Establishment of a proficiency panel for an external quality assessment programme for the detection of bacterial contamination in platelet concentrates using rapid and cultural detection methods

Vox Sanguinis ◽  
2016 ◽  
Vol 110 (4) ◽  
pp. 336-343 ◽  
Author(s):  
T. Vollmer ◽  
M. Schmidt ◽  
K. Hourfar ◽  
V. Schottstedt ◽  
L. Pichl ◽  
...  
Keyword(s):  
Quality Assessment ◽  
Bacterial Contamination ◽  
External Quality Assessment ◽  
Detection Methods ◽  
Platelet Concentrates ◽  
External Quality ◽  
Proficiency Panel ◽  
Assessment Programme

scholarly journals Bench Test for the Detection of Bacterial Contamination in Platelet Concentrates Using Rapid and Cultural Detection Methods with a Standardized Proficiency Panel

2015 ◽  
Vol 42 (4) ◽  
pp. 220-225 ◽  
Author(s):  
Tanja Vollmer ◽  
Cornelius Knabbe ◽  
Wolf-Jochen Geilenkeuser ◽  
Michael Schmidt ◽  
Jens Dreier
Keyword(s):  
Bacterial Contamination ◽  
Detection Methods ◽  
Bench Test ◽  
Platelet Concentrates ◽  
Proficiency Panel

scholarly journals Most but not all laboratories can detect the recently emerged Neisseria gonorrhoeae porA mutants – results from the QCMD 2013 N. gonorrhoeae external quality assessment programme

2014 ◽  
Vol 19 (8) ◽  
Author(s):  
D Luijt ◽  
C Di Lorenzo ◽  
A M van Loon ◽  
M Unemo
Keyword(s):  
Neisseria Gonorrhoeae ◽  
Quality Assessment ◽  
External Quality Assessment ◽  
False Negative ◽  
Molecular Diagnostic ◽  
External Quality ◽  
Diagnostic Assays ◽  
Assessment Programme ◽  
Negative Results ◽  
False Negative Results

We describe the results of the Quality Control for Molecular Diagnostics 2013 Neisseria gonorrhoeae external quality assessment programme that included an N. gonorrhoeae strain harbouring an N. meningitidis porA gene which causes false-negative results in molecular diagnostic assays targeting the gonococcal porA pseudogene. Enhanced awareness of the international transmission of such gonococcal strains is needed to avoid false-negative results in both in-house and commercial molecular diagnostic assays used in laboratories worldwide, but particularly in Europe.

Precision and accuracy of commercial assays for vancomycin therapeutic drug monitoring: evaluation based on external quality assessment scheme

2020 ◽  
Author(s):  
Chao-Yang Chen ◽  
Meng-Ya Li ◽  
Ling-Yun Ma ◽  
Xing-Yu Zhai ◽  
Dao-Huang Luo ◽  
...  
Keyword(s):  
Serum Concentration ◽  
Quality Assessment ◽  
Bacterial Infections ◽  
External Quality Assessment ◽  
Detection Methods ◽  
Therapeutic Drug ◽  
External Quality ◽  
External Quality Assessment Scheme ◽  
Percentage Difference ◽  
Precision And Accuracy

Abstract Background Vancomycin remains a mainstay of the treatment of Gram-positive bacterial infections. It is crucial to accurately determine vancomycin serum concentration for adequate dose adjustment. Objectives To evaluate the precision and accuracy of commercial assay techniques for vancomycin concentration and to assess the comparability of vancomycin detection methods in Chinese laboratories. Methods Human serum samples spiked with known concentrations of vancomycin were provided to laboratories participating in the external quality assessment scheme (EQAS). Assay methods included chemiluminescence, enzyme immunoassay (EIA) and so on. The dispersion of the measurements was analysed and the robust coefficient of variation (rCV), relative percentage difference (RPD) and satisfactory rate for method groups were calculated. Moreover, performance of the Chinese laboratories was assessed. Results A total of 657 results from 75 laboratories were collected, including 84 samples from 10 Chinese laboratories. The median rCV, median RPD and satisfactory rates classified by methods ranged from 1.85% to 15.87%, −14.75% to 13.34% and 94.59% to 100.00%, respectively. Significant differences were seen in precision, between kinetic interaction of microparticles in solution (KIMS) and other methods, and in accuracy, between enzyme-multiplied immunoassay technique (EMIT), fluorescence polarization immunoassay (FPIA) and other techniques. Vancomycin detection in China mainly depended on the chemiluminescence and EMIT methods, which tended to result in lower measurements. Conclusions Although almost all assays in this study achieved an acceptable performance for vancomycin serum concentration monitoring, obvious inconsistencies between methods were still observed. Chinese laboratories were more likely to underestimate vancomycin concentrations. Thus, recognizing inconsistencies between methods and regular participation in vancomycin EQAS are essential.

scholarly journals The WHO AFRO external quality assessment programme (EQAP): Linking laboratory networks through EQA programmes

2016 ◽  
Vol 5 (2) ◽  
Author(s):  
Debrah I. Boeras ◽  
Rosanna W. Peeling ◽  
Philip Onyebujoh ◽  
Ali A. Yahaya ◽  
Hieronyma N. Gumede-Moeletsi ◽  
...  
Keyword(s):  
Public Health ◽  
Quality Management ◽  
Quality Assessment ◽  
External Quality Assessment ◽  
Point Of Care ◽  
Quality Standards ◽  
World Health ◽  
Public Health Importance ◽  
External Quality ◽  
Assessment Programme

External Quality Assessment (EQA) surveys performed by the World Health Organization Regional Office for Africa (WHO AFRO) revealed the need for the strengthening of publichealth microbiology laboratories, particularly for testing of epidemic-prone diseases in theAfrican Region. These surveys revealed common issues such as supply chain managementskilled personnel, logistical support and overall lack of quality standards. For sustainableimprovements to health systems as well as global health security, deficiencies identified needto be actively corrected through robust quality assurance programmes and implementation oflaboratory quality management systems.Given all the pathogens of public health importance, an external quality assessment programmewith a focus on vaccine-preventable diseases and emerging and re-emerging dangerouspathogens is important, and should not be stand-alone, but integrated within laboratorynetworks as seen in polio, measles, yellow fever and rubella.In 2015, WHO AFRO collaborated with the US Centers for Disease Control and Preventionthe London School of Hygiene & Tropical Medicine and partners in a series of consultationswith countries and national and regional EQA providers for the development of qualityassurance models to support HIV point-of-care testing and monitoring. These consultationsrevealed similar challenges as seen in the WHO AFRO surveys. WHO AFRO brought forthits experience in implementing quality standards for health programmes, and also openeddiscussions on how lessons learned through such established programmes can be utilised tosupporting and strengthening the introduction of early infant diagnosis of HIV and viralload point-of-care testing.An optimised external quality assessment programme will impact the ability of countries tomeet core capacities, providing improved quality management systems, improving theconfidence of diagnostic network services in Africa, and including capacities to detect eventsof international public health importance.

Point of Care INR testing devices: performance of the Roche CoaguChek XS and XS Plus in the UK NEQAS BC external quality assessment programme for healthcare professionals: four years’ experience

2012 ◽  
Vol 65 (12) ◽  
pp. 1119-1123 ◽  
Author(s):  
Dianne Patricia Kitchen ◽  
Steven Kitchen ◽  
Ian Jennings ◽  
Timothy AL Woods ◽  
David A Fitzmaurice ◽  
...  
Keyword(s):  
Quality Assessment ◽  
Healthcare Professionals ◽  
External Quality Assessment ◽  
Point Of Care ◽  
External Quality ◽  
Assessment Programme ◽  
Coaguchek Xs ◽  
The Uk

IMPROVING THE ACCURACY OF CHLORIDE MEASUREMENTS THROUGH PARTICIPATION IN REGULAR EXTERNAL QUALITY ASSESSMENT PROGRAMME

2021 ◽  
pp. 126825
Author(s):  
Wesley Zongrong Yu ◽  
Qinde Liu ◽  
Ho Wah Leung ◽  
Benny M.K. Tong ◽  
Gina Chew ◽  
...  
Keyword(s):  
Quality Assessment ◽  
External Quality Assessment ◽  
External Quality ◽  
Assessment Programme

scholarly journals Analytical variation in factor VIII one-stage and chromogenic assays: Experiences from the ECAT external quality assessment programme

Haemophilia ◽  
2018 ◽  
Vol 25 (1) ◽  
pp. 162-169 ◽  
Author(s):  
Iris van Moort ◽  
Piet Meijer ◽  
Debby Priem-Visser ◽  
Adriaan J. van Gammeren ◽  
Nathalie C. V. Péquériaux ◽  
...  
Keyword(s):  
Factor Viii ◽  
Quality Assessment ◽  
External Quality Assessment ◽  
External Quality ◽  
Assessment Programme ◽  
One Stage ◽  
Analytical Variation

Analytical performance specifications based on how clinicians use laboratory tests. Experiences from a post-analytical external quality assessment programme

2015 ◽  
Vol 53 (6) ◽  
Author(s):  
Geir Thue ◽  
Sverre Sandberg
Keyword(s):  
Primary Care ◽  
Quality Assessment ◽  
External Quality Assessment ◽  
State Of The Art ◽  
Analytical Performance ◽  
Case Histories ◽  
External Quality ◽  
Assessment Programme ◽  
Erythrocyte Sedimentation ◽  
Performance Specifications

AbstractAnalytical performance specifications can be based on three different models: the effect of analytical performance on clinical outcome, based on components of biological variation of the measurand or based on state-of-the-art. Models 1 and 3 may to some degree be combined by using case histories presented to a large number of clinicians. The Norwegian Quality Improvement of Primary Care Laboratories (Noklus) has integrated vignettes in its external quality assessment programme since 1991, focusing on typical clinical situations in primary care. Haemoglobin, erythrocyte sedimentation rate (ESR), HbA

scholarly journals External Quality Assessment Programme for Early Infant Diagnosis of HIV-1, Mozambique, 2011–2014

2018 ◽  
Vol 7 (1) ◽  
Author(s):  
Nalia Ismael ◽  
Orvalho Augusto ◽  
Adolfo Vubil ◽  
Sofia O. Viegas ◽  
Fernanda Miambo ◽  
...  
Keyword(s):  
Quality Assessment ◽  
External Quality Assessment ◽  
Early Infant Diagnosis ◽  
External Quality ◽  
Assessment Programme ◽  
Early Infant ◽  
Hiv 1
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