ULTRA HIGH MOLECULAR-WEIGHT POLYETHYLENE (UHMWPE) IN TOTAL KNEE REPLACEMENT: FABRICATION, STERILISATION AND WEAR

2002 ◽  
Vol 84-B (7) ◽  
pp. 946-949 ◽  
Author(s):  
G. Blunn ◽  
E. M. Brach del Preva ◽  
L. Costa ◽  
J. Fisher ◽  
M. A. R. Freeman
Author(s):  
Katherine Etter ◽  
Abhishek S Chitnis ◽  
Chantal E Holy ◽  
F Scott Gray ◽  
Fernando J Manalac ◽  
...  

Aim: To examine the time-to-total knee replacement (TKR) surgery among patients with high-concentration nonavian high-molecular-weight hyaluronan injection (HMW-HA) compared with those without HA injections. Materials & methods: Using MarketScan® Commercial claims all patients aged 18–64 who underwent TKR surgery between 2008 and 2017 were identified. Time-to-TKR surgery was compared between patients receiving Orthovisc® (Anika Therapeutics Inc. Bedford MA, USA, referred to as nonavian HMW-HA) injections and patients who did not receive an HA injection. Results: The median time-to-TKR surgery was 893 days in the nonavian HMW-HA cohort and 399 days in the non-HA cohort (p < 0.001), a difference of 494 days (16.2 months). Conclusion: This study demonstrates that the time-to-TKR surgery is 16.2 months longer in patients who received treatment with nonavian HMW-HA injections.


2001 ◽  
Author(s):  
Tim McGloughlin

Abstract Wear behaviour of the Ultra High Molecular Weight Polyethylene (UHMWPE) insert in tibial components of total knee implants is believed to be influenced by the contact conditions occurring at the femoro-tibial interface. The wear debris which is generated in the vicinity of the implant is known to evoke undesirable effects and limits the long term survival rates of total knee replacement Mc Gloughlin et al [1].


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