Therapeutic drug monitoring-enabled long-term use of linezolid for the successful treatment of refractory pyogenic spondylodiscitis without development of thrombocytopenia: A case report

Author(s):  
Takayuki Daisho ◽  
Keisuke Kagami ◽  
Koujiro Yamazaki ◽  
Nobuhisa Ishiguro ◽  
Tsutomu Endo ◽  
...  
2000 ◽  
Vol 152 (1) ◽  
pp. 80-86 ◽  
Author(s):  
Michael Dettling ◽  
Christoph Sachse ◽  
Jürgen Brockmöller ◽  
Jürgen Schley ◽  
Bruno Müller-Oerlinghausen ◽  
...  

2015 ◽  
Vol 30 (suppl_3) ◽  
pp. iii364-iii364
Author(s):  
Jennifer R Joslin ◽  
Paul Blaker ◽  
Oliver Tavabie ◽  
Benjamin White ◽  
Anthony Marinaki ◽  
...  

2018 ◽  
Vol 85 (1) ◽  
pp. 266-269 ◽  
Author(s):  
Pier Giorgio Cojutti ◽  
Maria Merelli ◽  
Lorenzo Allegri ◽  
Giuseppe Damante ◽  
Matteo Bassetti ◽  
...  

2015 ◽  
Vol 33 (Suppl. 1) ◽  
pp. 70-77 ◽  
Author(s):  
Filip Baert

In recent years it has become clear that therapeutic drug monitoring can be an important tool to optimize outcome and costs of anti TNF treatment including the subcutaneous and fully human monoclonal antibodies. There is a clear dose response curve between early serum concentrations of all monoclonal antibodies and response both short term and long term. The wide variations in early serum concentrations are insufficiently explained by classic pharmacokinetic factors. Low early concentrations can lead to anti-drug antibody formation and ensuing loss of response. Therapeutic drug monitoring allows to rationalize the current practice of dose optimization and the use of concomitant immunomodulator treatment. However more prospective studies are needed before strong recommendations can enter treatment guidelines.


2003 ◽  
Vol 18 (5) ◽  
pp. 385-388 ◽  
Author(s):  
Massimo C. Mauri ◽  
Alessio Fiorentini ◽  
Giancarlo Cerveri ◽  
Lucia S. Volonteri ◽  
Francesca Regispani ◽  
...  

2009 ◽  
Vol 877 (23) ◽  
pp. 2301-2307 ◽  
Author(s):  
Nicolas Ansermot ◽  
Serge Rudaz ◽  
Marlyse Brawand-Amey ◽  
Sandrine Fleury-Souverain ◽  
Jean-Luc Veuthey ◽  
...  

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