Regulation of decidualization, interleukin-11 and interleukin-15 by homeobox A 10 in endometrial stromal cells

2010 ◽  
Vol 85 (2) ◽  
pp. 130-139 ◽  
Author(s):  
Geeta Godbole ◽  
Deepak Modi
Keyword(s):  
Stromal Cells ◽  
Endometrial Stromal Cells ◽  
Interleukin 15 ◽  
Interleukin 11

scholarly journals The Production of Interleukin-11 and Decidualization Are Compromised in Endometrial Stromal Cells Derived from Patients with Infertility

2005 ◽  
Vol 90 (3) ◽  
pp. 1607-1612 ◽  
Author(s):  
Natalia Karpovich ◽  
Petra Klemmt ◽  
Jung Hye Hwang ◽  
J. Enda McVeigh ◽  
John K. Heath ◽  
...  
Keyword(s):  
Stromal Cells ◽  
Endometrial Stromal Cells ◽  
Interleukin 11

Interleukin-11 enhances cell survival of decidualized normal human endometrial stromal cells

2001 ◽  
Vol 15 (4) ◽  
pp. 272-278 ◽  
Author(s):  
T. Tanaka ◽  
T. Sakamoto ◽  
M. Miyama ◽  
S. Ogita ◽  
N. Umesaki
Keyword(s):  
Cell Survival ◽  
Stromal Cells ◽  
Endometrial Stromal Cells ◽  
Normal Human ◽  
Interleukin 11

Interleukin 1 beta is induced by interleukin 11 during decidualization of human endometrial stromal cells, but is not released in a bioactive form

2007 ◽  
Vol 73 (1) ◽  
pp. 28-38 ◽  
Author(s):  
Christine A. White ◽  
Evdokia Dimitriadis ◽  
Andrew M. Sharkey ◽  
Chelsea J. Stoikos ◽  
Lois A. Salamonsen
Keyword(s):  
Stromal Cells ◽  
Interleukin 1 ◽  
Interleukin 1 Beta ◽  
Endometrial Stromal Cells ◽  
Interleukin 11

scholarly journals Progesterone Enhances Interleukin-15 Production in Human Endometrial Stromal Cells in Vitro1

2000 ◽  
Vol 85 (12) ◽  
pp. 4765-4770 ◽  
Author(s):  
Hidetaka Okada ◽  
Tatsuya Nakajima ◽  
Mayumi Sanezumi ◽  
Akiko Ikuta ◽  
Katsuhiko Yasuda ◽  
...  
Keyword(s):  
Mrna Expression ◽  
Stromal Cells ◽  
Hormonal Control ◽  
Human Endometrium ◽  
Enzyme Linked Immunosorbent Assay ◽  
Mrna Levels ◽  
Dependent Manner ◽  
Endometrial Stromal Cells ◽  
Potent Inducer ◽  
Interleukin 15

Interleukin-15 (IL-15) is a novel cytokine that stimulates lymphocyte proliferation and migration via a trimeric receptor sharing the β andγ signal-transducing chains with the IL-2 receptor. It is suggested that IL-15 is involved in regulating the proliferation and differentiation of uterine natural killer cells. In the human endometrium, we have recently reported that IL-15 messenger ribonucleic acid (mRNA) levels significantly increased during the secretory phase compared with those during the proliferative phase. In this study we investigated whether the female sex steroids progesterone (P) and estradiol (E2) regulate IL-15 messenger RNA (mRNA) and the secretion in human endometrial stromal cells (ESC) in vitro. Northern blot analyses revealed a significant increase in IL-15 mRNA levels in ESC treated with P alone or E2 plus P compared with vehicle. Furthermore, P is a potent inducer of IL-15 mRNA expression in ESC in a dose-dependent manner. On the other hand, E2 alone did not increase IL-15 mRNA expression. By enzyme-linked immunosorbent assay, IL-15 protein secretion was stimulated by P and further enhanced by combined treatment with E2 and P, whereas E2 alone was ineffective. It is suggested that IL-15 is deeply involved in the hormonal control of the human endometrium by P and E2.

Interleukin-11 enhances cell survival of decidualized normal human endometrial stromal cells

2001 ◽  
Vol 15 (4) ◽  
pp. 272-278 ◽  
Author(s):  
T. Tanaka ◽  
T. Sakamoto ◽  
M. Miyama ◽  
S. Ogita ◽  
N. Umesaki
Keyword(s):  
Cell Survival ◽  
Stromal Cells ◽  
Endometrial Stromal Cells ◽  
Normal Human ◽  
Interleukin 11
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