Zinc status at baseline is not related to acute changes in serum zinc concentration following bouts of running or cycling

2018 ◽  
Vol 50 ◽  
pp. 105-110
Author(s):  
Anna Chu ◽  
Peter Petocz ◽  
Samir Samman
Keyword(s):  
Zinc Concentration ◽  
Serum Zinc ◽  
Zinc Status ◽  
Serum Zinc Concentration ◽  
Acute Changes

Serum zinc status in thalassemic adolescents attending Yangon Children Hospital, Myanmar

2020 ◽  
Author(s):  
Win-Yu Aung ◽  
Thae-Nu Htwe ◽  
Myat Thandar ◽  
Ohn Mar
Keyword(s):  
Zinc Deficiency ◽  
Day Care ◽  
Zinc Concentration ◽  
Zinc Supplementation ◽  
Care Center ◽  
Serum Zinc ◽  
Delayed Puberty ◽  
Zinc Status ◽  
Day Care Center ◽  
Serum Zinc Concentration

Background: Thalassemia constitutes a major public health problem causing a significant burden on children and their families. Zinc deficiency plays an important role in many thalassemia-related complications like growth retardation, hypogonadism and delayed puberty which are frequently noted in adolescent age. Although zinc is supplemented to thalassemic patients visiting Day Care Center, Yangon Children Hospital (YCH), Myanmar, a report concerning serum zinc level of these patients is still lacking. This study, therefore, aimed to assess serum zinc status in thalassemic adolescents attending Day Care Center, YCH. Materials and Methods: This hospital-based cross-sectional study was conducted on 99 thalassemic adolescents. Mean age of diagnosis was 5.1±2.1 years. Non-fasting serum zinc concentration was determined by atomic absorption spectrophotometry. According to National Health and Nutrition Examination Survey data, zinc deficiency was defined as serum zinc concentration < 66 μg/dL (female) and < 70 μg/dL (male). Results: Serum zinc concentration (μg/dL) was 57.35 (47.30-80.14) (median, interquartile range) with maximum, 195.05 and minimum, 28.83. Zinc deficiency was observed in 69.7% (69 out of 99; 35 males and 34 females) of the patients. The associations of zinc deficiency with gender, phenotype and the use of chelator were non-significant (P>0.05). Conclusion: In spite of zinc supplementation, nearly 70% of the thalassemic adolescents showed zinc deficiency. Zinc deficiency in these adolescents might not be related to gender, phenotypes or the use of chelator. Poor compliance to take zinc supplementation and/or irregular blood transfusion could partly be attributable to zinc deficiency in these adolescents. Providing health education on the importance of regular intake of adequate zinc is advisable and periodic evaluation of zinc levels is recommended for thalassemic adolescents.

scholarly journals Assessment of Zinc Status Among Pregnant Women Attending a Tertiary Level Hospital of Sunsari District, Nepal

2020 ◽  
Vol 17 (4) ◽  
pp. 468-473
Author(s):  
Man Kumar Tamang ◽  
Uday Narayan Yadav ◽  
Anish Acharya ◽  
Madhab Lamsal
Keyword(s):  
Pregnant Women ◽  
Zinc Deficiency ◽  
Zinc Concentration ◽  
Serum Zinc ◽  
P Value ◽  
Tertiary Level ◽  
Zinc Status ◽  
Chi Square ◽  
Serum Zinc Concentration ◽  
Level Hospital

Background: Zinc deficiency is one of the major public health problems especially in developing countries, with an estimation of over 80% of pregnant women to be zinc deficient worldwide. Maternal zinc deficiency elevates the risk of foetal growth restriction. This study aimed to assess zinc deficiency and to examine the factors associated with zinc status among pregnant women attending a tertiary level hospital in Sunsari district, province no. one, Nepal.Methods: Pregnant women were selected by using time frame consecutive sampling at B. P. Koirala Institute of Health Sciences, Dharan from September to November 2018. Data on nutritional, socio-demographic and reproductive profiles were collected using a semi-structured questionnaire. Blood was collected from each pregnant woman to estimate serum zinc concentration by atomic absorption spectrophotometry. Association between serum zinc concentration and predictor variables were assessed using chi-square test.Results: A total of 156 women participated in the study. The prevalence of zinc deficiency among the pregnant women was 22.6%. Our data did not show association of any of the socio-demographic, nutritional and reproductive variables with serum zinc status (p-value>0.05) in chi-square. Conclusions: Zinc deficiency was found to be prevalent in our targeted population. However, community based studies need to be conducted for exploring more precise relationship between zinc status and other variables.Keywords: Nepal; nutritional factors; pregnant women; zinc status.

scholarly journals A Zinpyr-1-based Fluorimetric Microassay for Free Zinc in Human Serum

2019 ◽  
Vol 20 (16) ◽  
pp. 4006 ◽  
Author(s):  
Alker ◽  
Schwerdtle ◽  
Schomburg ◽  
Haase
Keyword(s):  
Human Serum ◽  
Zinc Concentration ◽  
Serum Zinc ◽  
Sample Volume ◽  
Total Serum ◽  
Zinc Status ◽  
Serum Samples ◽  
Human Serum Samples ◽  
Serum Zinc Concentration ◽  
Free Zinc

Zinc is an essential trace element, making it crucial to have a reliable biomarker for evaluating an individual’s zinc status. The total serum zinc concentration, which is presently the most commonly used biomarker, is not ideal for this purpose, but a superior alternative is still missing. The free zinc concentration, which describes the fraction of zinc that is only loosely bound and easily exchangeable, has been proposed for this purpose, as it reflects the highly bioavailable part of serum zinc. This report presents a fluorescence-based method for determining the free zinc concentration in human serum samples, using the fluorescent probe Zinpyr-1. The assay has been applied on 154 commercially obtained human serum samples. Measured free zinc concentrations ranged from 0.09 to 0.42 nM with a mean of 0.22 ± 0.05 nM. It did not correlate with age or the total serum concentrations of zinc, manganese, iron or selenium. A negative correlation between the concentration of free zinc and total copper has been seen for sera from females. In addition, the free zinc concentration in sera from females (0.21 ± 0.05 nM) was significantly lower than in males (0.23 ± 0.06 nM). The assay uses a sample volume of less than 10 µL, is rapid and cost-effective and allows us to address questions regarding factors influencing the free serum zinc concentration, its connection with the body’s zinc status, and its suitability as a future biomarker for an individual’s zinc status.

Use of Serum Zinc Concentration as an Indicator of Population Zinc Status

2007 ◽  
Vol 28 (3_suppl3) ◽  
pp. S403-S429 ◽  
Author(s):  
Sonja Y. Hess ◽  
Janet M. Peerson ◽  
Janet C. King ◽  
Kenneth H. Brown
Keyword(s):  
Zinc Deficiency ◽  
Zinc Concentration ◽  
Zinc Supplementation ◽  
Serum Zinc ◽  
Interindividual Variation ◽  
Zinc Status ◽  
Dietary Zinc ◽  
Serum Zinc Concentration ◽  
Zinc Concentrations ◽  
Intervention Trials

Assessing the prevalence and severity of zinc deficiency in populations is critical to determine the need for and appropriate targeting of zinc intervention programs and to assess their effectiveness for improving the health and well-being of high-risk populations. However, there is very little information on the zinc status of populations worldwide due to the lack of consensus on appropriate biochemical indicators of zinc status. The objective of this review was to evaluate the use of serum zinc concentration as an indicator of population zinc status. We have reviewed the response of serum zinc concentration to dietary zinc restriction and zinc supplementation. In addition, we completed pooled analyses of nine zinc intervention trials in young children to assess the relations between serum zinc concentration of individuals before treatment and their responses to zinc supplementation. Also, in updated combined analyses of previously published data, we investigated the relation between the mean initial serum zinc concentration of a study population and their mean growth responses to zinc supplementation in randomized intervention trials among children. The results from depletion/repletion studies indicate that serum zinc concentrations respond appreciably to severe dietary zinc restriction, although there is considerable interindividual variation in these responses. There is also clear evidence that both individual and population mean serum zinc concentrations increase consistently during zinc supplementation, regardless of the initial level of serum zinc concentration. By contrast, an individual's serum zinc concentration does not reliably predict that person's response to zinc supplementation. Serum zinc concentration can be considered a useful biomarker of a population's risk of zinc deficiency and response to zinc interventions, although it may not be a reliable indicator of individual zinc status.

A positive association between maternal serum zinc concentration and birth weight

1990 ◽  
Vol 51 (4) ◽  
pp. 678-684 ◽  
Author(s):  
Y H Neggers ◽  
G R Cutter ◽  
R T Acton ◽  
J O Alvarez ◽  
J L Bonner ◽  
...  
Keyword(s):  
Birth Weight ◽  
Zinc Concentration ◽  
Serum Zinc ◽  
Positive Association ◽  
Maternal Serum ◽  
Serum Zinc Concentration

Reduced Serum Zinc Concentration During Pregnancy

1983 ◽  
Vol 62 (3) ◽  
pp. 313-318 ◽  
Author(s):  
C. A. SWANSON ◽  
J. C. KING
Keyword(s):  
Zinc Concentration ◽  
Serum Zinc ◽  
Serum Zinc Concentration

Serum Zinc Level in Pre-eclamptic Pregnancies: Association with Clinical Complication

1970 ◽  
Vol 39 (1) ◽  
pp. 7-10
Author(s):  
Touhida Ahsan ◽  
Razia Sultana Begum ◽  
Sheikh Naznul Islam
Keyword(s):  
Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Zinc Concentration ◽  
Serum Zinc ◽  
Zinc Level ◽  
Contributory Factor ◽  
Serum Zinc Concentration ◽  
Correlative Analysis ◽  
Blood Pressures ◽  
In Pregnancy

Pre-eclampsia is one of the fatal complications in pregnancy. Zinc plays an important role in the course and eventual outcome of human pregnancy, and is essential for normal embryogenesis and fetal growth. Zinc deficiency in pregnancy is thought to be associated with pre-eclampsia. The aim of this study was, therefore, to investigate the scum zinc level in pre-eclampsia and to examine its association (if any) with pre-eclampsia. A case control study was done among 45 pre-eclamptic and 35 normotensive pregnants at their third trimester. Serum zinc concentration was determined by Atomic Absorption Flame Spectrophotometric method. Correlative analysis was made to find any correlation, of serum zinc with blood Pressure. Results showed identical Maternal and gestational age, and different gravida distribution for the patients and controls, and significantly (P<0.005) higher blood pressures (systolic and diastolic) for pre-eclampsia. Serum zinc concentration were estimated 0.65±0.09mg/L in pre-eclamsia and 0.60±0.08mg/L in pregnant controls, difference of which was insignificant (p=0.284). Correlative analysis wowed that there was a linear correlation between serum level and diastolic blood pressure, but it was found to be insignificant (r=0.158, p=0.330). It was suggested that changes in zinc status may not be an etiological or contributory factor in pre-eclamsia. Key words: Serum zinc; pre-eclampsia; diastolic blood pressure DOI: 10.3329/bmj.v39i1.6226 Bangladesh Medical Journal 2010; 39(1): 7-10

Relationship Between Serum Zinc Concentration with Post-partum Depression among Women in Coastal Area of Indonesia

2019 ◽  
Vol 18 (8) ◽  
pp. 747-752 ◽  
Author(s):  
R. Indriasari ◽  
Y. Kurniati ◽  
A. Syam ◽  
S. Syamsuddin ◽  
M.A Mansur ◽  
...  
Keyword(s):  
Coastal Area ◽  
Zinc Concentration ◽  
Post Partum ◽  
Serum Zinc ◽  
Post Partum Depression ◽  
Serum Zinc Concentration
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