Changes in the content of steroid receptor coactivator-1 and silencing mediator for retinoid and thyroid hormone receptors in the rat brain during the estrous cycle

2005 ◽  
Vol 94 (1-3) ◽  
pp. 267-272 ◽  
Author(s):  
Ignacio Camacho-Arroyo ◽  
Teresa Neri-Gómez ◽  
Aliesha González-Arenas ◽  
Christian Guerra-Araiza
Keyword(s):  
Thyroid Hormone ◽  
Rat Brain ◽  
Estrous Cycle ◽  
Hormone Receptors ◽  
Steroid Receptor ◽  
Thyroid Hormone Receptors ◽  
Steroid Receptor Coactivator

scholarly journals Polychlorinated biphenyls (PCBs) exert thyroid hormone-like effects in the fetal rat brain but do not bind to thyroid hormone receptors.

2004 ◽  
Vol 112 (5) ◽  
pp. 516-523 ◽  
Author(s):  
Kelly J Gauger ◽  
Yoshihisa Kato ◽  
Koichi Haraguchi ◽  
Hans-Joachim Lehmler ◽  
Larry W Robertson ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Polychlorinated Biphenyls ◽  
Rat Brain ◽  
Hormone Receptors ◽  
Thyroid Hormone Receptors ◽  
Fetal Rat ◽  
Fetal Rat Brain

Immunocytochemical Localization of Thyroid Hormone Receptors in the Adult Rat Brain

Thyroid ◽  
1991 ◽  
Vol 1 (2) ◽  
pp. 173-184 ◽  
Author(s):  
J. PUYMIRAT ◽  
M. MIEHE ◽  
R. MARCHAND ◽  
L. SARLIEVE ◽  
J.H. DUSSAULT
Keyword(s):  
Thyroid Hormone ◽  
Rat Brain ◽  
Hormone Receptors ◽  
Thyroid Hormone Receptors ◽  
Immunocytochemical Localization ◽  
Adult Rat ◽  
Adult Rat Brain

scholarly journals Isoform-Specific Transcriptional Regulation by Thyroid Hormone Receptors: Hormone-Independent Activation Operates through a Steroid Receptor Mode of Coactivator Interaction

2001 ◽  
Vol 15 (7) ◽  
pp. 1170-1185 ◽  
Author(s):  
Zhihong Yang ◽  
Martin L. Privalsky
Keyword(s):  
Thyroid Hormone ◽  
Transcriptional Activation ◽  
Hormone Receptors ◽  
Steroid Hormone ◽  
Expression Patterns ◽  
Steroid Receptor ◽  
Steroid Hormone Receptors ◽  
Thyroid Hormone Receptors ◽  
Interaction Domain ◽  
Specific Expression

Abstract Thyroid hormone receptors (T3Rs) are hormone-regulated transcription factors that play important roles in vertebrate homeostasis, differentiation, and development. T3Rs are synthesized as multiple isoforms that display tissue-specific expression patterns and distinct transcriptional properties. Most T3R isoforms associate with coactivator proteins and mediate transcriptional activation only in the presence of thyroid hormone. The pituitary-specific T3Rβ-2 isoform departs from this general rule and is able to interact with p160 coactivators, and to mediate transcriptional activation in both the absence and presence of hormone. We report here that this hormone-independent activation is mediated by contacts between the unique N terminus of T3Rβ-2 and an internal interaction domain in the SRC-1 (steroid receptor coactivator-1) and GRIP-1 (glucocorticoid receptor interacting protein 1) coactivators. These hormone-independent contacts between T3Rβ-2 and the p160 coactivators are distinct in sequence and function from the LXXLL motifs that mediate hormone-dependent transcriptional activation and resemble instead a mode of coactivator recruitment previously observed only for the steroid hormone receptors and only in the presence of steroid hormone. Our results suggest that the transcriptional properties of the different T3R isoforms represent a combinatorial mixture of repression, antirepression, and hormone-independent and hormone-dependent activation functions that operate in conjunction to determine the ultimate transcriptional outcome.

Lithium administration affects gene expression of thyroid hormone receptors in rat brain

Life Sciences ◽  
1999 ◽  
Vol 64 (20) ◽  
pp. 1793-1802 ◽  
Author(s):  
Chang-Gyu Hahn ◽  
Aaron C. Pawlyk ◽  
Peter C. Whybrow ◽  
Lazlo Gyulai ◽  
Shanaz M. Tejani-Butt
Keyword(s):  
Gene Expression ◽  
Thyroid Hormone ◽  
Rat Brain ◽  
Hormone Receptors ◽  
Thyroid Hormone Receptors

scholarly journals Thyroid Hormone Receptors in the Developing Rat Brain

1978 ◽  
Vol 18 (3) ◽  
pp. 545-552 ◽  
Author(s):  
SINGARAM NAIDOO ◽  
THEONY VALCANA ◽  
PAOLA S. TIMIRAS
Keyword(s):  
Thyroid Hormone ◽  
Rat Brain ◽  
Hormone Receptors ◽  
Thyroid Hormone Receptors ◽  
Developing Rat

Thyroid Hormone Receptors in Neuronal and Glial Nuclei from Mature Rat Brain

Endocrinology ◽  
1986 ◽  
Vol 118 (5) ◽  
pp. 1770-1776 ◽  
Author(s):  
TOSHIHIKO YOKOTA ◽  
HIROTOSHI NAKAMURA ◽  
TAKASHI AKAMIZU ◽  
TORU MORI ◽  
HIROO IMURA
Keyword(s):  
Thyroid Hormone ◽  
Rat Brain ◽  
Hormone Receptors ◽  
Thyroid Hormone Receptors

Effects of gestational hypoxia on mRNA levels of Glut3 and Glut4 transporters, hypoxia inducible factor-1 and thyroid hormone receptors in developing rat brain

2000 ◽  
Vol 856 (1-2) ◽  
pp. 119-128 ◽  
Author(s):  
Christophe Royer ◽  
Joël Lachuer ◽  
Gabriel Crouzoulon ◽  
Jean-Christophe Roux ◽  
Julie Peyronnet ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Rat Brain ◽  
Hormone Receptors ◽  
Hypoxia Inducible Factor ◽  
Thyroid Hormone Receptors ◽  
Mrna Levels ◽  
Hypoxia Inducible Factor 1 ◽  
Developing Rat
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