IMPROVING THE ACCURACY OF CHLORIDE MEASUREMENTS THROUGH PARTICIPATION IN REGULAR EXTERNAL QUALITY ASSESSMENT PROGRAMME

Author(s):  
Wesley Zongrong Yu ◽  
Qinde Liu ◽  
Ho Wah Leung ◽  
Benny M.K. Tong ◽  
Gina Chew ◽  
...  
2014 ◽  
Vol 19 (8) ◽  
Author(s):  
D Luijt ◽  
C Di Lorenzo ◽  
A M van Loon ◽  
M Unemo

We describe the results of the Quality Control for Molecular Diagnostics 2013 Neisseria gonorrhoeae external quality assessment programme that included an N. gonorrhoeae strain harbouring an N. meningitidis porA gene which causes false-negative results in molecular diagnostic assays targeting the gonococcal porA pseudogene. Enhanced awareness of the international transmission of such gonococcal strains is needed to avoid false-negative results in both in-house and commercial molecular diagnostic assays used in laboratories worldwide, but particularly in Europe.


Author(s):  
Debrah I. Boeras ◽  
Rosanna W. Peeling ◽  
Philip Onyebujoh ◽  
Ali A. Yahaya ◽  
Hieronyma N. Gumede-Moeletsi ◽  
...  

External Quality Assessment (EQA) surveys performed by the World Health Organization Regional Office for Africa (WHO AFRO) revealed the need for the strengthening of publichealth microbiology laboratories, particularly for testing of epidemic-prone diseases in theAfrican Region. These surveys revealed common issues such as supply chain managementskilled personnel, logistical support and overall lack of quality standards. For sustainableimprovements to health systems as well as global health security, deficiencies identified needto be actively corrected through robust quality assurance programmes and implementation oflaboratory quality management systems.Given all the pathogens of public health importance, an external quality assessment programmewith a focus on vaccine-preventable diseases and emerging and re-emerging dangerouspathogens is important, and should not be stand-alone, but integrated within laboratorynetworks as seen in polio, measles, yellow fever and rubella.In 2015, WHO AFRO collaborated with the US Centers for Disease Control and Preventionthe London School of Hygiene & Tropical Medicine and partners in a series of consultationswith countries and national and regional EQA providers for the development of qualityassurance models to support HIV point-of-care testing and monitoring. These consultationsrevealed similar challenges as seen in the WHO AFRO surveys. WHO AFRO brought forthits experience in implementing quality standards for health programmes, and also openeddiscussions on how lessons learned through such established programmes can be utilised tosupporting and strengthening the introduction of early infant diagnosis of HIV and viralload point-of-care testing.An optimised external quality assessment programme will impact the ability of countries tomeet core capacities, providing improved quality management systems, improving theconfidence of diagnostic network services in Africa, and including capacities to detect eventsof international public health importance.


Haemophilia ◽  
2018 ◽  
Vol 25 (1) ◽  
pp. 162-169 ◽  
Author(s):  
Iris van Moort ◽  
Piet Meijer ◽  
Debby Priem-Visser ◽  
Adriaan J. van Gammeren ◽  
Nathalie C. V. Péquériaux ◽  
...  

Author(s):  
Geir Thue ◽  
Sverre Sandberg

AbstractAnalytical performance specifications can be based on three different models: the effect of analytical performance on clinical outcome, based on components of biological variation of the measurand or based on state-of-the-art. Models 1 and 3 may to some degree be combined by using case histories presented to a large number of clinicians. The Norwegian Quality Improvement of Primary Care Laboratories (Noklus) has integrated vignettes in its external quality assessment programme since 1991, focusing on typical clinical situations in primary care. Haemoglobin, erythrocyte sedimentation rate (ESR), HbA


Author(s):  
Nalia Ismael ◽  
Orvalho Augusto ◽  
Adolfo Vubil ◽  
Sofia O. Viegas ◽  
Fernanda Miambo ◽  
...  

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