Impact of antibiotic timing relative to percutaneous aspiration on culture positivity rate and clinical outcomes: A retrospective study of patients with pyogenic liver abscess

2021 ◽  
Author(s):  
Keito Shinmoto ◽  
Eiji Hiraoka ◽  
Masao Horiuchi ◽  
Keishiro Sueda ◽  
Rentaro Oda ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Clinical Outcomes ◽  
Liver Abscess ◽  
Pyogenic Liver Abscess ◽  
Percutaneous Aspiration ◽  
Culture Positivity ◽  
Culture Positivity Rate

Clinical Outcomes and Prognostic Factors of Cancer Patients with Pyogenic Liver Abscess

2011 ◽  
Vol 15 (11) ◽  
pp. 2036-2043 ◽  
Author(s):  
Shiuan-Chih Chen ◽  
Yuan-Ti Lee ◽  
Shih-Jei Tsai ◽  
Kuang-Chi Lai ◽  
Chi-Chou Huang ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Cancer Patients ◽  
Clinical Outcomes ◽  
Liver Abscess ◽  
Pyogenic Liver Abscess

scholarly journals Presentation and Management of Pyogenic Liver Abscess in a 23-Week Pregnant Woman

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Beril Yüksel ◽  
Ali Seven ◽  
Suna Kucur ◽  
Ilay Gözükara ◽  
Nadi Keskin
Keyword(s):  
Pregnant Woman ◽  
Liver Abscess ◽  
Wide Spectrum ◽  
Rare Condition ◽  
Pyogenic Liver Abscess ◽  
Abdominal Ultrasound ◽  
Percutaneous Aspiration ◽  
Medical Observation ◽  
Elective Cesarean ◽  
Liver Region

Pyogenic liver abscess during pregnancy is an extremely rare condition. We report a case of 33-year-old, 23-week pregnant woman with pyogenic liver abscess. She was still in the hospital for medical observation of fever, when a sudden episode of tachycardia with a pulse of 210 beats per minute and tachypnea with a respiratory rate of 30 breaths per minute was encountered. At that moment, her fever was 39.6°C (103.28 Fahrenheit). The abdominal ultrasound stated a calcific echogenic mass with a measure of 6 cm in the liver region. Given the sonographic characteristics noted, a liver abscess was suspected. Our case was successfully treated with an ultrasound guided percutaneous aspiration of the abscess and a wide spectrum antibiotic. At 38 weeks of gestation, an elective cesarean delivery was performed. The female neonate weighed 3200 g with APGAR scores of 9 and 9 at the first and fifth minutes, respectively.

scholarly journals Sensitivity Pattern of Gram Negative Bacteria Contaminating Traumatic Wounds: A Retrospective Study in a Tertiary Care Hospital of Kathamandu Valley

2020 ◽  
Vol 19 (2) ◽  
pp. 103-107
Author(s):  
Satya Narayan Suwal ◽  
Sammodavardhana Kaundinnyayana ◽  
Krishna Govinda Prajapati ◽  
Reena Baidya
Keyword(s):  
Retrospective Study ◽  
Antibacterial Agents ◽  
Resistant Bacteria ◽  
Gram Negative Bacteria ◽  
Care Hospital ◽  
Gram Negative ◽  
Accidental Trauma ◽  
Culture Positivity ◽  
Sensitivity Pattern ◽  
Culture Positivity Rate

Introduction: Gram negative bacteria are commonly involved in wound infections and are significantly associated with morbidity and mortality because of increasing resistance to commonly used antibacterial agents. This study aims to evaluate the pattern of antibacterial sensitivity of the gram negative bacteria from wound swabs of accidental trauma cases. Methods: This retrospective study was done by collecting all the culture positive reports for wound swabs of accidental wounds from the microbiology laboratory and analyzing the reports showing growth of gram negative bacteria for frequency of sensitivity to commonly used antibacterial agents. Results: Culture positivity rate was 21.95% with growth of gram negative bacteria in 79.7% of cases. The most commonly isolated organism was Escherichia coli being 41.3% among gram negative isolates. Highly resistant bacteria were E. coli, Klebsiella pneumoniae and Acinetobacter spp. Conclusions: As there is low culture positivity rate for wound swabs obtained before washing the wounds inflicted by accidental trauma, prolonged routine use of prophylactic antibiotic is not justified. Thoroughly washing the wound is very likely to decrease the rate of wound infection further and reduces the need of antibacterial agents. Culture and sensitivity test should guide the treatment when wound is infected because highly resistant gram negative organism may be involved in such cases.

scholarly journals Pyogenic liver abscess: a retrospective study of 208 cases in a single surgery department

HPB ◽  
2018 ◽  
Vol 20 ◽  
pp. S487
Author(s):  
O.A. Nutu ◽  
I. Justo Alonso ◽  
M. García-Conde Delgado ◽  
A.A. Marcacuzco Quinto ◽  
L. Alonso Murillo ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Liver Abscess ◽  
Pyogenic Liver Abscess ◽  
Surgery Department

scholarly journals ABSES HATI PIOGENIK

2012 ◽  
Vol 36 (1) ◽  
pp. 106
Author(s):  
Yusri Dianne Jurnalis ◽  
Delfican Delfican ◽  
Yorva Sayoeti
Keyword(s):  
Liver Abscess ◽  
Clinical Symptoms ◽  
Pyogenic Liver Abscess ◽  
Needle Aspiration ◽  
Surgical Drainage ◽  
Percutaneous Aspiration ◽  
High Grade Fever ◽  
Threatening Condition ◽  
Upper Abdominal ◽  
The Right

AbstrakAbses hati piogenik merupakan suatu kondisi yang berat dan mengancam kehidupan dengan angka mortalitas yang tinggi sehingga membutuhkan diagnostik dan terapi yang akurat. Gejala yang paling sering ditemukan adalah nyeri perut bagian atas, hepatomegali, demam tinggi, mual dan muntah. Gejala ini bervariasi sesuai ukuran abses, keadaan umum pasien, adanya penyakit dasar dan komplikasi. Pada sebagian besar kasus, penyakit dasarnya tidak diketahui. Abses biasanya soliter dan terletak di lobus kanan hati. USG dan CT scan abdomen merupakan sarana diagnostik utama. Abses hati piogenik diterapi dengan aspirasi perkutaneus bersamaan dengan antibiotik. Jika gagal, drainase dengan pembedahan dibutuhkan. Dengan adanya terapi invasif yang minimal seperti aspirasi jarum perkutaneus atau drainase kateter yang dipandu secara radiologis serta ketersediaan antibiotik berspektrum luas, pasien jarang membutuhkan tindakan pembedahan saat ini.Kata kunci : abses hati piogenik, aspirasi perkutaneus, drainase bedahAbstractPyogenic liver abscess (PLA) is a serious, life threatening condition with a high mortality rate that represents a diagnostic and therapeutic challenge. The most common presenting clinical symptoms are upper abdominal pain, tenderness, hepatomegaly, high-grade fever, nausea and vomiting. These features are variable depending upon the size of the abscess, general health of the patient, associated diseases and complications. In majority of the cases, the underlying cause could not be identified. Majority of abscesses are solitary and are noted in the right lobe of liver. USG and CT of the abdomen are the main tools of diagnosis. PLAs are mainly treated by percutaneous aspiration under antibiotic cover. If fails, surgical drainage becomes necessary. However, with the advent of minimally invasive therapy such as image-guided percutaneous needle aspiration or catheter drainage and the availability of broadspectrum antibiotics, patients with PLA nowadays seldom require open surgery for treatment.Key word : pyogenic liver abscess, percutaneous aspiration, surgical drainage

scholarly journals P-L09 Pyogenic Liver Abscess: a Retrospective Study of Patients Presenting to a UK Tertiary Liver Centre

2021 ◽  
Vol 108 (Supplement_9) ◽  
Author(s):  
Emily Sams ◽  
Patricia Duncan ◽  
David O'Reilly ◽  
Giorgio Alessandri ◽  
Craig Parry ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Liver Abscess ◽  
Pyogenic Liver Abscess ◽  
University Hospital ◽  
Western World ◽  
Gallbladder Perforation ◽  
Secondary Source ◽  
Search Term ◽  
Number Of Patients ◽  
Increased Risk

Abstract Background Pyogenic liver abscess (PLA) carries a significant mortality of between 2-12%. The incidence is higher in East Asia than in Western countries, and recent data looking at PLA in western populations is limited. Increasingly, we find that PLA is primary in the liver rather than from a secondary source, even in the western world. The aim of this retrospective study is to analyse data on presentation and outcomes of PLA at a UK tertiary liver centre. Methods Data was collected on patients diagnosed with a PLA and treated at the University Hospital of Wales, Cardiff between December 2010 and December 2020. Patients were identified by searching the Cardiff Liver Unit surgical database and Radiology database using the search term “liver abscess”. Patients with an abscess secondary to gallbladder perforation into the liver were excluded. Data was gathered using the available electronic health records, including  comorbidities, mode of presentation, cause of PLA, microbiology, treatment received (surgical, radiological drainage, or antibiotic therapy), and outcomes. Results There were 86 patients with a median age of 69 (16-91), Male:Female ratio was 2:1. Main symptoms were abdominal pain and fever; 61.6% (n = 53). Treatment was surgical in 49% (n = 42), US guided drainage in 21% (n = 18) and antibiotics only in 30% (n = 26). Mortality was 9.3% (n = 8), with a median age of 76, significantly higher than survivors (p = 0.012). In this group, Male:Female ratio was 7:1; proportion with >2 co-morbidities was 62%, compared with 39% of survivors; and there was a greater delay in diagnosis (average 4 days versus 2 days in survivors), although these factors were not statistically significant. Conclusions PLA is a serious infection that can lead to mortality. Forty percent of patients can present with non-specific symptoms and early imaging in this group is essential for diagnosis. In our cohort, significant number of patients were treated with surgery compared to the literature, with good outcomes.  Although the numbers are small to be statistically significant, delayed diagnosis, multiple comorbidities, and male gender confer an increased risk of mortality, as does advanced age. We conclude that early diagnosis and referral to a Liver centre for opinion or management is essential for optimal outcomes.

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