Effect of ethanolic extract ofPaederia foetidaLinn. leaves on sexual behavior and spermatogenesis in male rats

2012 ◽  
Vol 9 (4) ◽  
pp. 268-276 ◽  
Author(s):  
Devendra K. Soni ◽  
Vikas Sharma ◽  
Nagendra Singh Chauhan ◽  
V.K. Dixit
2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Nagendra Singh Chauhan ◽  
Vikas Sharma ◽  
Mayank Thakur ◽  
Alexandra Christine Helena Frankland Sawaya ◽  
V. K. Dixit

The aim of this study was to investigate the effects of ethanolic extract ofPueraria tuberosa(PT) on sexual behaviour and androgenic activity. Male albino rats were divided into four groups of six animals each: control group 1 (2% acacia solution), PT-treated group 2 (50 mg/Kg), PT-treated group 3 (100 mg/Kg), and PT-treated group 4 (150 mg/Kg). Sexual behavior of male rats in the presence of a female rat was recorded. The treated groups were evaluated for sexual parameters. The extract was characterized using LC-MS. The effect of treatment on anabolic and weight of secondary sexual organs was determined. The histological changes in section of testis and epididymis after treatment were observed. Sperm count in epididymis and fructose content in seminal vesicles were also measured. Levels of hormones like FSH, LH, and T were determined. A dose-dependent increase in sexual behaviors was evidenced in the animals of extract treated groups. Increase in testis weight was recorded in PT. At the highest dose PT also affects the hormones level. The four compounds namely puerarin, daidzein, biochanin-A and formononetin were identified in ethanolic extract using LC-MS. It concluded that PT extract possesses androgenic effect and it significantly increased the sexual behaviour and hormones level.


1982 ◽  
Vol 34 (2) ◽  
pp. 215-220 ◽  
Author(s):  
Kathleen C. Chambers ◽  
Cord B. Sengstake ◽  
Anne M. Walther ◽  
Judith E. Bullis

2003 ◽  
Vol 44 (4) ◽  
pp. 327-337 ◽  
Author(s):  
S Retana-Márquez ◽  
H Bonilla-Jaime ◽  
G Vázquez-Palacios ◽  
R Martínez-García ◽  
J Velázquez-Moctezuma

1999 ◽  
Vol 50 (3) ◽  
pp. 193-199 ◽  
Author(s):  
Reuben W Rhees ◽  
Hamid N Al-Saleh ◽  
Edward W Kinghorn ◽  
Donovan E Fleming ◽  
Edwin D Lephart

1974 ◽  
Vol 5 (2) ◽  
pp. 191-200 ◽  
Author(s):  
Henry Szechtman ◽  
Peter J Lambrou ◽  
Anthony R Caggiula ◽  
Edward S Redgate

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