scholarly journals Early Postoperative Oral Intake Accelerates Upper Gastrointestinal Anastomotic Healing in the Rat Model

2011 ◽  
Vol 169 (2) ◽  
pp. 202-208 ◽  
Author(s):  
Sosuke Tadano ◽  
Hideo Terashima ◽  
Junya Fukuzawa ◽  
Ryota Matsuo ◽  
Osamu Ikeda ◽  
...  
Keyword(s):  
Rat Model ◽  
Oral Intake ◽  
Anastomotic Healing ◽  
Upper Gastrointestinal

Early Postoperative Oral Feeding Accelerates Upper Gastrointestinal Anastomotic Healing in the Rat Model

2007 ◽  
Vol 31 (6) ◽  
pp. 1236-1241 ◽  
Author(s):  
Junya Fukuzawa ◽  
Hideo Terashima ◽  
Nobuhiro Ohkohchi
Keyword(s):  
Rat Model ◽  
Oral Feeding ◽  
Anastomotic Healing ◽  
Upper Gastrointestinal

scholarly journals Upper Gastrointestinal obstruction as an Unusual Presentation of Thoracoabdominal Huge Aortic Aneurysm; a Case Report

2021 ◽  
Author(s):  
Fatemeh Jahanshahi ◽  
Sam Zeraatian Davani
Keyword(s):  
Abdominal Pain ◽  
Case Report ◽  
Aortic Aneurysm ◽  
Oral Intake ◽  
Thoracoabdominal Aortic Aneurysm ◽  
Mural Thrombus ◽  
Gastrointestinal Obstruction ◽  
Acute Rupture ◽  
Aneurysm Repair ◽  
Upper Gastrointestinal

We reported a case with complaint of abdominal pain, nausea, vomiting, and oral intake intolerance due to a giant thoracoabdominal aortic aneurysm with contained leak and acute rupture within the circumferential mural thrombus which presented with upper gastrointestinal obstruction manifestation. The rupture led to the patient undergoing emergency aneurysm repair.

scholarly journals Erratum: Correction of Affiliation

2020 ◽  
Vol 64 (1) ◽  
Author(s):  
Roberto Ghiselli ◽  
Guendalina Lucarini ◽  
Monica Ortenzi ◽  
Eleonora Salvolini ◽  
Stefania Saccomanno ◽  
...  
Keyword(s):  
Animal Models ◽  
Drug Administration ◽  
Rat Model ◽  
Anastomotic Healing ◽  
Inflammatory Drug ◽  
Research Department ◽  
Anti Inflammatory ◽  
Technological Area ◽  
Italian National Institute

This corrects the article "Anastomotic healing in a rat model of peritonitis after non-steroidal anti-inflammatory drug administration " in volume 64(1):3085 In the published article “Anastomotic healing in a rat model of peritonitis after non-steroidal anti-inflammatory drug administration” Eur J Histochem 2020;64(1):3085, https://doi.org/10.4081/ejh.2020.3085,” one affiliation was published incorrectly. The authors apologize for any inconvenience that it may have caused. Roberto Ghiselli,1 Guendalina Lucarini,2 Monica Ortenzi,1 Eleonora Salvolini,3 Stefania Saccomanno,2 Fiorenza Orlando,4 Mauro Provinciali,4 Fabio Casciani,1 Mario Guerrieri1 1Clinic of Surgery, Marche Polytechnic University, Ancona2Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona3Department of Odontostomatologic and Specialized Clinical Sciences, Marche Polytechnic University, Ancona4Experimental Animal Models for Aging Units, Research Department, Italian National Institute on Aging (INRCA) IRCCS, Ancona, Italy The affiliation should be corrected as follows: 4Experimental Animal Models for Aging Units, Scientific Technological Area, IRCCS INRCA, Ancona, Italy

scholarly journals The effect of pasireotide on intestinal anastomotic healing with and without whole-body irradiation in a rat model

2018 ◽  
Vol 34 (2) ◽  
pp. 337-345
Author(s):  
Gabriel J. Seifert ◽  
Gunnar Leithold ◽  
Birte Kulemann ◽  
Philipp A. Holzner ◽  
Torben Glatz ◽  
...  
Keyword(s):  
Rat Model ◽  
Anastomotic Healing ◽  
Whole Body

scholarly journals EARLY ORAL FEEDING POST-UPPER GASTROINTESTINAL TRACT RESECTION AND PRIMARY ANASTOMOSIS IN ONCOLOGY

2018 ◽  
Vol 31 (1) ◽  
Author(s):  
Lilian Pinheiro LOPES ◽  
Taysa Machado MENEZES ◽  
Diogo Oliveira TOLEDO ◽  
Antônio Talvane Torres DE-OLIVEIRA ◽  
Adhemar LONGATTO-FILHO ◽  
...  
Keyword(s):  
Enteral Nutrition ◽  
Total Gastrectomy ◽  
Primary Anastomosis ◽  
Gastrointestinal Surgery ◽  
Oral Intake ◽  
Wound Dehiscence ◽  
Oral Feeding ◽  
Oral Nutrition ◽  
Early Oral Feeding ◽  
Upper Gastrointestinal

ABSTRACT Background: The practice of starving patients in the immediate period after upper gastrointestinal surgery is widespread. Early oral intake has been shown to be feasible and may result in faster recovery and decrease length of hospital. Aim: To evaluate the feasibility and safety of oral nutrition on postoperative early feeding after upper gastrointestinal surgeries. Methods: Observational cohort design study with convenience retrospective data in both genders, over 18 years, undergoing to total gastrectomy and/or elective esophagectomy. They have received oral or enteral nutrition in less than 48 h after surgery, and among those who started with enteral nutrition, the oral feeding up to seven days. Results: The study was performed in 161 patients, 24 (14.9%) submitted to esophagectomy, 132 (82%) to total gastrectomy and five (3.1%) to esophagogastrectomy. Was observed good dietary acceptance and low percentage (29%) of gastrointestinal intolerances, more pronounced among those with enteral diet. Most of the patients did not present postoperative complications, 11 (6.8%) were reopened, five (3.1%) had fistulas, three (1.9%) wound dehiscence, three (1.9%) fistula more wound dehiscence and six (3.7%) other non-infectious complications. Conclusion: Early oral diet is safe and viable for patients undergoing upper gastrointestinal surgery.

scholarly journals Suicidal acid ingestion leading to gastric outlet obstruction treated by early definitive surgery—case report

2021 ◽  
Vol 2021 (2) ◽  
Author(s):  
Mutlaq Almalki ◽  
Waed Yaseen ◽  
Shatha Althobaiti
Keyword(s):  
Small Bowel ◽  
Outlet Obstruction ◽  
Oral Intake ◽  
Acute Injury ◽  
Gastric Injury ◽  
Gastric Lumen ◽  
Injury Treatment ◽  
Definitive Surgery ◽  
Physiological Outcomes ◽  
Upper Gastrointestinal

Abstract Chemical ingestions can cause acute injury to the oesophagus, stomach, pylorus, duodenum and sometimes other organs after ingestion of corrosives, but it may be as late as 1 year after ingestion. A 30-year-old male patient presented to the emergency department with sudden epigastric abdominal pain after flash material ingestion. Computed tomography of abdomen showed signs of small bowel obstruction associated with segmental small bowel ischaemic changes. Postoperatively, patient developed an intolerance to oral intake with upper gastrointestinal scope showing sever stricture at the distal gastric lumen and pylorus. The patient was taken to the operation where gastrojejunostomy and brown procedure was done. Corrosive gastric injury treatment depends on the degree of gastric involvement, related oesophageal strictures and the patient’s general health. Early surgery offers very satisfactory and physiological results, whereas avoiding gastric resection or bypass provides very satisfactory and physiological outcomes.

scholarly journals Pill-induced esophagitis caused by ingesting excessive caffeine tablets

2019 ◽  
Vol 13 (3) ◽  
pp. 334-339 ◽  
Author(s):  
Jun Miyata ◽  
Yoshiyuki Ito ◽  
Shigeji Ito
Keyword(s):  
Conservative Treatment ◽  
Dietary Supplement ◽  
Gastrointestinal Endoscopy ◽  
Oral Intake ◽  
Endoscopic Surveillance ◽  
Upper Gastrointestinal Endoscopy ◽  
Lower Esophagus ◽  
Retrosternal Pain ◽  
Upper Gastrointestinal

Abstract A 19-year-old woman with suicidal thoughts consumed 24 anhydrous caffeine tablets and was admitted to our hospital. After being discharged from the hospital, her oral intake remained impaired because of retrosternal pain and she was readmitted. An upper gastrointestinal endoscopy revealed diffuse ulcers throughout the mid-to-lower esophagus; the patient was diagnosed with caffeine-induced esophagitis. She recovered soon after conservative treatment. A follow-up endoscopy performed 1 month after the patient was discharged showed that the ulcers had healed. This case highlights the risk of esophageal injuries after ingesting excessive caffeine tablets, which were sold as dietary supplement without a prescription. Our experience indicates that endoscopic surveillance is advisable to prevent severe complications if a patient presents with esophageal symptoms suggestive of chemical esophagitis.

scholarly journals Anastomotic healing in a rat model of peritonitis after non-steroidal anti-inflammatory drug administration

2020 ◽  
Vol 64 (1) ◽  
Author(s):  
Roberto Ghiselli ◽  
Guendalina Lucarini ◽  
Monica Ortenzi ◽  
Eleonora Salvolini ◽  
Stefania Saccomanno ◽  
...  
Keyword(s):  
Rat Model ◽  
Healing Process ◽  
Gastrointestinal Surgery ◽  
Morphological Features ◽  
Male Rats ◽  
Anastomotic Healing ◽  
Bursting Pressure ◽  
Mmp9 Expression ◽  
Significant Difference ◽  
Anti Inflammatory

The tissue inflammatory response can influence the outcome of anastomotic healing. Anastomotic leakage represents a dreadful complication after gastrointestinal surgery, in particular sepsis and intra-abdominal infections impair the restorative process of colic anastomoses. It has been debated whether the administration of non-steroidal anti-inflammatory drugs (NSAIDs) is a risk factor for dehiscence, since many patients receive NSAIDs in the early postoperative period. Our aim was, for the first time, to analyze the morpho-functional effects of postoperative administration of two commonly used NSAIDs, Diclofenac and Ketorolac, on the healing process of colo-colic anastomoses constructed under condition of fecal peritonitis in a rat model. Sixty adult male rats underwent two surgical procedures: peritonitis induction and colo-colic anastomosis, and were divided into three groups: 20 rats received saline; 20 rats 4 mg/kg Diclofenac and 20 rats 5 mg/kg Ketorolac. We assessed anastomosis strength, morphological features of tissue wound healing, immunohistochemical metalloproteinase 9 (MMP9) expression and collagen deposition and content by Sirius red staining and hydroxyproline level. We found no significant difference in bursting pressure, collagen content and organization and morphological features between the groups, except a significantly reduced presence of inflammatory cells and MMP9 expression in the groups treated with NSAIDs. Our findings showed that Diclofenac and Ketorolac administration did not affect post-surgical healing and did not increase the leakage risk of colo-colic anastomoses during peritonitis.

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