Analytical methods for the quantification of ibandronate in body fluids and bone

2005 ◽  
Vol 39 (1-2) ◽  
pp. 246-256 ◽  
Author(s):  
Richard Endele ◽  
Heiner Loew ◽  
Frieder Bauss
Keyword(s):  
Analytical Methods ◽  
Body Fluids

Nicotine Workshop

1976 ◽  
Vol 8 (5) ◽  
Author(s):  
xxx
Keyword(s):  
Present State ◽  
Analytical Methods ◽  
Body Fluids ◽  
Advisory Board ◽  
Tobacco Company ◽  
Human Situation ◽  
Tobacco Alkaloids ◽  
Related Compounds ◽  
State Of Art

AbstractA workshop on problems related to the analysis of nicotine and nicotine metabolites in body fluids at levels pertinent to the human situation was held in November 1974 in Stockholm. It was organized by C. Enzell, B. Holmstedt and A. Pilotti at the request of the Medical Advisory Board of the Swedish Tobacco Company. The goal of the workshop was to summarize the present state of art in the area outlined by the organizers and to discuss critically the advantages and limitations of the different analytical methods available today. EIeven experts in the field of metabolism, detection and biosynthesis of nicotine and related compounds were therefore invited to present papers on these topics and to participate in the discussions. AIl speakers invited were able to attend and the papers were arranged in the following groups:Each speaker had one hour and a half at his disposal which included the discussion which, due to the informal atmosphere and the smaII number of participants, was very lively and fruitful. The papers read at this workshop comprise a very valuable coverage of recent research in the fields of metabolism of nicotine and minor tobacco alkaloids, and of the various methods available for detection of these alkaloids. The abstracts are given below, while full papers, now edited by A. Pilotti, can be obtained on request from C. Enzell of the Swedish Tobacco Company

Determination of Fluorine in Biological Materials: A Review

1994 ◽  
Vol 8 (1) ◽  
pp. 80-86 ◽  
Author(s):  
P. Venkateswarlu
Keyword(s):  
Analytical Methods ◽  
Biological Materials ◽  
Body Fluids ◽  
Future Research ◽  
Final Measurement ◽  
Interpretation Of Results

This review on determination of fluorine in biological materials briefly covers (a) a discussion of various forms of fluorine in body fluids and tissues [and also in foods]; (b) methods of their determination, including pretreatment of samples, separation and concentration of F and its final measurement; (c) an evaluation of the analytical methods used and interpretation of results; and (d) some recommendations for future research in fluorine analytical methods applicable to biological materials.

Lactic Dehydrogenase

1964 ◽  
Vol 10 (8) ◽  
pp. 749-758 ◽  
Author(s):  
Myron S Weinberg ◽  
Daniel H Adler
Keyword(s):  
Analytical Methods ◽  
Lactic Dehydrogenase ◽  
Diagnostic Value ◽  
Body Fluids ◽  
Tissue Necrosis ◽  
Ldh Activity ◽  
Mathematical Correlation ◽  
Serial Samples ◽  
Kinetics Of

Abstract Determination of lactic dehydrogenase (LDH) activity has been shown to have diagnostic value in pathologic states involving tissue necrosis and neoplasia. Necrotizing tissues release this enzyme, which catalyzes the reduction of pyruvate to lactate or the reverse, in an active state. As a result of this release, the enzyme appears in body fluids, notably the blood. Increase of this activity over normal indicates necrosis. The present paper compares the results of the Wroblewski and LaDue and the Wacker et al., methods for measuring LDH activity. Results of the two methods were found to be not comparable. No calculation can be found to relate the results of the two analytical methods. Only 18 of 30 samples gave abnormally high results by both methods. Changes between serial samples drawn on the same patient are not always in the same direction when measured by both methods. Lack of mathematical correlation between the kinetics of the pyruvate-to-lactate reaction and the lactate-to-pyruvate reaction is assumed to explain this.

Adenosine, inosine, and hypoxanthine/xanthine measured in tissue and plasma by a luminescence method

1990 ◽  
Vol 36 (1) ◽  
pp. 81-87 ◽  
Author(s):  
C M Jabs ◽  
P Neglen ◽  
B Eklof ◽  
E J Thomas
Keyword(s):  
Human Plasma ◽  
Analytical Methods ◽  
Body Fluids ◽  
Luminescence Method ◽  
Simple Method ◽  
Bilirubin Oxidase ◽  
Analytical Recovery

Abstract This simple method for sequentially quantifying hypoxanthine (HYP), inosine (INO), and adenosine (ADN) concentrations exploits the H2O2 peroxidase-catalyzed chemiluminescence of luminol. Though applied here only to tissue and plasma, this method can be adapted to analyze other body fluids. HYP in human plasma was stable for 30 min in 10 mmol/L EDTA reagent, whereas ADN was slowly converted to INO. Analytical recovery of HYP and INO added to plasma was 102% each; that of ADN was 95%. The within-run mean CVs for determinations of HYP, INO, and ADN at 1 mumol/L were 3.46%, 2.65%, and 3.01%; at 10 mumol/L they were 2.16%, 1.88%, and 1.63%, respectively. Corresponding between-run CVs were 5.34%, 4.09%, and 4.17%; and 3.43%, 2.40%, and 2.88%, respectively. Bilirubin at a concentration greater than 50 mumol/L interferes, but this interference is eliminated by bilirubin oxidase. Results for both tissue and plasma are compared with previously published results based on different analytical methods.

Isolation of Asbestos from Lung Tissue and Sputum

1982 ◽  
Vol 40 ◽  
pp. 330-331
Author(s):  
M. G. Williams ◽  
C. Corn ◽  
R. F. Dodson ◽  
G. A. Hurst
Keyword(s):  
Sodium Hypochlorite ◽  
Lung Tissue ◽  
Body Fluids ◽  
Unknown Etiology ◽  
The Past

During this century, interest in the particulate content of the organs and body fluids of those individuals affected by pneumoconiosis, cancer, or other diseases of unknown etiology developed and concern was further prompted with the increasing realization that various foreign particles were associated with or caused disease. Concurrently particularly in the past two decades, a number of methods were devised for isolating particulates from tissue. These methods were recently reviewed by Vallyathan et al. who concluded sodium hypochlorite digestion was both simple and superior to other digestion procedures.

Stereo modeling of HVEM specimens by serial tilting and computer graphics

1986 ◽  
Vol 44 ◽  
pp. 34-35
Author(s):  
J.R. McIntosh ◽  
D.L. Stemple ◽  
William Bishop ◽  
G.W. Hannaway
Keyword(s):  
Computer Graphics ◽  
Analytical Methods ◽  
Photographic Film ◽  
Complex Structures ◽  
Multiple Objects ◽  
Multiple Images ◽  
3 Dimensional

EM specimens often contain 3-dimensional information that is lost during micrography on a single photographic film. Two images of one specimen at appropriate orientations give a stereo view, but complex structures composed of multiple objects of graded density that superimpose in each projection are often difficult to decipher in stereo. Several analytical methods for 3-D reconstruction from multiple images of a serially tilted specimen are available, but they are all time-consuming and computationally intense.

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