Epidemiology of cerebrovascular disease among Chinese-Canadians: A 20 years retrospective case-mix retrospective study

2017 ◽  
Vol 381 ◽  
pp. 404
Author(s):  
J.Y. Chu ◽  
S. Lam ◽  
D.K. Chu ◽  
J.K. Chu
Author(s):  
JY Chu ◽  
JK Chu ◽  
DK Chu ◽  
S Lam

Introduction: It has been recognized in the past few decades that different ethnic groups living in Canada may have different stroke epidemiology. This presentation is focused on the stroke patterns of Chinese-Canadians living in the Toronto area. Methods: Two retrospective case-controlled studies were carried out between 1990- 2000 to study the stroke characteristics of Chinese-Canadians living in Toronto. Statistical analysis was carried out by the Institute of Clinical Evaluative Sciences. A further retrospective study was also carried out in 2011 to look at the relationship between stroke and diabetes mellitus amongst this population. Results: Chinese-Canadians were found to have 1/6 the prevalence of extracranial vascular stenosis. They have a higher frequency of intracranial vascular disease which may be due to the higher frequency of hypertension and diabetes mellitus. Higher incidence of intracranial hemorrhage was found compared to Caucasian controls which may be due to the lack of awareness and optimal treatment of their hypertension. Details of the results of these three studies will be presented. Conclusions: This is the first long term retrospective study of the stroke patterns and epidemiology for Chinese-Canadians residing in Toronto. Further prospective population-based study will be vital to study the important interactions between genetics and environment in the pathogenesis of different strokes for different folks.


2020 ◽  
pp. 219256822097912
Author(s):  
Kalyan Kumar Varma Kalidindi ◽  
Sulaiman Sath ◽  
Jeevan Kumar Sharma ◽  
Gayatri Vishwakarma ◽  
Harvinder Singh Chhabra

Study Design: Retrospective case-control study. Objective: Neurological deficit is one of the dreaded complications of kyphotic deformity correction procedures. There is inconsistency in the reports of neurological outcomes following such procedures and only a few studies have analyzed the risk factors for neurological deficits. We aimed to analyze the factors associated with neurological deterioration in severe kyphotic deformity correction surgeries. Methods: We performed a retrospective study of 121 consecutive surgically treated severe kyphotic deformity cases (49 males, 56 females) at a single institute (May 1st 2008 to May 31st 2018) and analyzed the risk factors for neurological deterioration. The demographic, surgical and clinical details of the patients were obtained by reviewing the medical records. Results: 105 included patients were divided into 2 groups: Group A (without neurological deficit) with 92 patients (42 males, 50 females) and Group B (with neurological deficit) with 13 patients (7 males, 6 females) (12.4%). Statistically significant difference between the 2 groups was observed in the preoperative sagittal Cobbs angle (p < 0.0001), operative time (p = 0.003) and the presence of myelopathic signs on neurological examination (p = 0.048) and location of the apex of deformity (p = 0.010) but not in other factors. Conclusions: Preoperative Sagittal Cobbs angle, presence of signs of myelopathy, operative time and location of apex in the distal thoracic region were significantly higher in patients with neurological deterioration as compared to those without neurological deterioration during kyphotic deformity correction surgery. Distal thoracic curve was found to have 4 times more risk of neurological deterioration compared to others.


Neurosurgery ◽  
1997 ◽  
Vol 40 (1) ◽  
pp. 53-60
Author(s):  
Toru Iwama ◽  
Nobuo Hashimoto ◽  
Yasushi Takagi ◽  
Tetsuya Tsukahara ◽  
Kohei Hayashida

Neurosurgery ◽  
1997 ◽  
Vol 40 (1) ◽  
pp. 53-60 ◽  
Author(s):  
Toru Iwama ◽  
Nobuo Hashimoto ◽  
Yasushi Takagi ◽  
Tetsuya Tsukahara ◽  
Kohei Hayashida

2019 ◽  
Vol 81 (01) ◽  
pp. 037-042
Author(s):  
Matthew Bartindale ◽  
Ayah Mohamed ◽  
Jason Bell ◽  
Matthew Kircher ◽  
Jacqueline Hill ◽  
...  

Objective The main purpose of this article is to determine the frequency of neurotologic complications after posterior fossa microvascular decompression (MVD) surgery. Design Retrospective case review. Setting Tertiary care referral center. Participants A total of 215 consecutive MVD operations by a single surgeon between March 1996 and May 2016 were reviewed with 192 surgeries on 183 patients meeting inclusion criteria. Main Outcome Measures Neurotologic complications secondary to MVD. Results The 52 males and 131 females had a mean age of 58.52 years (range, 28–92 years). Indications for MVD were trigeminal neuralgia (n = 162), hemifacial spasm (n = 23), glossopharyngeal neuralgia (n = 13), vagal palsy (n = 1), and tinnitus (n = 1). The outcomes examined were postoperative hearing loss, tinnitus, vertigo, and hemifacial paresis. At least one of these complications was present in 17.7% of patients. There were 4.17% with permanent hearing loss, 6.77% with transient hearing loss, 5.21% with tinnitus, 5.73% with vertigo, and 0.52% with hemifacial paresis. There was no significant difference in complication rates based on surgical indication. Conclusions Neurotologic complications are a significant risk when performing MVD. It is important for otolaryngologists as well as neurosurgeons to be aware of such complications. We recommend perioperative audiometry in all patients undergoing MVD and believe there is utility in routine otolaryngologist involvement.


2021 ◽  
pp. 1-7
Author(s):  
Christopher Blair ◽  
Angela Firtko ◽  
Peter Thomas ◽  
Longting Lin ◽  
Megan Miller ◽  
...  

<b><i>Introduction:</i></b> In a multicentre study, we contrasted cerebrovascular disease profiles in Pacific Island (PI)-born patients (Indigenous Polynesian [IP] or Indo-Fijian [IF]) presenting with transient ischaemic attack (TIA), ischaemic stroke (IS) or intracerebral haemorrhage (ICH) with those of Caucasians (CSs). <b><i>Methods:</i></b> Using a retrospective case-control design, we compared PI-born patients with age- and gender-matched CS controls. Consecutive patients were admitted to 3 centres in South Western Sydney (July 2013–June 2020). Demographic and clinical data studied included vascular risk factors, stroke subtypes, and imaging characteristics. <b><i>Results:</i></b> There were 340 CS, 183 (27%) IP, and 157 (23%) IF patients; mean age 65 years; and 302 (44.4%) female. Of these, 587 and patients presented with TIA/IS and 93 (13.6%) had ICH. Both IP and IF patients were significantly more likely to present &#x3e;24 h from symptom onset (odds ratios [ORs] vs. CS 1.87 and 2.23). IP patients more commonly had body mass indexes &#x3e;30 (OR 1.94). Current smoking and excess alcohol intake were higher in CS. Hypertension, diabetes, and chronic kidney disease were significantly higher in both IP and IF groups in comparison to CS. IP patients had higher rates of AF and those with known AF were more commonly undertreated than both IF and CS patients (OR 2.24, <i>p</i> = 0.007). ICH was more common in IP patients (OR 2.32, <i>p</i> = 0.005), while more IF patients had intracranial arterial disease (OR 5.10, <i>p</i> &#x3c; 0.001). <b><i>Discussion/Conclusion:</i></b> Distinct cerebrovascular disease profiles are identifiable in PI-born patients who present with TIA or stroke symptoms in Australia. These may be used in the future to direct targeted approaches to stroke prevention and care in culturally and linguistically diverse populations.


Author(s):  
Gary M. Klein ◽  
T. Peter Seland

ABSTRACT:This retrospective study documents the experience of two large Canadian teaching hospitals with occlusive cerebrovascular disease in young adults. Chart review disclosed 76 patients aged 15-40 years during a recent six year period. An apparent cause, or significant coincident risk factors were found in 51 patients (67%). The most prevalent recognized causes were atherosclerosis, emboli from cardiac sources or intracranial aneurysms, and complicated migraine. Pregnancies or use of oral contraceptives were apparent coincident risk factors.


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