The antioxidant and non-antioxidant contributions of vitamin E in vitamin E blended ultra-high molecular weight polyethylene for total knee replacement

Author(s):  
Alex Turner ◽  
Yasushi Okubo ◽  
Satoshi Teramura ◽  
Yasuhito Niwa ◽  
Kento Ibaraki ◽  
...  
Author(s):  
Katherine Etter ◽  
Abhishek S Chitnis ◽  
Chantal E Holy ◽  
F Scott Gray ◽  
Fernando J Manalac ◽  
...  

Aim: To examine the time-to-total knee replacement (TKR) surgery among patients with high-concentration nonavian high-molecular-weight hyaluronan injection (HMW-HA) compared with those without HA injections. Materials & methods: Using MarketScan® Commercial claims all patients aged 18–64 who underwent TKR surgery between 2008 and 2017 were identified. Time-to-TKR surgery was compared between patients receiving Orthovisc® (Anika Therapeutics Inc. Bedford MA, USA, referred to as nonavian HMW-HA) injections and patients who did not receive an HA injection. Results: The median time-to-TKR surgery was 893 days in the nonavian HMW-HA cohort and 399 days in the non-HA cohort (p < 0.001), a difference of 494 days (16.2 months). Conclusion: This study demonstrates that the time-to-TKR surgery is 16.2 months longer in patients who received treatment with nonavian HMW-HA injections.


Hyomen Kagaku ◽  
2004 ◽  
Vol 25 (9) ◽  
pp. 568-572 ◽  
Author(s):  
Satoshi TERAMURA ◽  
Naohide TOMITA ◽  
Shunichiro KAWASHIMA ◽  
Kazuhisa FUJITA ◽  
Masahiko AOKI ◽  
...  

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