Epidemiological survey of the status of iodine nutrition and thyroid diseases in Guangxi, China

Author(s):  
Li-Heng Meng ◽  
Cui-Hong Chen ◽  
Ying Liu ◽  
Xing-Huan Liang ◽  
Jia Zhou ◽  
...  
2018 ◽  
Author(s):  
Zhongyan Shan ◽  
Weiping Teng ◽  
Yongze Li ◽  
Guang Ning ◽  
Yiming Mu ◽  
...  

2019 ◽  
Vol 15 (2) ◽  
pp. 38-41
Author(s):  
Michael B. Zimmermann

The status of iodine nutrition is a key factor in determining the prevalence of thyroid disorders in adults. The study under discussion provides data on the change in the incidence of nosological subtypes of overt thyrotoxicosis and hypothyroidism in adults during an increase in iodine intake after the introduction of mandatory salt iodization in Denmark. The authors carefully studied the case histories of all new patients with thyrotoxicosis and hypothyroidism registered in 2014–2016 in an open cohort of the population of Northern Jutland (n = 309,434), in which a moderate iodine deficiency has historically been observed and compared with incidence rates in 1997–1998 years before introduction of mandatory salt iodization began 2001. Over this period of time, iodine intake almost doubled. At the same time, the incidence rate of confirmed overt thyrotoxicosis significantly decreased: from the initial rate of 97.5 cases per 100,000 people per year in 1997–2000 to 48.8 cases per 100,000 people per year in 2014–2016. This result was due to a significant decrease in the incidence of multinodular toxic goiter, toxic adenoma and Graves’ disease in all age groups in both women and men. Moreover, the overall incidence of primary overt hypothyroidism has not changed.


2020 ◽  
Vol 35 ◽  
pp. 153331752092532
Author(s):  
Chengping Hu ◽  
Ling Wang ◽  
Yi Guo ◽  
Zhicheng Cao ◽  
Ying Lu ◽  
...  

Objective: To evaluate the risk factors for progress of mild cognitive impairment to dementia. Methods: This study was based on the epidemiological survey in 2011 (No. PKJ2010-Y26) and contained 441 MCI individuals. Cognitive function was measured by the Mini-Mental Status Examination, clinical dementia rating, and montreal cognitive assessment. The association between demographic characteristics and MCI outcomes were evaluated using single-and multifactor ordered logistic regression analysis models. Results: Of the 441 MCI, 77 progressed to dementia (MCIp: 17.5%, 95% CI: 14.4%-21.6%), 356 remained stable (MCIs: 80.7%, 95% CI: 77.0%-88.4%), and 8 reverted to normal cognition (MCIr: 1.8%, 95% CI: 0.6%-3.0%) at follow-up in 2017. Univariate ordinal regression analysis showed that diabetes ( P = .052), marriage ( P = .028), worker ( P = .069), and manager ( P = .075) may be the risk factor for the status of MCI. Multiple ordinal regression results showed that diabetes ( P = .049) and marriage ( P = .04) significantly affected the cognitive function changes in the MCI patients. Conclusion: Nondiabetics and being married may prevent the progression from MCI to dementia.


Author(s):  
Fereidoun Azizi

: “Cure” has been referred to maintaining a healthy situation before the occurrence of the illness. With emerging non-communicable chronic diseases, many treatment approaches and management of these disorders have been found to control the disease, despite the fact that the status of the human body does not return to like it was before the illness. Patients become asymptomatic, but their body composition, cellular, and humoral factors differ from healthy individuals. In this article, it has been discussed that after treatment of thyroid diseases, only in few conditions the status of thyroid returns to the healthy situation after discontinuation of therapy and majority of thyroid illnesses are managed as “controlled”, meaning that patients become asymptomatic. However, their thyroid structure, function, and biochemical factors fundamentally change. Therefore, patients may need additional permanent treatment to attain euthyroidism and especial follow-up for recurrence of the disease. For example, for Graves’ hyperthyroidism, all three forms of therapeutic approaches fail to re-establish continuous normal thyroid function in all patients. Long-term anti-thyroid drug therapy appears to cause an increase in the number of patients with Graves’ disease to attain a cure without further treatment.


QJM ◽  
2014 ◽  
Vol 108 (5) ◽  
pp. 379-385 ◽  
Author(s):  
Y. R. Yan ◽  
Y. Liu ◽  
H. Huang ◽  
Q. G. Lv ◽  
X. L. Gao ◽  
...  

2000 ◽  
pp. 189-196 ◽  
Author(s):  
F Delange ◽  
A Van Onderbergen ◽  
W Shabana ◽  
E Vandemeulebroucke ◽  
F Vertongen ◽  
...  

OBJECTIVE: Belgium is one of the Western European countries in which no program of iodine-deficiency correction using iodized salt has been implemented, in spite of well-documented mild iodine deficiency. In 1995, the median urinary iodine concentration was 55 microg/l (normal: 100-200) and the prevalence of goiter was 11% (normal: below 5%) in representative samples of schoolchildren aged 6-12 years. Based on these results, the authors of the present study and others had emphasized to health professionals and to the public the necessity for iodine supplementation. The objective of this study was to evaluate as to whether these efforts had resulted in an improvement in the status of iodine nutrition. DESIGN: We performed a national survey of the status of iodine nutrition in Belgium based on the determination of thyroid volume, obtained by ultrasonography, and urinary iodine concentrations in schoolchildren. METHODS: A mobile van equipped with an ultrasound instrument, a computer and a deep-freeze visited 23 schools selected from across the country. The sample included 2855 schoolchildren (1365 boys and 1490 girls) aged 6-12 years. RESULTS: The results show a homogeneous situation in the whole country, with a median urinary iodine concentration of 80 microg/l and a goiter prevalence of 5.7%. Urinary iodine slightly decreases with age in girls and reaches a critical value of 59 microg/l at the age of 12 years, together with a goiter prevalence of 18.4%. CONCLUSION: Iodine nutrition has improved slightly in Belgium but mild iodine deficiency continues, with public-health consequences. The improvement indicates silent iodine prophylaxis, as no official salt-iodization measures have been taken. Silent iodine prophylaxis only partly corrects iodine deficiency in Western Europe. Active measures, including the implementation of a program of salt iodization, are urgently required.


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