LB794 Synthesis and biological evaluation of a small molecule library identifies novel anti-skin cancer agents

Journal of Investigative Dermatology ◽

10.1016/j.jid.2021.07.124 ◽

2021 ◽

Vol 141 (9) ◽

pp. B19

Author(s):

S.T. Boateng ◽

T. Roy ◽

R.N. Chamcheu ◽

S. Banang-Mbeumi ◽

A.L. WALKER ◽

...

Keyword(s):

Skin Cancer ◽

Small Molecule ◽

Biological Evaluation ◽

Small Molecule Library ◽

Synthesis And Biological Evaluation

Download Full-text

Synthesis and biological evaluation of a small molecule library of 3rd generation multidrug resistance modulators

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2009.01.072 ◽

2009 ◽

Vol 17 (6) ◽

pp. 2524-2535 ◽

Author(s):

Werner Klinkhammer ◽

Henrik Müller ◽

Christoph Globisch ◽

Ilza K. Pajeva ◽

Michael Wiese

Keyword(s):

Multidrug Resistance ◽

Small Molecule ◽

Biological Evaluation ◽

Small Molecule Library ◽

Synthesis And Biological Evaluation ◽

Resistance Modulators

Download Full-text

Peer Review #1 of "Synthesis and biological evaluation of small molecule modulators of CDK8/Cyclin C complex with phenylaminoquinoline scaffold (v0.1)"

10.7287/peerj.8649v0.1/reviews/1 ◽

2020 ◽

Keyword(s):

Peer Review ◽

Small Molecule ◽

Biological Evaluation ◽

Cyclin C ◽

C Complex ◽

Small Molecule Modulators ◽

Synthesis And Biological Evaluation

Download Full-text

Small-Molecule Inhibitors of 25-Hydroxyvitamin D-24-Hydroxylase (CYP24A1): Synthesis and Biological Evaluation

Journal of Medicinal Chemistry ◽

10.1021/jm5009314 ◽

2014 ◽

Vol 57 (18) ◽

pp. 7702-7715 ◽

Author(s):

Salvatore Ferla ◽

Ahmed S. Aboraia ◽

Andrea Brancale ◽

Christopher J. Pepper ◽

Jinge Zhu ◽

...

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors ◽

Biological Evaluation ◽

Hydroxyvitamin D ◽

25 Hydroxyvitamin D ◽

Synthesis And Biological Evaluation

Download Full-text

Design, Synthesis, and Biological Evaluation of Linear Aliphatic Amine-Linked Triaryl Derivatives as Potent Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction with Promising Antitumor Effects In Vivo

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.0c01329 ◽

2020 ◽

Vol 63 (22) ◽

pp. 13825-13850

Author(s):

Jialin Guo ◽

Longlong Luo ◽

Zhihong Wang ◽

Naijing Hu ◽

Wei Wang ◽

...

Keyword(s):

Programmed Cell Death ◽

Small Molecule ◽

Aliphatic Amine ◽

Biological Evaluation ◽

Antitumor Effects ◽

Design Synthesis ◽

Programmed Cell Death 1 ◽

Synthesis And Biological Evaluation

Download Full-text

Synthesis and biological evaluation of thio-benzodiazepines as novel small molecule inhibitors of the p53–MDM2 protein–protein interaction

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2011.09.043 ◽

2011 ◽

Vol 46 (11) ◽

pp. 5654-5661 ◽

Author(s):

Chunlin Zhuang ◽

Zhenyuan Miao ◽

Lingjian Zhu ◽

Yongqiang Zhang ◽

Zizhao Guo ◽

...

Keyword(s):

Small Molecule ◽

Protein Interaction ◽

Small Molecule Inhibitors ◽

Biological Evaluation ◽

Mdm2 Protein ◽

Protein Protein Interaction ◽

Synthesis And Biological Evaluation

Download Full-text

Novel styryl-indoles as small molecule inhibitors of 25-hydroxyvitamin D-24-hydroxylase (CYP24A1): Synthesis and biological evaluation

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2014.09.035 ◽

2014 ◽

Vol 87 ◽

pp. 39-51 ◽

Author(s):

Salvatore Ferla ◽

Mohamed S. Gomaa ◽

Andrea Brancale ◽

Jinge Zhu ◽

Justin T. Ochalek ◽

...

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors ◽

Biological Evaluation ◽

Hydroxyvitamin D ◽

25 Hydroxyvitamin D ◽

Synthesis And Biological Evaluation

Download Full-text

Design, synthesis and biological evaluation of 2-H pyrazole derivatives containing morpholine moieties as highly potent small molecule inhibitors of APC–Asef interaction

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2019.05.056 ◽

2019 ◽

Vol 177 ◽

pp. 425-447 ◽

Author(s):

Xiao-Qiang Yan ◽

Zhong-Chang Wang ◽

Peng-fei Qi ◽

Guigen Li ◽

Hai-Liang Zhu

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors ◽

Biological Evaluation ◽

Pyrazole Derivatives ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

Download Full-text

Design, Synthesis and Biological Evaluation of Oxindole-Based Chalcones as Small-Molecule Inhibitors of Melanogenic Tyrosinase

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.c17-00301 ◽

2017 ◽

Vol 65 (9) ◽

pp. 833-839 ◽

Author(s):

Sharad Kumar Suthar ◽

Sumit Bansal ◽

Niteen Narkhede ◽

Manju Guleria ◽

Angel Treasa Alex ◽

...

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

Download Full-text

ChemInform Abstract: Synthesis and Biological Evaluation of Thio-benzodiazepines as Novel Small Molecule Inhibitors of the p53-MDM2 Protein-Protein Interaction.

10.1002/chin.201212183 ◽

2012 ◽

Vol 43 (12) ◽

pp. no-no

Author(s):

Chunquan Sheng ◽

et al. et al.

Keyword(s):

Small Molecule ◽

Protein Interaction ◽

Small Molecule Inhibitors ◽

Biological Evaluation ◽

Mdm2 Protein ◽

Protein Protein Interaction ◽

Synthesis And Biological Evaluation

Download Full-text

Design, Synthesis, and Biological Evaluation of Highly Potent Small Molecule–Peptide Conjugates as New HIV-1 Fusion Inhibitors

Journal of Medicinal Chemistry ◽

10.1021/jm3018964 ◽

2013 ◽

Vol 56 (6) ◽

pp. 2527-2539 ◽

Author(s):

Chao Wang ◽

Weiguo Shi ◽

Lifeng Cai ◽

Lu Lu ◽

Qian Wang ◽

...

Keyword(s):

Small Molecule ◽

Biological Evaluation ◽

Peptide Conjugates ◽

Design Synthesis ◽

Fusion Inhibitors ◽

Synthesis And Biological Evaluation ◽

Download Full-text