Mental foramen and anterior loop anatomic characteristics: a systematic review and meta-analysis of cross-sectional imaging studies.

Author(s):  
Daniel Almeida Ferreira Barbosa ◽  
Lucca Reis Mesquita ◽  
Marcela Maria Costa Borges ◽  
Diego Santiago de Mendonça ◽  
Francisco Samuel Rodrigues de Carvalho ◽  
...  
BJR|Open ◽  
2021 ◽  
Vol 3 (1) ◽  
pp. 20210005
Author(s):  
Louis Dwyer-Hemmings ◽  
Cassandra Fairhead

Objectives: To synthesise existing evidence for the diagnostic accuracy of chest radiographs to detect lung malignancy in symptomatic patients presenting to primary care. Methods: A systematic review was performed and reported in accordance with the PRISMA framework, using a protocol prospectively registered with the PROSPERO database (CRD42020212450). Nine databases were searched for relevant studies. Data were extracted and chest radiograph sensitivity and specificity calculated where possible. Risk of bias was assessed using a validated tool. Random effects meta-analysis was performed. Results: Ten studies were included. Sensitivity meta-analysis was performed in five studies which were not the high risk of bias, with summary sensitivity of 81% (95% CI: 74–87%). Specificity could be calculated in five studies, with summary specificity of 68% (95% CI: 49–87%). Conclusions: The sensitivity of chest radiographs for detecting lung malignancy in primary care is relatively low. Physicians and policymakers must consider strategies to attenuate the possibility of false reassurance with a negative chest radiograph for this significant pathology. Options include widening access to cross-sectional imaging in primary care; however, any intervention would need to take into account the medical and financial costs of possible over-investigation. Prospective trials with long-term follow-up are required to further evaluate the risks and benefits of this strategy. Advances in knowledge: The chest radiograph has a sensitivity of 81% and specificity of 68% for lung malignancy in a symptomatic primary-care population. A negative chest radiograph does not exclude lung cancer, and physicians should maintain a low threshold to consider specialist referral or cross-sectional imaging.


2019 ◽  
Vol 26 (1) ◽  
pp. 33-42 ◽  
Author(s):  
Shabana F Pasha ◽  
Marco Pennazio ◽  
Emanuele Rondonotti ◽  
Douglas Wolf ◽  
Matthew R Buras ◽  
...  

This systematic review showed lower capsule retention rates in suspected and established Crohn’s disease than older literature. Retention rates were further reduced after patency capsule and cross-sectional imaging. Retention rates were also lower in pediatric compared with adult Crohn’s disease.


2017 ◽  
Vol 16 (4) ◽  
pp. 302-307
Author(s):  
Tom Schlösser ◽  
Rob Brink ◽  
René Castelein

ABSTRACT Despite many years of dedicated research into the etiopathogenesis of adolescent idiopathic scoliosis, there is still no single distinct cause for this puzzling condition. In this overview, we attempt to link knowledge on the complex three-dimensional pathoanatomy of AIS, based on our ongoing research in this field, with etiopathogenic questions. Evidence from multiple recent cross-sectional imaging studies is provided that supports the hypothesis that AIS has an intrinsic biomechanical basis: an imbalance between the biomechanical loading of the upright human spine due to its unique sagittal configuration on the one hand, and the body’s compensating mechanisms on the other. The question that remains in the etiology of AIS, and the focus of our ongoing research, is to determine what causes or induces this imbalance.


2008 ◽  
Vol 15 (10) ◽  
pp. 1217-1226 ◽  
Author(s):  
Kathryn J. Stevens ◽  
Karen L. Griffiths ◽  
Jarrett Rosenberg ◽  
Swaminatha Mahadevan ◽  
Leslie M. Zatz ◽  
...  

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