Rapid method for the quantitative determination of efavirenz in human plasma

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2009.03.008 ◽

2009 ◽

Vol 49 (5) ◽

pp. 1308-1312 ◽

Author(s):

Seloi Mogatle ◽

Isadore Kanfer

Keyword(s):

Quantitative Determination ◽

Human Plasma ◽

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Development and validation of an LC–MS/MS method for the quantitative determination of aripiprazole and its main metabolite, OPC-14857, in human plasma

Journal of Chromatography B ◽

10.1016/j.jchromb.2005.06.023 ◽

2005 ◽

Vol 822 (1-2) ◽

pp. 294-299 ◽

Author(s):

Masanori Kubo ◽

Yasuo Mizooku ◽

Yukihiro Hirao ◽

Takahiko Osumi

Keyword(s):

Quantitative Determination ◽

Human Plasma ◽

Main Metabolite ◽

Development And Validation

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Quantitative determination of nystatin in human plasma using LC–MS after inhalative administration in healthy subjects

Journal of Chromatography B ◽

10.1016/j.jchromb.2006.07.015 ◽

2006 ◽

Vol 844 (1) ◽

pp. 84-88 ◽

Author(s):

E SCHEUCH ◽

T GIESMANN ◽

W SIEGMUND

Keyword(s):

Quantitative Determination ◽

Human Plasma ◽

Healthy Subjects

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Quantitative Determination of Progesterone in Human Plasma by Thin-Layer and Gas-Liquid Radiochromatography

Nature ◽

10.1038/203836a0 ◽

1964 ◽

Vol 203 (4947) ◽

pp. 836-839 ◽

Author(s):

WILLIAM P. COLLINS ◽

IAN F. SOMMERVILLE

Keyword(s):

Quantitative Determination ◽

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Method development and validation for quantitative determination of methadone enantiomers in human plasma by liquid chromatography/tandem mass spectrometry1

Journal of Chromatography B ◽

10.1016/j.jchromb.2004.03.059 ◽

2004 ◽

Vol 806 (2) ◽

pp. 191-198 ◽

Author(s):

H LIANG ◽

R FOLTZ ◽

M MENG ◽

P BENNETT

Keyword(s):

Liquid Chromatography ◽

Quantitative Determination ◽

Human Plasma ◽

Method Development ◽

Tandem Mass ◽

Liquid Chromatography Tandem Mass ◽

Method Development And Validation ◽

Development And Validation

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Salting-out homogeneous liquid–liquid extraction approach applied in sample pre-processing for the quantitative determination of entecavir in human plasma by LC–MS

Journal of Chromatography B ◽

10.1016/j.jchromb.2011.12.003 ◽

2012 ◽

Vol 881-882 ◽

pp. 119-125 ◽

Author(s):

Feng-Juan Zhao ◽

Hong Tang ◽

Qing-Hua Zhang ◽

Jin Yang ◽

Andrew K. Davey ◽

...

Keyword(s):

Quantitative Determination ◽

Human Plasma ◽

Liquid Extraction ◽

Salting Out ◽

Homogeneous Liquid ◽

Liquid Liquid Extraction

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Revised method for the quantitative determination of 5-hydroxytryptamine in human plasma by gas chromatography—mass spectrometry—selected ion monitoring

Journal of Chromatography B Biomedical Sciences and Applications ◽

10.1016/s0378-4347(00)84067-0 ◽

1984 ◽

Vol 307 ◽

pp. 1-9 ◽

Author(s):

Shigeo Baba ◽

Masahiro Utoh ◽

Masanobu Horie ◽

Yukio Mori

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

Quantitative Determination ◽

Human Plasma ◽

Gas Chromatography Mass Spectrometry ◽

Selected Ion Monitoring ◽

Chromatography Mass Spectrometry

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Quantitative determination of rhein in human plasma by liquid chromatography–negative electrospray ionization tandem mass/mass spectrometry and the application in a pharmacokinetic study

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2011.09.001 ◽

2012 ◽

Vol 57 ◽

pp. 19-25 ◽

Author(s):

Jun-yi Jiang ◽

Ming-wei Yang ◽

Wei Qian ◽

Hui Lin ◽

Yan Geng ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Quantitative Determination ◽

Electrospray Ionization ◽

Human Plasma ◽

Pharmacokinetic Study ◽

Tandem Mass ◽

Negative Electrospray Ionization

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Quantitative Determination of Prednisone and Prednisolone in Human Plasma Using GLC and Chemical-Ionization Mass Spectrometry

Journal of Pharmaceutical Sciences ◽

10.1002/jps.2600670713 ◽

1978 ◽

Vol 67 (7) ◽

pp. 923-926 ◽

Author(s):

S.B. Matin ◽

B. Amos

Keyword(s):

Mass Spectrometry ◽

Quantitative Determination ◽

Human Plasma ◽

Chemical Ionization ◽

Ionization Mass Spectrometry ◽

Chemical Ionization Mass Spectrometry ◽

Ionization Mass

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Quantitative determination of ɛ-N-carboxymethyl-l-lysine in human plasma by liquid chromatography–tandem mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2013.11.003 ◽

2014 ◽

Vol 90 ◽

pp. 1-6 ◽

Author(s):

Liqing Kuang ◽

Zhiqiang Jing ◽

Jing Wang ◽

Liyuan Ma ◽

Xiaoqiang Liu ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Quantitative Determination ◽

Human Plasma ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Rapid Method for Quantitative Determination of Propoxyphene in Serum by Gas-Liquid Chromatography

Clinical Chemistry ◽

10.1093/clinchem/19.5.492 ◽

1973 ◽

Vol 19 (5) ◽

pp. 492-495 ◽

Author(s):

M A Evenson ◽

Susan Koellner

Keyword(s):

Liquid Chromatography ◽

Quantitative Determination ◽

Rapid Method ◽

Coefficient Of Variation ◽

Therapeutic Dose ◽

Gas Liquid Chromatography ◽

Healthy Controls ◽

Abstract Rapid, accurate, and precise gas-chromatographic methods are reported for measurement of propoxyphene ("Darvon") in serum. A sample of 5 ml of serum is required for quantitation in blood after a therapeutic dose of 130-195 mg of propoxyphene; in cases of overdose of propoxyphene, only 1 ml of serum is required in a "toxic method" variation. Neither serum from healthy controls or from hospitalized patients contains interfering substances. Several commonly used analgesic and sedative drugs, added to a serum pool, also did not interfere. Day-to-day precision of the therapeutic method, as measured by the coefficient of variation (CV), is 7%; the CV for the method as applied to overdose cases is less than 3%. Propoxyphene added to serum could be about 86% accounted for analytically.

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