Mortality in adolescents and young adults with chronic diseases during 16 years: a study in a Latin American tertiary hospital

In Nigeria, there is a paucity of data on knowledge and experiences of adolescents and young adults (AYAs) with HIV and ART, as well as their challenges maintaining optimal adherence. A mixed-method study was carried out between August and September 2018 among AYAs attending Lagos University Teaching Hospital, Nigeria. Data collection was via AYAs' hospital records, standardized questionnaires, and in-depth interviews (IDIs). The 4-day ACTG tool was used to measure adherence. Collected data were analyzed descriptively. Assessment of 34 AYAs comprising 18 (52.9%) males with 28 (82.4%) students revealed an overall knowledge score about ART and its effect of 73.6%. Twenty-five (73.5%) had poor knowledge of the development of resistant strains of HIV due to non-adherence recorded. Optimal adherence (≥95%) was recorded in 20 (58.8%) AYAs. IDI produced 4 themes: (i) reasons for non-adherence, (ii) ensuring optimal adherence, (iii) Social support systems and disclosure, and (iv) stigmatization. Our study provided formative data and revealed areas for intervention to improve knowledge and adherence to ART.

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Antiretroviral therapy outcomes among adolescents and young adults in a Tertiary Hospital in Kenya

African Health Sciences ◽

10.4314/ahs.v21i1.2s ◽

2021 ◽

Vol 21 (1) ◽

pp. 1-7

Author(s):

Patrick Mburugu ◽

Peter Muiruri ◽

Nelly Opiyo ◽

Justus Simba ◽

Jane Adunda ◽

...

Keyword(s):

Young Adults ◽

Viral Load ◽

Cell Count ◽

Tertiary Hospital ◽

Sub Saharan Africa ◽

Adolescents And Young Adults ◽

Virologic Suppression ◽

Late Adolescents ◽

Cd4 Cell Count ◽

Cd4 Cell

Background: Limited data is available on the treatment outcomes of HIV infected adolescents and young adults (AYA) in sub-Saharan Africa. HIV-infected adolescents and young adults (AYA) are at high risk of developing antiretroviral treatment failure. Objective: To determine the clinical, immunological and virologic outcomes of AYA at a tertiary hospital in Kenya. Methodology: A longitudinal study was conducted among AYA age 10-24 years attending Kenyatta National Hospital comprehensive care center. Clinical data was abstracted from electronic medical records for study participants with at least 6 months of follow-up using a structured data abstraction sheet. Results: A total of 250 AYA age 10 to 24 years were included. The median age was 16 years. The median CD4 cell count was 650.6 cells/mm3 (IQR 350.7-884.0). More than half (60.6%) of AYA had a CD4 cell count higher than 500 cells/mm3. Overall, 76.9% of AYA had achieved viral suppression (viral load <1000 copies/ml). There was a significant increase in virologic failure with higher age and late adolescents and young adults were more likely to have a viral load > 1000 copies/ ml p<0.012. Conclusion: The overall virologic suppression in this cohort of AYA was sub-optimal. Both immunological and virologic outcomes were worse among late adolescents (18-19 years) and young adults (20-24 years). Keywords: Adolescents; HIV; Kenya; virologic suppression; young adults.

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Nurses’ perceptions regarding transitional care for adolescents and young adults with childhood‐onset chronic diseases

Japan Journal of Nursing Science ◽

10.1111/jjns.12323 ◽

2020 ◽

Vol 17 (3) ◽

Author(s):

Seigo Suzuki ◽

Sachiko Kita ◽

Mayumi Morisaki ◽

Ryota Kikuchi ◽

Iori Sato ◽

...

Keyword(s):

Young Adults ◽

Chronic Diseases ◽

Transitional Care ◽

Adolescents And Young Adults ◽

Childhood Onset ◽

Nurses Perceptions

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Age of Transition Readiness of Adolescents and Young Adults With Chronic Diseases in Oman

Journal of Pediatric Hematology/Oncology ◽

10.1097/mph.0000000000002389 ◽

2022 ◽

Vol Publish Ahead of Print ◽

Author(s):

Reem Abdwani ◽

Muna al Saadoon ◽

Sanjay Jaju ◽

Mohamed Elshinawy ◽

Asmaa Almaimani ◽

...

Keyword(s):

Young Adults ◽

Chronic Diseases ◽

Adolescents And Young Adults ◽

Transition Readiness

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Antiretroviral therapy outcomes among adolescents and young adults in a Tertiary Hospital in Kenya

African Health Sciences ◽

10.4314/ahs.v21i.2s ◽

2021 ◽

Vol 21 ◽

pp. 1-7

Author(s):

Patrick Mburugu ◽

Peter Muiruri ◽

Nelly Opiyo ◽

Justus Simba ◽

Jane Adunda ◽

...

Keyword(s):

Young Adults ◽

Viral Load ◽

Cell Count ◽

Tertiary Hospital ◽

Sub Saharan Africa ◽

Adolescents And Young Adults ◽

Virologic Suppression ◽

Late Adolescents ◽

Cd4 Cell Count ◽

Cd4 Cell

Background: Limited data is available on the treatment outcomes of HIV infected adolescents and young adults (AYA) in sub-Saharan Africa. HIV-infected adolescents and young adults (AYA) are at high risk of developing antiretroviral treatment failure. Objective: To determine the clinical, immunological and virologic outcomes of AYA at a tertiary hospital in Kenya. Methodology: A longitudinal study was conducted among AYA age 10-24 years attending Kenyatta National Hospital comprehensive care center. Clinical data was abstracted from electronic medical records for study participants with at least 6 months of follow-up using a structured data abstraction sheet. Results: A total of 250 AYA age 10 to 24 years were included. The median age was 16 years. The median CD4 cell count was 650.6 cells/mm3 (IQR 350.7-884.0). More than half (60.6%) of AYA had a CD4 cell count higher than 500 cells/mm3. Overall, 76.9% of AYA had achieved viral suppression (viral load <1000 copies/ml). There was a significant increase in virologic failure with higher age and late adolescents and young adults were more likely to have a viral load > 1000 copies/ ml p<0.012. Conclusion: The overall virologic suppression in this cohort of AYA was sub-optimal. Both immunological and virologic outcomes were worse among late adolescents (18-19 years) and young adults (20-24 years). Keywords: Adolescents; HIV; Kenya; virologic suppression; young adults.

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Clinical presentation of autoinflammatory diseases in children, adolescents and young adults: a Latin American multicenter study

10.47660/cbr.2021.1778 ◽

2021 ◽

Author(s):

Daniela Piotto ◽

Pedro Henrique L. Carneiro ◽

Katia Kozu ◽

Nádia Emi Aikawa ◽

María Martha Katsicas ◽

...

Keyword(s):

Young Adults ◽

Latin American ◽

Multicenter Study ◽

Clinical Presentation ◽

Adolescents And Young Adults ◽

Autoinflammatory Diseases

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Cigarette Smoking and Alcohol Use among Adolescents and Young Adults with Asthma

Nursing Research and Practice ◽

10.1155/2011/503201 ◽

2011 ◽

Vol 2011 ◽

pp. 1-7 ◽

Cited By ~ 4

Author(s):

Elizabeth Burgess Dowdell ◽

Michael A. Posner ◽

M. Katherine Hutchinson

Keyword(s):

Young Adults ◽

Alcohol Use ◽

Cigarette Smoking ◽

Health Risk ◽

Chronic Diseases ◽

Risk Behaviors ◽

Secondary Analysis ◽

Health Risk Behaviors ◽

Adolescents And Young Adults ◽

Behavior Change Interventions

Asthma is one of the most common, serious chronic diseases in pediatric and young adult populations. Health-risk behaviors, including cigarette smoking and alcohol use, may exacerbate chronic diseases and complicate their management. The aim of this study was to longitudinally analyze rates of cigarette smoking and alcohol use in adolescents and young adults who have asthma and those who do not have asthma. A secondary analysis of data from the National Longitudinal Study of Adolescent Health was undertaken. Individuals with asthma were found to exhibit increasing rates of cigarette smoking and alcohol use as they aged. When an adolescent with a chronic health issue begins health-risk-taking behaviors, behavior change interventions must be planned. Pediatric nurses, practitioners, and clinicians are uniquely positioned to assess for health-risk behaviors in youth with asthma and to intervene with plans of care that are tailored for the needs of this vulnerable population.

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