Rare missense coding variants in oxytocin receptor ( OXTR ) in schizophrenia cases are associated with early trauma exposure, cognition and emotional processing

2018 ◽  
Vol 97 ◽  
pp. 58-64 ◽  
Author(s):  
Andre B. Veras ◽  
Mara Getz ◽  
Robert C. Froemke ◽  
Antonio Egidio Nardi ◽  
Gilberto Sousa Alves ◽  
...  
2012 ◽  
Author(s):  
Damion Grasso ◽  
Julian Ford ◽  
Margaret Briggs-Gowan

2017 ◽  
Vol 35 (21-22) ◽  
pp. 4709-4731 ◽  
Author(s):  
Melissa J. London ◽  
Mary C. Mercer ◽  
Michelle M. Lilly

Recent research has demonstrated that first responders may report posttraumatic growth (PTG), positive psychological changes that arise in the aftermath of a trauma. Less is known regarding the perception of PTG among 9-1-1 telecommunicators, a group of first responders exposed to a high degree of lifetime trauma, including duty-related trauma as well as early and non-duty-related trauma. Moreover, the impact of childhood trauma on the processes involved in the perception of growth is less clear. While some distress is needed to facilitate processes that lead to the perception of PTG, it has been suggested that positive associations between PTG and pathology reflect avoidant coping or represent an illusory component of PTG. Structural equation models were used to examine early trauma exposure, coping, and pathology in predicting PTG among 9-1-1 telecommunicators ( N = 788). In separate models using active and avoidant forms of coping, childhood trauma exposure had an indirect effect on PTG through coping. In a model considering both forms of coping, childhood trauma had an indirect effect on PTG through psychopathology, but not through coping. The results show that early trauma exposure leads to the perception of growth through pathways indicative of both adaptive and maladaptive coping processes.


Psychology ◽  
2019 ◽  
Author(s):  
Patricia A. Frazier ◽  
Emily Mischel Abramowski ◽  
Viann Nguyen-Feng ◽  
Addie Merians ◽  
McKenzie Kaubrys

Trauma research often uses the definition of trauma in the diagnostic criteria for posttraumatic stress disorder (PTSD), which in general terms involves experiencing a life-threatening event. Using this definition, the majority of individuals have experienced at least one traumatic event in their lifetime, with some demographic groups being at greater risk (e.g., sexual minorities). Nonetheless, many other kinds of events can be distressing besides those that meet the definition of trauma in the criteria for PTSD, including adverse childhood experiences, racial microaggressions, morally injurious events, and historical trauma. Much research on the effects of trauma also focuses on PTSD. This research shows that although most individuals experience at least one traumatic event in their lifetime, few (5 percent–10 percent) trauma-exposed individuals develop PTSD. Thus, research also has examined resilient outcomes following trauma exposure, defined as stable functioning following adversity. In the developmental literature, resilience refers to adequate long-term adaptation across life domains despite chronic childhood adversity whereas, in the adult trauma literature, resilience has been defined as having minimal symptoms posttrauma. Research in both child and adult samples suggests that resilience is the modal response to trauma and adversity. However, the conclusion that resilience is the modal response to adult trauma has recently come under criticism on methodological grounds. Finally, posttraumatic growth (PTG) refers to reports of better functioning in various life domains posttrauma. Although such reports are common, this area of research also has been criticized on methodological grounds based on the finding that self-reported growth is tenuously related to actual pre- to posttrauma change. Because of the diversity of responses to trauma exposure, an important question concerns which factors predict better or poorer adjustment in response to traumatic events. These risk and protective factors include pretrauma, trauma-related, and posttraumatic characteristics. For example, female gender is a risk factor for PTSD partly because women are at greater risk of sexual violence, which is the trauma type that carries the highest PTSD risk. With regard to posttrauma factors, lack of social support is a particularly important risk factor. Progress has been made in terms of developing effective treatments for preventing and treating PTSD. In the immediate posttrauma phase, psychological debriefing (without emotional processing) is recommended. In the acute phase, Cognitive Behavioral Therapy (CBT) is recommended for the prevention of PTSD. CBT and exposure therapies are recommended for treating PTSD. Less is known about the promotion of resilience or PTG.


2016 ◽  
Vol 26 (4) ◽  
pp. 270-292
Author(s):  
Signe Hjelen Stige ◽  
Margrethe Seeger Halvorsen

This article presents a narrative case study of a client with a history of multiple traumas and severe symptomatology, coupled with an ongoing recovery process. A hermeneutical–phenomenological approach was used to analyze two interviews with the participant over a period of 1 year, following a trauma treatment program. Her husband’s suicide in between the two interviews allowed for an exploration of the possible effects of new trauma exposure on the process of recovery. Analysis of the data revealed how the participant’s early trauma experiences had resulted in escalating symptomatology. Through her relationship with her husband, she gradually became ready to engage in therapy in a way that allowed her to benefit from it. Her husband’s suicide forced her to reconsider her own part in her recovery, resulting in a strengthened feeling of inner security and self-efficacy parallel to what is seen in posttraumatic growth. The results contribute our understanding of individual processes of change and recovery, including processes of growth following cumulative trauma. Plausible mechanisms for growth in the present case was the ability to recognize and tolerate feelings, making sense of one’s own reactions, as well as a sense of control and trust in available resources.


2014 ◽  
Vol 40 (5) ◽  
pp. 1250-1258 ◽  
Author(s):  
Hilary A Marusak ◽  
Kayla R Martin ◽  
Amit Etkin ◽  
Moriah E Thomason

2016 ◽  
Vol 71 ◽  
pp. 308-314 ◽  
Author(s):  
Christina Campbell ◽  
Yvonne Roberts ◽  
Frank Synder ◽  
Jordan Papp ◽  
Michael Strambler ◽  
...  

Author(s):  
Debra Kaysen ◽  
Keren Lehavot ◽  
Emily R. Dworkin

This chapter describes the prevalence of trauma exposure and related mental health disorders among sexual minority women (SMW). It reviews theoretical models that explain the ways in which trauma exposure among SMW may lead to mental health concerns, including minority stress, insidious trauma, and psychological mediation theoretical frameworks, as well as how other theoretical frameworks such as emotional processing theory and social cognitive theory may be applied to SMW. The chapter then briefly reviews the literature on assessment and on leading treatment approaches for trauma-related disorders in the general population, and it discusses how these may be tailored for SMW. Throughout the chapter, illustrative case examples of how to apply these principles with SMW are presented. Finally, it concludes with future directions and emerging trends in the field.


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