scholarly journals 3:36 PM Abstract No. 203 Safety and efficacy of percutaneous computed tomography–guided transplant pancreas biopsy

2020 ◽  
Vol 31 (3) ◽  
pp. S93
Author(s):  
P. Self ◽  
D. Zarama ◽  
P. Shrestha ◽  
J. Golzarian ◽  
M. Rosenberg
Keyword(s):  
Computed Tomography ◽  
Safety And Efficacy ◽  
Pancreas Biopsy

scholarly journals Laparoscopic splenectomy and porto-azygos disconnection: clinical research in the treatment of portal hypertension

Open Medicine ◽  
2015 ◽  
Vol 10 (1) ◽  
Author(s):  
Wang Fengyong ◽  
Sun Yuanshui ◽  
Wu Yuewu ◽  
Zhan Weihua ◽  
Shi Jianfeng ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Laparoscopic Splenectomy ◽  
Operation Time ◽  
Spleen Volume ◽  
Spiral Computed ◽  
Curative Effect ◽  
Intraoperative Bleeding ◽  
Safety And Efficacy ◽  
Open Abdominal Surgery

Abstract To investigate the safety and efficacy of laparoscopic splenectomy and portaazygous devascularization, we studied laparoscopic splenectomy and porto-azygos devascularization patients within the peri-operative period. Clinical data and curative effect are detailed alongside statistical analysis. The laparoscopic splenectomy and porto-azygos devascularization operation time was 2.56 + 0.62 hours. The intraoperative bleeding and anal exhaust time was 149.5 + 32.7ml 3.47 + 1.32 days, and the hospitalization time was 5.05 + 1.22 days. When the spleen volume was greater than or equal to 1.5 liters, the rate of open abdominal surgery increased significantly. After 1, 2, 3, and 4 years of follow-up, cumulative recurrence bleeding rates were 0, 5.20%, 9.98%, and 15.83%, respectively. Laparoscopic splenectomy and pericardial devascularization is safe, effective, and feasible, and it can be confirmed by enhanced spiral computed tomography (CT). Whether spleen volume greater than 1.5L is suited to laparoscopic surgery requires further research.

Feasibility, Safety, and Efficacy of Flow-Diverting Stent-Assisted Microsphere Embolization of Fusiform and Sidewall Aneurysms

Neurosurgery ◽  
2015 ◽  
Vol 77 (1) ◽  
pp. 126-136 ◽  
Author(s):  
Andrea Nonn ◽  
Stefanie Kirschner ◽  
Giovanna Figueiredo ◽  
Martin Kramer ◽  
Omid Nikoubashman ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Protection System ◽  
Micro Computed Tomography ◽  
Beam Hardening ◽  
Safety And Efficacy ◽  
Aneurysm Occlusion ◽  
Flow Diverting Stent ◽  
Microsphere Embolization

Abstract BACKGROUND: Treatment of wide-necked internal carotid artery aneurysms is frequently associated with incomplete occlusion and high recurrence rates. Furthermore, platinum coils cause strong beam-hardening artifacts, hampering subsequent image analyses. OBJECTIVE: To assess the feasibility, safety, and efficacy of flow-diverting, stent-assisted microsphere embolization of fusiform and sidewall aneurysms in vitro and in vivo. METHODS: Using a recirculating pulsatile in vitro flow model, 5 different aneurysm geometries (inner/outer curve, narrow/wide neck, and fusiform) were treated (each n = 1) by flow-diverting stent (FDS) implantation and subsequent embolization through a jailed microcatheter using calibrated microspheres (500–900 μm) larger than the pores of the FDS mesh. Treatment effects were analyzed angiographically and by micro computed tomography. The fluid of the in vitro model was filtered to ensure that no microspheres evaded the aneurysm. The experiment was repeated once in vivo. RESULTS: In vitro, all 5 aneurysms were safely and completely occluded by FDS-assisted microsphere embolization. Virtually complete aneurysm occlusion was confirmed by angiography and micro computed tomography. No microspheres escaped into the circulation. The experiment was successfully repeated in 1 pig with a sidewall aneurysm generated by vessel occlusion. An embolic protection system placed distally of the FDS in vitro and in vivo (each n = 1) contained no microspheres after the embolization. Thus, no microspheres were lost in the circulation, and the use of an embolic protection system seems feasible to provide additional safety. CONCLUSION: FDS-assisted microsphere embolization of fusiform and sidewall aneurysms is feasible and yields virtually complete aneurysm occlusion while avoiding coil-associated beam-hardening artifacts.

scholarly journals Safety and efficacy of normobaric oxygenation on rescuing acute intracerebral hemorrhage-mediated brain damage—a protocol of randomized controlled trial

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Zhiying Chen ◽  
Jiayue Ding ◽  
Xiaoqin Wu ◽  
Bing Bao ◽  
Xianming Cao ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Intracerebral Hemorrhage ◽  
Brain Damage ◽  
Controlled Trial ◽  
Low Flow ◽  
Control Group ◽  
Oxygen Control ◽  
Safety And Efficacy ◽  
High Flow Oxygen ◽  
Secondary Endpoints

Abstract Background All of the existing medication and surgical therapies currently cannot completely inhibit intracerebral hemorrhage (ICH)-mediated brain damage, resulting in disability in different degrees in the involved patients. Normobaric oxygenation (NBO) was reported attenuating ischemic brain injury. Herein, we aimed to explore the safety and efficacy of NBO on rescuing the damaged brain tissues secondary to acute ICH, especially those in the perihematoma area being threatened by ischemia and hypoxia. Methods A total of 150 patients confirmed as acute spontaneous ICH by computed tomography (CT) within 6 h after symptoms onset, will enroll in this study after signing the informed consent, and enter into the NBO group or control group randomly according to a random number. In the NBO group, patients will inhale high-flow oxygen (8 L/min, 1 h each time for 6 cycles daily) and intake low-flow oxygen (2 L/min) in intermittent periods by mask for a total of 7 days. While in the control group, patients will breathe in only low-flow oxygen (2 L/min) by mask for 7 consecutive days. Computed tomography and perfusion (CT/CTP) will be used to evaluate cerebral perfusion status and brain edema. CT and CTP maps in the two groups at baseline and day 7 and 14 after NBO or low-flow oxygen control will be compared. The primary endpoint is mRS at both Day14 post-ICH and the end of the 3rd month follow-up. The secondary endpoints include NIHSS and plasma biomarkers at baseline and Day-1, 7, and 14 after treatment, as well as the NIHSS at the end of the 3rd month post-ICH and the incidence of bleeding recurrence and the mortalities within 3 months post-ICH. Discussion This study will provide preliminary clinical evidence about the safety and efficacy of NBO on correcting acute ICH and explore some mechanisms accordingly, to offer reference for larger clinical trials in the future. Trial registration ClinicalTrials.gov NCT04144868. Retrospectively registered on October 29, 2019.

scholarly journals Ultrasonography versus computed tomography for initial investigation of suspected nephrolithiasis

CJEM ◽  
2016 ◽  
Vol 18 (4) ◽  
pp. 315-318 ◽  
Author(s):  
Katie Lin ◽  
Shawn Dowling
Keyword(s):  
Computed Tomography ◽  
Clinical Question ◽  
First Line ◽  
Safety And Efficacy ◽  
Initial Investigation ◽  
Line Imaging

Clinical questionIs ultrasonography a safe and practical alternative to computed tomography for the initial investigation of suspected nephrolithiasis?Article chosenSmith-Bindman R, Aubin C, Bailitz J, et al. Ultrasonography versus computed tomography for suspected nephrolithiasis. N Engl J Med 2014;371(12):1100-10.ObjectiveTo assess the safety and efficacy of ultrasonography as a first-line imaging investigation for patients with suspected nephrolithiasis.

Safety and efficacy of patient preparation with intravenous esmolol before 64-slice computed tomography coronary angiography

2008 ◽  
Vol 19 (1) ◽  
pp. 33-36 ◽  
Author(s):  
Muzaffer Degertekin ◽  
Gökmen Gemici ◽  
Zafer Kaya ◽  
Fatih Bayrak ◽  
Tahsin Guneysu ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Coronary Angiography ◽  
Computed Tomography Coronary Angiography ◽  
Safety And Efficacy ◽  
Patient Preparation
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