1949 TEMPORAL GENE EXPRESSION PROFILING OF PROTEINS INVOLVED IN CA 2+ -SENSITIZATION FOLLOWING PARTIAL BLADDER OUTLET OBSTRUCTION: MECHANISM FOR UPREGULATION OF RHOA AND ROKβ GENE EXPRESSION

2011 ◽  
Vol 185 (4S) ◽  
Author(s):  
Ettickan Boopathi ◽  
Stephen Zderic ◽  
Alan Wein ◽  
Samuel Chacko
Keyword(s):  
Gene Expression ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Bladder Outlet Obstruction ◽  
Outlet Obstruction ◽  
Temporal Gene Expression ◽  
Partial Bladder Outlet Obstruction

Temporal gene expression profiling of maslinic acid-treated Raji cells

2021 ◽  
Author(s):  
Wai Meng Lau ◽  
Menaga Subramaniam ◽  
Hoe Han Goh ◽  
Yang Mooi Lim
Keyword(s):  
Gene Expression ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Raji Cells ◽  
Maslinic Acid ◽  
Temporal Gene Expression ◽  
Key Pathways

An hourly progression of gene expression profiling in maslinic acid treated Raji cells, which reported activation of several key pathways.

Spatial and temporal gene expression profiling of the contused rat spinal cord

2004 ◽  
Vol 189 (2) ◽  
pp. 204-221 ◽  
Author(s):  
J AIMONE ◽  
J LEASURE ◽  
V PERREAU ◽  
M THALLMAIR ◽  
THECHRISTOPHERREEVEPARALYSISFOUNDA
Keyword(s):  
Gene Expression ◽  
Spinal Cord ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Rat Spinal Cord ◽  
Temporal Gene Expression

scholarly journals Hepatic Temporal Gene Expression Profiling in Helicobacter hepaticus-Infected A/JCr Mice

2004 ◽  
Vol 32 (6) ◽  
pp. 678-693 ◽  
Author(s):  
Samuel R. Boutin ◽  
Arlin B. Rogers ◽  
Zeli Shen ◽  
Rebecca C. Fry ◽  
Jennifer A. Love ◽  
...  
Keyword(s):  
Gene Expression ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Helicobacter Hepaticus ◽  
Temporal Gene Expression

5-Hydroxytryptamine-induced bladder hyperactivity via the 5-HT2A receptor in partial bladder outlet obstruction in rats

2013 ◽  
Vol 304 (7) ◽  
pp. F1020-F1027 ◽  
Author(s):  
Takumi Sakai ◽  
Ken-ichi Kasahara ◽  
Ken-ichi Tomita ◽  
Ichiro Ikegaki ◽  
Hiroshi Kuriyama
Keyword(s):  
Gene Expression ◽  
Bladder Outlet Obstruction ◽  
Smooth Muscles ◽  
Outlet Obstruction ◽  
Pcr Analysis ◽  
Receptor Subtypes ◽  
Rt Pcr ◽  
Contractile Responses ◽  
Partial Bladder Outlet Obstruction ◽  
Rat Bladder

We investigated the effects of partial bladder outlet obstruction (BOO) on the function and gene expression of 5-hydroxytryptamine (5-HT) receptor subtypes in rat bladder. Isometric contractions of the isolated bladders from sham-operated control and BOO rats were examined. The contractile responses to 5-HT were significantly increased in BOO rat bladder strips, while the responses to KCl, carbachol, or phenylephrine were not different from the control. The 5-HT-induced hypercontraction in BOO rat bladder strips was inhibited by ketanserin, a 5-HT2A receptor antagonist. The contractile responses to 5-HT in bladder strips were not affected by urothelium removal from the intact bladder. The gene expression of 5-HT receptor subtypes in the bladders was analyzed by RT-PCR. The mRNA expression of the 5-HT2A, 5-HT2B, 5-HT2C, 5-HT4, and 5-HT7 receptors was detected in both the control and BOO rat bladders. Quantitative RT-PCR analysis showed there was a significant increase of 5-HT2A receptor mRNA in the BOO rat bladder compared with the control bladder. On the other hand, the gene expression of the 5-HT4 receptor was not changed in the BOO rat bladder. These results suggest that the increased contractile responses to 5-HT in BOO rat bladder may be partly caused by 5-HT2A receptor upregulation in the detrusor smooth muscles.

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