuals as a control group. Data on age, sex, severity of asthma, PFT, and details of drug therapy were obtained from each group. Serum magnesium, potassium, phosphorus, calcium, and sodium levels were also measured. To evaluate differences between groups, the Student t test or Mann-Whitney U test was performed for continuous variables, and the χ2 test for categorical variables. Results: In the asthma group, 10% (n = 9) of the patients had hypomagnesemia and 5.5% (n = 5) had hypophosphatemia. Patients with asthma were divided into two groups: the hypomagnesemic group (n = 9) and the normomagnesemic group (n = 41). Forced expiratory volume in 1 s (FEV1), FEV1%, peak expiratory flow (PEF), and PEF% were lower in the hypomagnesemic group than in the normomagnesemic group (p = 0.02). Multiple logistic regression analysis revealed a statistically significant association between hypomagnesemia and PFT in the hypomagnesemic asthmatic group. The correlations of age with FEV1, FEV1%, PEF, and PEF% were as follows: p = 0.00, r = 0.29; p = 0.00, r = 0.43; p = 0.03, r = 0.22; p = 0.00, r = 0.38; and p = 0.03, r = 0.22, respectively. The correlation of serum magnesium levels with PFT (FEV1, FEV1%, PEF, PEF%) were as follows: p = 0.001, r = 0.29; p = 0.001, r = 0.43; p = 0.03, r = 0.22; and p = 0.001, r = 0.38, respectively. The other electrolytes were within the normal range in both groups. Conclusion: In this study, hypomagnesemia and hypophosphatemia were found to be the most common electrolyte abnormalities in patients with chronic stable asthma. FEV1, FEV1%, PEF, and PEF% were significantly lower in asthmatic patients with hypomagnesemia compared to asthmatic patients with normomagnesemia.

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Respiratory Symptoms and Pulmonary Function tests among Informal Sector Workers Exposed to Wood Dust in Douala, Cameroon

Journal of Allergy & Therapy ◽

10.4172/2155-6121.1000225 ◽

2015 ◽

Vol 06 (06) ◽

Author(s):

Francis NDE ◽

Hugo Mbatchou

Keyword(s):

Pulmonary Function ◽

Informal Sector ◽

Respiratory Symptoms ◽

Pulmonary Function Tests ◽

Wood Dust ◽

Function Tests

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Pulmonary function tests and respiratory symptoms among smokers in the city of mashhad (north east of Iran)

Revista Portuguesa de Pneumologia (English Edition) ◽

10.1016/j.rppnen.2011.09.001 ◽

2011 ◽

Vol 17 (5) ◽

pp. 199-204

Keyword(s):

Pulmonary Function ◽

Respiratory Symptoms ◽

Pulmonary Function Tests ◽

North East ◽

Function Tests ◽

East Of Iran ◽

The City

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Respiratory symptoms and pulmonary function tests in school teachers of Shimla

Lung India ◽

10.4103/0970-2113.44195 ◽

2007 ◽

Vol 24 (1) ◽

pp. 6 ◽

Cited By ~ 2

Author(s):

S Kashyap ◽

A Sharma ◽

D Gupta ◽

PR Mohapatra ◽

P Vaidya

Keyword(s):

Pulmonary Function ◽

Respiratory Symptoms ◽

Pulmonary Function Tests ◽

School Teachers ◽

Function Tests

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Relationship between pulmonary function tests, sputum eosinophilia and total serum IgE levels among asthmatic patients in Duhok, Iraq

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20202239 ◽

2020 ◽

Vol 8 (6) ◽

pp. 2033

Author(s):

Hamdia Yousif Issa ◽

Ali A. Ramadhan ◽

Abdulazeez S. Safo ◽

Omar A. M. Al Habib

Keyword(s):

Pulmonary Function ◽

Severe Asthma ◽

Inflammatory Markers ◽

Pulmonary Function Tests ◽

Asthma Severity ◽

Total Serum ◽

Serum Ige ◽

Sputum Eosinophilia ◽

Asthmatic Patients ◽

Function Tests

Background: Bronchial asthma is a disease characterized by reversible airway obstruction, airway inflammation; and hyper-responsiveness. The prevalence of asthma is high, and both its prevalence and burden have increased over the last several decades. The study of inflammatory markers has implications for the appropriate management of this disease. Inflammatory markers has implications for the appropriate management of this disease. Objective of the study is to determine the correlation between asthma severity using pulmonary function tests with sputum eosinophilia and total serum IgE levels.Methods: This case-control study was conducted from March 2017 to September 2018 in the respiratory unit of Azadi general teaching hospital. It included 42 asthmatic patients and 18 healthy subjects. They underwent pulmonary function tests and measurement of total serum IgE levels. Induced sputum was done for asthmatic patients.Results: The age of asthmatic patients ranged from 16-70 years (mean 42±19 years). The asthmatic patient’s female: male ratio was 1.8. Mild asthma was the most common severity group (N=18, 43%) followed by moderate asthma (N=14, 33%) then severe asthma (N=10, 24%). Abnormal sputum eosinophilia (≥3%) was detected in 90% of severe asthma (N=9) compared to 36% in moderate asthma (N=5) and 5.6% in mild asthma (N=1). There was significant statistical association between asthma severity and sputum eosinophilia (p=0.00004). The association between asthma severity and total serum IgE levels was highly significant (p<0.0000) with levels of total serum IgE increasing as the severity of asthma increases.Conclusions: Severe asthma is the least common severity group in this study. Both abnormal sputum eosinophilia and total serum IgE levels are associated with the severity of asthma.

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