The effects of weight loss on imaging outcomes in overweight or obese people with osteoarthritis in the hip or knee joint: a systematic review of imaging reporting in interventional studies

The aim of this systematic review was to analyze the effect of Nordic Walking (NW) on anthropometric parameters, body composition, cardiovascular parameters, aerobic capacity, blood sample, and glucose tolerance in overweight and obese subjects. The main keywords “Nordic Walking” or “Pole Walking”, associated with either “obese”, “obesity”, “overweight”, or “weight loss” were used on the online database MEDLINE, PubMed, SPORTDiscus and Scopus. Additionally, references of the studies included were screened to identify eligible articles. Applying the inclusion and exclusion criteria, ten manuscripts were considered as eligible for this review. The results of the studies were categorized in several domains with regard to “anthropometric parameters and body composition”, “cardiovascular parameters and aerobic capacity”, and “blood sample and glucose tolerance”. The results showed positive effects on the anthropometric parameters, body composition, cardiovascular parameters, blood sample, and glucose tolerance. The greatest improvements were observed in supervised and high weekly frequency of NW interventions. NW could be considered as an effective modality through which to involve the obese in physical activity. For weight loss, NW should be prescribed 4–5 times per week, at least 60 min per session, preferably combined with diet control.

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Diet-induced weight loss alone or combined with exercise in overweight or obese people with knee osteoarthritis: A systematic review and meta-analysis

Seminars in Arthritis and Rheumatism ◽

10.1016/j.semarthrit.2018.06.005 ◽

2019 ◽

Vol 48 (5) ◽

pp. 765-777 ◽

Cited By ~ 12

Author(s):

Michelle Hall ◽

Birgit Castelein ◽

Ruth Wittoek ◽

Patrick Calders ◽

Ans Van Ginckel

Keyword(s):

Systematic Review ◽

Weight Loss ◽

Knee Osteoarthritis ◽

Meta Analysis ◽

Obese People

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Weight loss is associated with improvements in cognitive function among overweight and obese people: A systematic review and meta-analysis

Neuroscience & Biobehavioral Reviews ◽

10.1016/j.neubiorev.2016.11.017 ◽

2017 ◽

Vol 72 ◽

pp. 87-94 ◽

Cited By ~ 70

Author(s):

Nicola Veronese ◽

Silvia Facchini ◽

Brendon Stubbs ◽

Claudio Luchini ◽

Marco Solmi ◽

...

Keyword(s):

Systematic Review ◽

Weight Loss ◽

Cognitive Function ◽

Meta Analysis ◽

Obese People

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Weight change and change in tibial cartilage volume and symptoms in obese adults

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2013-204488 ◽

2014 ◽

Vol 74 (6) ◽

pp. 1024-1029 ◽

Cited By ~ 40

Author(s):

Andrew J Teichtahl ◽

Anita E Wluka ◽

Stephanie K Tanamas ◽

Yuanyuan Wang ◽

Boyd J Strauss ◽

...

Keyword(s):

Weight Loss ◽

Weight Gain ◽

Knee Joint ◽

Weight Change ◽

Cartilage Volume ◽

Volume Loss ◽

Obese People ◽

Tibial Cartilage ◽

Percentage Weight ◽

Cartilage Volume Loss

IntroductionThere is a paucity of data examining the effects of weight change on knee joint structures and symptoms. This study examined the effect of weight change on change in knee cartilage volume and symptoms in an obese cohort.Methods112 obese subjects (Body Mass Index ≥30 kg/m2) were recruited from various community sources to examine the effect of obesity on musculoskeletal health. Tibial cartilage volume, determined by MRI, and knee symptoms, determined by the Western Ontario and McMaster Osteoarthritis Index (WOMAC) were collected at baseline and an average of 2.3 years later.ResultsPercentage weight change was associated with change in medial tibial cartilage volume (β −1.2 mm3, 95% CI −2.3 to −0.1 mm3, p=0.03) that was consistent throughout the spectrum of weight loss through to mild weight gain. Percentage weight change was not associated with change in the lateral tibial (p=0.93) or patella (p=0.32) cartilage volumes. Percentage weight change was associated with change in all WOMAC subscales (all p≤0.01): pain (β −1.8 mm, 95% CI −3.2 to −0.4 mm), stiffness (β −1.6 mm, 95% CI −2.5 to −0.7 mm) and function (β −6.9 mm, 95% CI −11.6 to −2.1 mm).ConclusionsThe linearity of effect implies that weight loss is associated with reduced medial cartilage volume loss and improved knee symptoms, while weight gain is associated with increased medial cartilage volume loss and worse knee symptoms. These results suggest that in obese people, small amounts of weight change may have the potential for a disease modifying effect on both knee joint structure and symptoms. While weight loss is an important primary management strategy in obese individuals, avoidance of further weight gain should also be a clinical goal.

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