Antibody microarray immunoassay for screening and differential diagnosis of upper respiratory tract viral pathogens

2020 ◽  
Vol 478 ◽  
pp. 112712 ◽  
Author(s):  
Marina A. Plotnikova ◽  
Sergey A. Klotchenko ◽  
Kirill I. Lebedev ◽  
Alexey A. Lozhkov ◽  
Aleksandr S. Taraskin ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Respiratory Tract ◽  
Upper Respiratory Tract ◽  
Antibody Microarray ◽  
Viral Pathogens ◽  
Microarray Immunoassay ◽  
Upper Respiratory

IDENTIFICATION OF UPPER RESPIRATORY TRACT VIRAL PATHOGENS ISOLATED FROM NASAL SWABS USING OLIGONUCLEOTIDE MICROARRAY

CHEST Journal ◽  
2009 ◽  
Vol 136 (4) ◽  
pp. 65S
Author(s):  
Maria Avgoulea ◽  
Niki Apostolopoulou ◽  
Evangelos Balis ◽  
Nikolaos Spanakis ◽  
Eugenios Metaxas ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Oligonucleotide Microarray ◽  
Upper Respiratory Tract ◽  
Viral Pathogens ◽  
Nasal Swabs ◽  
Upper Respiratory

The management of upper respiratory tract infections

2013 ◽  
Vol 99 (3) ◽  
pp. 97-105
Author(s):  
R Rennie ◽  
B Rennie
Keyword(s):  
Primary Care ◽  
Differential Diagnosis ◽  
Respiratory Tract ◽  
Clinical Picture ◽  
Respiratory Tract Infections ◽  
Upper Respiratory Tract Infections ◽  
Upper Respiratory Tract ◽  
Upper Respiratory ◽  
Tract Infections

AbstractUpper respiratory tract infections (URTIs), generally termed colds, sore throats and coughs, are common presentations in primary care. This article discusses the clinical picture, management, significant differential diagnosis, and specifically, when antibiotics may be required for an URTI.

Viral Upper Respiratory Infection

2020 ◽  
Author(s):  
James Creswell Simpson ◽  
Kristin H. Dwyer
Keyword(s):  
Emergency Department ◽  
Respiratory Tract ◽  
Common Cold ◽  
The United States ◽  
Upper Respiratory Tract ◽  
Viral Pathogens ◽  
Upper Respiratory Infection ◽  
Emergency Department Setting ◽  
Upper Respiratory ◽  
Tract Infections

The upper respiratory tract includes the sinuses, nasal passages, pharynx, and larynx, and is susceptible to a variety of pathogens including many viruses.  Although other pathogens can also cause infections of the upper respiratory tract, we are focusing on viral illnesses for the purposes of this review.  Upper respiratory tract infections (URIs) include sinusitis, nasopharyngitis (common cold), pharyngitis, epiglottitis, and tracheitis.  URI’s are one of the most frequent causes for visits to see a physician in the United States. Despite the fact that many URIs are caused by viral pathogens, more than half of patients in both the clinic and the emergency department setting with a diagnosis of URI received antibiotics. URIs are generally mild, and self-limited illnesses; however, it is important to recognize clinical entities that may be severe and warrant more extensive diagnostic workup and treatment such as epiglottitis and tracheitis. This review covers the pathophysiology, diagnosis, treatment, disposition and outcome for multiple viral URIs seen commonly in the emergency department setting. This review contains 3 figures, 8 tables, and 87 references. Key words: Common cold, epiglottitis, nasopharyngitis, pharyngitis, sinusitis, tracheitis, upper respiratory tract infection  

scholarly journals Subacute Thyroiditis – An Underestimated Diagnosis: Description of a Case Series

2020 ◽  
Vol 47 (1) ◽  
pp. 45-49
Author(s):  
Y. Vlahov ◽  
A-M. Borisova ◽  
M. Nikolova ◽  
A. Kundurdjiev ◽  
R. Ivanova
Keyword(s):  
Differential Diagnosis ◽  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Case Series ◽  
Subacute Thyroiditis ◽  
Upper Respiratory Tract Infections ◽  
Upper Respiratory Tract ◽  
Laboratory Findings ◽  
Upper Respiratory ◽  
Tract Infections

AbstractSubacute thyroiditis is a relatively rare thyroid disease that develops after acute viral upper respiratory tract infection and manifests with neck pain, fever and transient hyperthyroidism. The diagnosis is often delayed due to the non-specific presentation and laboratory findings. It is misdiagnosed with upper respiratory tract infections, cervical lymph-adenitis, even with acute pyelonephritis. The authors present a series of 12 patients with subacute thyroiditis and discuss the main steps in the diagnosis, differential diagnosis and treatment of this disease.

Viral Upper Respiratory Infection

2020 ◽  
Author(s):  
James Creswell Simpson ◽  
Kristin H. Dwyer
Keyword(s):  
Emergency Department ◽  
Respiratory Tract ◽  
Common Cold ◽  
The United States ◽  
Upper Respiratory Tract ◽  
Viral Pathogens ◽  
Upper Respiratory Infection ◽  
Emergency Department Setting ◽  
Upper Respiratory ◽  
Tract Infections

The upper respiratory tract includes the sinuses, nasal passages, pharynx, and larynx, and is susceptible to a variety of pathogens including many viruses.  Although other pathogens can also cause infections of the upper respiratory tract, we are focusing on viral illnesses for the purposes of this review.  Upper respiratory tract infections (URIs) include sinusitis, nasopharyngitis (common cold), pharyngitis, epiglottitis, and tracheitis.  URI’s are one of the most frequent causes for visits to see a physician in the United States. Despite the fact that many URIs are caused by viral pathogens, more than half of patients in both the clinic and the emergency department setting with a diagnosis of URI received antibiotics. URIs are generally mild, and self-limited illnesses; however, it is important to recognize clinical entities that may be severe and warrant more extensive diagnostic workup and treatment such as epiglottitis and tracheitis. This review covers the pathophysiology, diagnosis, treatment, disposition and outcome for multiple viral URIs seen commonly in the emergency department setting. This review contains 3 figures, 8 tables, and 87 references. Key words: Common cold, epiglottitis, nasopharyngitis, pharyngitis, sinusitis, tracheitis, upper respiratory tract infection  

scholarly journals Modelling the co-occurrence of Streptococcus pneumoniae with other bacterial and viral pathogens in the upper respiratory tract

Vaccine ◽  
2007 ◽  
Vol 25 (13) ◽  
pp. 2458-2464 ◽  
Author(s):  
Peter Jacoby ◽  
Kelly Watson ◽  
Jacinta Bowman ◽  
Amanda Taylor ◽  
Thomas V. Riley ◽  
...  
Keyword(s):  
Streptococcus Pneumoniae ◽  
Respiratory Tract ◽  
Upper Respiratory Tract ◽  
Viral Pathogens ◽  
Upper Respiratory

Skin and mucosal lesions in otolaryngological practice

2017 ◽  
Vol 6 (3) ◽  
pp. 30-36
Author(s):  
Piotr Sobolewski ◽  
Laura Ziuzia ◽  
Paweł Dobrzyński ◽  
Irena Walecka
Keyword(s):  
Differential Diagnosis ◽  
Clinical Practice ◽  
Respiratory Tract ◽  
Lichen Planus ◽  
Clinical Presentation ◽  
Main Element ◽  
Upper Respiratory Tract ◽  
Therapeutic Success ◽  
Upper Respiratory ◽  
Mucosal Lesions

Cutaneous and mucosal lesions are seen in many diseases, frequently being the main element of the clinical presentation. It is not uncommon that the patient with mucosal lesions of the upper respiratory tract consults the otolaryngologist first, therefore it is important that those specialists know the mucosal symptoms of dermatological diseases and consider them in the differential diagnosis. In this article diseases with the mucosal lesions of the upper respiratory tract are described, including pemphigus, pemphigoid, lichen planus, and Behçet’s disease. Knowledge of the morphology of these mucosal manifestations is essential in the clinical practice of both dermatologists and otolaryngologists, and the diagnostic and therapeutic success may be achieved only with the cooperation of these specialists.

scholarly journals Patterns of viral pathogens causing upper respiratory tract infections among symptomatic children in Mwanza, Tanzania

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Elizabeth Kwiyolecha ◽  
Britta Groendahl ◽  
Bernard Okamo ◽  
Neema Kayange ◽  
Festo Manyama ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Nasal Congestion ◽  
Full Blood Count ◽  
Upper Respiratory Tract Infections ◽  
Upper Respiratory Tract ◽  
Viral Pathogens ◽  
Common Diagnosis ◽  
Upper Respiratory ◽  
Tract Infections

Abstract Upper-respiratory tract infections (URTI) are the leading causes of childhood morbidities. This study investigated etiologies and patterns of URTI among children in Mwanza, Tanzania. A cross-sectional study involving 339 children was conducted between October-2017 and February-2018. Children with features suggestive of URTI such as nasal congestion, dry cough, painful swallowing and nasal discharge with/without fever were enrolled. Pathogens were detected from nasopharyngeal and ear-swabs by multiplex-PCR and culture respectively. Full blood count and C-reactive protein analysis were also done. The median age was 16 (IQR: 8–34) months. Majority (82.3%) had fever and nasal-congestion (65.5%). Rhinitis (55.9%) was the commonest diagnosis followed by pharyngitis (19.5%). Viruses were isolated in 46% of children, the commonest being Rhinoviruses (23.9%). Nineteen percent of children had more than 2 viruses; Rhinovirus and Enterovirus being the commonest combination. The commonest bacteria isolated from ears were Staphylococcus aureus and Pseudomonas aeruginosa. Children with viral pathogens had significantly right shift of lymphocytes (73%—sensitivity). Majority (257/339) of children were symptoms free on eighth day. Viruses are the commonest cause of URTI with Rhinitis being the common diagnosis. Rapid diagnostic assays for URTI pathogens are urgently needed in low-income countries to reduce unnecessary antibiotic prescriptions which is associated with antibiotic resistance.

Sign in / Sign up

Export Citation Format

Share Document