Therapeutic effect of Patrinia villosa on TNBS-induced ulcerative colitis via metabolism, vitamin D receptor and NF-κB signaling pathways

2022 ◽  
pp. 114989
Author(s):  
Jiaqi Wang ◽  
Xin Wang ◽  
Xiande Ma ◽  
Baoli Xu ◽  
Lijiang Chen ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Vitamin D ◽  
Signaling Pathways ◽  
Therapeutic Effect ◽  
Vitamin D Receptor

Vitamin D Receptor Level in Biopsy Specimen of Patients with Ulcerative Colitis: Results from a Center in Western Anatolia

2018 ◽  
Vol 110 (3) ◽  
pp. 276-280 ◽  
Author(s):  
Adil Coskun ◽  
Irfan Yavasoglu ◽  
Ibrahim Meteoglu ◽  
Mustafa Unubol ◽  
Burak Yasar ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Vitamin D ◽  
Vitamin D Receptor ◽  
Biopsy Specimen ◽  
Western Anatolia ◽  
Receptor Level

Topical Vitamin D Receptor Antagonist/Partial-Agonist Treatment Induces Epidermal Hyperproliferation via RARγ Signaling Pathways

Dermatology ◽  
2020 ◽  
pp. 1-7
Author(s):  
Renata Lucas ◽  
Johanna Mihály ◽  
Janine Gericke ◽  
Angel R. de Lera ◽  
Susana Alvarez ◽  
...  
Keyword(s):  
Vitamin D ◽  
Receptor Antagonist ◽  
Signaling Pathways ◽  
Vitamin D Receptor ◽  
Partial Agonist

The BsmI Vitamin D Receptor Gene Polymorphism Is Associated with Ulcerative Colitis in Jewish Ashkenazi Patients

2004 ◽  
Vol 8 (4) ◽  
pp. 417-420 ◽  
Author(s):  
Rivka Dresner-Pollak ◽  
Zvi Ackerman ◽  
Rami Eliakim ◽  
Amir Karban ◽  
Yehuda Chowers ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Vitamin D ◽  
Gene Polymorphism ◽  
Vitamin D Receptor ◽  
Receptor Gene ◽  
Vitamin D Receptor Gene ◽  
Receptor Gene Polymorphism

scholarly journals The Functional Consequences of Cross-talk between the Vitamin D Receptor and ERK Signaling Pathways Are Cell-specific

2004 ◽  
Vol 279 (45) ◽  
pp. 47298-47310 ◽  
Author(s):  
Ramesh Narayanan ◽  
Veronica A. Tovar Sepulveda ◽  
Miriam Falzon ◽  
Nancy L. Weigel
Keyword(s):  
Vitamin D ◽  
Signaling Pathways ◽  
Vitamin D Receptor ◽  
Cross Talk ◽  
Erk Signaling ◽  
Functional Consequences

scholarly journals Role of TaqI-Genetic Polymorphism of Vitamin D Receptor Gene in Bone Metabolism in Children with Inflammatory Bowel Disease

2017 ◽  
Vol 8 (3) ◽  
pp. 111-119
Author(s):  
Tatiana V Gabrusskaia ◽  
Michail M Kostik ◽  
Yulia A Nasyhova ◽  
Maria O Revnova ◽  
Diana A Kuzmina
Keyword(s):  
Ulcerative Colitis ◽  
Inflammatory Bowel Disease ◽  
Vitamin D ◽  
Bone Metabolism ◽  
Vitamin D Receptor ◽  
Linear Growth ◽  
Receptor Gene ◽  
Vitamin D Receptor Gene ◽  
Vdr Gene ◽  
Inflammatory Bowel

Evaluation of bone mineralization and bone metabolism in children with inflammatory bowel disease (IBD) in accordance with TaqI-polymorphic genotypes of vitamin D receptor (VDR) has been performed in this study. 83 children (38 girls and 54 boys) with IBD (60 with Crohn’s disease, 23 with ulcerative colitis) have been included in the study. Mean age was 13.0 years (11.0; 15.5). All patients have active phase of the disease. Bone mineral density (BMD) of lumbar spine (DEXA) have been assessed in all children. Level of serum osteocalcin (OC) as a marker of osteosynthesis, C-terminal telopeptides (CTT) as a marker of osteoresorbtion, parathyroid hormone (PTH), serum calcium, phosphorus, alkaline phosphatase and 25(OH) vitamin D was measured to evaluate bone metabolism. Molecular-genetic tests: analysis of TaqI (rs731236) polymorphism of vitamin D receptor gene (VDR) was perfomed by polymerase chain reaction with following restriction analysis. Association between molecular markers of VDR gene and bone metabolism and mineralization disturbances have been found. TT genotype of VDR gene was associated with tendency to decrease of linear growth velocity, low linear growth, decrease in osteosynthesis and increase of osteoresorbtion in this group of children. TT-genotype of TaqI-polymorphism of VDR gene can be assessed as a risk factor of bone metabolism disturbances in children with both Crohn’s disease and ulcerative colitis. C allele seems to have protective role in this group.

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